Effect of isobutyl methacrylate and methacrylic acid eluted from chairside denture hard reliners on enzymatic cellular antioxidants: An in vitro study in human primary buccal mucosal fibroblasts

• Published in: The journal of Indian Prosthodontic Society Vol. 17; no. 2; pp. 189 - 195
• Main Authors: Jagdish, Sivanesan Karthikeyan, Ganeshkumar, Anbazhagan, Shakila, Rajaraman, Singh, Shyam, Jesudas, Balasubramanian, Karthikeyan, Sivanesan
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.04.2017; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd; Wolters Kluwer Medknow Publications
• Subjects: Antioxidants; Antioxidants (Nutrients); Apoptosis; Buccal mucosa; Catalase; Cell culture; Cell viability; Chairside reliners; College campuses; Cytotoxicity; Dentures; Enzymatic activity; enzymatic antioxidants; Enzymes; Fibroblasts; free radical; Free radicals; Glutathione peroxidase; Leaching; Methacrylic acid; Monomers; Original; Oxidative stress; Pharmacology; Reactive oxygen species; Resins; Statistical analysis; Studies; Superoxide dismutase; Tissue culture; Toxicity; Toxicology; United States > US; Chairside reliners; enzymatic antioxidants; free radical; cytotoxicity; oxidative stress

This study was conducted with the objective to evaluate the cytotoxicity of monomers isobutyl methacrylate (IBMA) and methacrylic acid (MA) in human buccal mucosal fibroblast primary cell culture and to study their effect on cellular enzymatic antioxidants-glutathione peroxidase (GPx), superoxide di...