Participation of hippocampal nicotinic receptors in acquisition, consolidation and retrieval of memory for one trial inhibitory avoidance in rats

• Published in: Neuroscience Vol. 126; no. 3; pp. 651 - 656
• Main Authors: Martí Barros, D., Ramirez, M.R., dos Reis, E.A., Izquierdo, I.
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 2004; Elsevier
• Subjects: Animals; Avoidance Learning - drug effects; Avoidance Learning - physiology; Biological and medical sciences; dihydro-beta-erythroidine; Fundamental and applied biological sciences. Psychology; hippocampus; Hippocampus - drug effects; Hippocampus - metabolism; Injections, Intraventricular; Male; Maze Learning - drug effects; Maze Learning - physiology; mecamylamine; memory; Memory - drug effects; Memory - physiology; nicotine; Nicotinic Agonists - administration & dosage; Nicotinic Antagonists - administration & dosage; Rats; Rats, Wistar; Receptors, Nicotinic - drug effects; Receptors, Nicotinic - metabolism; Vertebrates: nervous system and sense organs; mecamylamine; nicotine; memory; hippocampus; LTM; nAChR; DHβE; STM; dihydro-beta-erythroidine; Memory retrieval; Rat; Memory; Rodentia; Central nervous system; Encephalon; Cholinergic receptor; Vertebrata; Mammalia; Animal; Nicotinic receptor; Avoidance; Hippocampus

One-trial step-down inhibitory avoidance in rats involves the activation of two separate memory types, a short-term system (STM) that lasts 3–6 h, and a long-term system (LTM) that takes 3–6 h to be formed and lasts for many days or even months. Here we investigate the effect of nicotinic receptor (...