Mechanism of TH2/TH17-predominant and neutrophilic TH2/TH17-low subtypes of asthma - Liu, Weimin; Liu, Sucai; Verma, Mukesh; Zafar, Iram; Good, James T.; Rollins, Donald; Groshong, Stephen; Gorska, Magdalena M.; Martin, Richard J.; Alam, Rafeul (Journal of allergy and clinical immunology, 2017)
Keywords: Allergy and Immunology; Alveoli; Asthma; Asthma endotype; Bronchus; C3a; Cell culture; Colonies; Colony-stimulating factor; Cytokines; Flow cytometry; Gene expression; Genotype & phenotype; Granulocyte colony-stimulating factor; Granulocyte-macrophage colony-stimulating factor; Growth factors; Helper cells; Human subjects; IL-1; infection; Inflammation; Interleukin 1; Interleukin 1 receptor antagonist; Interleukin 23; Interleukin 6; Interleukin 8; Kinases; Leukocytes (granulocytic); Leukocytes (neutrophilic); Lymphocytes; Lymphocytes T; MAP kinase; neutrophilic asthma; Peroxidase; Protein kinase; Smooth muscle; Subclinical infection; TH2/TH17-predominant asthma; Uric acid; β-Amyloid; C3a; infection; STAT; IL-1; TH2/TH17-predominant asthma; neutrophilic asthma; Asthma endotype; IL-1R; MAPK; BAL; G-CSF; DAMP; SAA; serum amyloid A; Th2/Th17-predominant asthma; IL1; danger-associated molecular pattern