Associations of T helper 1, 2, 17 and regulatory T lymphocytes with mortality in severe sepsis

• Published in: Inflammation research Vol. 62; no. 8; pp. 751 - 763
• Main Authors: Wu, Huang-Pin, Chung, Kong, Lin, Chun-Yao, Jiang, Bor-Yiing, Chuang, Duen-Yau, Liu, Yu-Chih
• Format: Journal Article
• Language: English
• Published: Basel Springer Basel 01.08.2013; Springer Nature B.V
• Subjects: Aged; Allergology; Biomedical and Life Sciences; Biomedicine; Dermatology; Female; Humans; Immunology; Lymphocyte Count; Male; Middle Aged; Neurology; Original Research Paper; Pharmacology/Toxicology; Rheumatology; Sepsis - immunology; Sepsis - mortality; T-Lymphocyte Subsets - immunology; T-Lymphocytes, Helper-Inducer - immunology; T-Lymphocytes, Regulatory - immunology; Regulatory T lymphocytes; T helper 17 lymphocytes; Severe sepsis; Mortality; T helper 1 lymphocytes

Objective and design T helper 17 (Th17) and regulatory T (T reg ) lymphocytes might play important roles in patients with severe sepsis. The association of Th17 or T reg lymphocytes with survival is also unclear. Methods Eighty-seven patients with severe sepsis were enrolled from our intensive care...