Hypovolemia in Syncope and Orthostatic Intolerance Role of the Renin-Angiotensin System

• Published in: The American journal of medicine Vol. 103; no. 2; pp. 128 - 133
• Main Authors: Jacob, Giris, Robertson, David, Mosqueda-Garcia, Rogelio, Ertl, Andrew C., Robertson, Rose Marie, Biaggioni, Italo
• Format: Journal Article
• Language: English
• Published: Legacy CDMS Elsevier Inc 01.08.1997; Elsevier; Elsevier Sequoia S.A
• Subjects: Adolescent; Adult; Aerospace Medicine; Antihypertensive agents; Biological and medical sciences; Blood Pressure; Blood Volume; Cardiovascular system; Catecholamines - blood; Female; Heart Rate; Humans; Hypotension, Orthostatic - blood; Hypotension, Orthostatic - complications; Hypotension, Orthostatic - etiology; Hypotension, Orthostatic - physiopathology; Kidneys; Male; Medical disorders; Medical research; Medical sciences; Pharmacology. Drug treatments; Renin-Angiotensin System; Syncope - blood; Syncope - etiology; Syncope - physiopathology; Blood Pressure; Human; Support, U.s. Gov't, Non-P.h.s; Heart Rate; Support, Non-U.s. Gov't; Support, U.s. Gov't, P.h.s; Non-Nasa Center; Male; Renin-Angiotensin System; Nasa Discipline Regulatory Physiology; Hypotension, Orthostatic/blood/complications/etiology/physiopathology; Adolescent; Catecholamines/blood; Blood Volume; Adult; Female; Syncope/blood/etiology/physiopathology; Kidney disease; Evaluation; Nervous system diseases; Urinary system disease; Pathophysiology; Hypovolemia; Consciousness impairment; Cardiovascular disease; Vascular disease; Renin angiotensin system; Syncope; Neurological disorder; Therapeutic protocol; Orthostatic tolerance; NASA Discipline Regulatory Physiology; Non-NASA Center

PURPOSE: Orthostatic intolerance is the cause of significant disability in otherwise normal patients. Orthostatic tachycardia is usually the dominant hemodynamic abnormality, but symptoms may include dizziness, visual changes, discomfort in the head or neck, poor concentration, fatigue, palpitations...