Thalidomide embryopathy: Follow-up of cases born between 1959 and 2010

• Published in: Birth defects research. A Clinical and molecular teratology Vol. 103; no. 9; p. 794
• Main Authors: Kowalski, Thayne Woycinck, Sanseverino, Maria Teresa Vieira, Schuler-Faccini, Lavinia, Vianna, Fernanda Sales Luiz
• Format: Journal Article
• Language: English
• Published: United States 01.09.2015
• Subjects: Abnormalities, Drug-Induced - physiopathology; Abnormalities, Multiple - chemically induced; Abnormalities, Multiple - physiopathology; Adolescent; Adult; Brazil; Child, Preschool; Female; Fetal Diseases - chemically induced; Fetal Diseases - physiopathology; Follow-Up Studies; Health Status; Humans; Limb Deformities, Congenital - chemically induced; Limb Deformities, Congenital - physiopathology; Male; Middle Aged; Phenotype; Thalidomide - adverse effects; Young Adult; Brazil; embryopathy; teratogenesis; thalidomide; limb reduction defects; late effects

Thalidomide is a known teratogen and it is estimated that more than ten thousand babies were affected by thalidomide embryopathy (TE), which is characterized mainly by limb defects, but can involve many organs and systems. Most people with TE were only evaluated at birth and it is not well establish...