Natural SARS-CoV-2 Infection Affects Neutralizing Activity in Saliva of Vaccinees

• Published in: Frontiers in immunology Vol. 13; p. 820250
• Main Authors: Garziano, Micaela, Utyro, Olga, Poliseno, Mariacristina, Santantonio, Teresa Antonia, Saulle, Irma, Strizzi, Sergio, Lo Caputo, Sergio, Clerici, Mario, Introini, Andrea, Biasin, Mara
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 11.03.2022
• Subjects: antibodies; Antibodies, Neutralizing; COVID-19; COVID-19 Vaccines; Humans; Immunology; neutralizing activity; Saliva; SARS-CoV-2; Spike Glycoprotein, Coronavirus; variants; saliva; SARS-CoV-2; neutralizing activity; antibodies; variants

SARS-CoV-2 transmission mainly occurs through exposure of the upper airway mucosa to infected secretions such as saliva, which are excreted by an infected person. Thus, oral mucosal immunity plays a central role in the prevention of and early defense against SARS-CoV-2 infection. Although virus-spec...