Thiol-Ene Click Chemistry

• Published in: Angewandte Chemie International Edition Vol. 49; no. 9; pp. 1540 - 1573
• Main Authors: Hoyle, Charles E, Bowman, Christopher N
• Format: Journal Article
• Language: English
• Published: Weinheim Wiley-VCH Verlag 22.02.2010; WILEY-VCH Verlag; WILEY‐VCH Verlag
• Subjects: Acrylates - chemistry; Biocompatible Materials - chemistry; click chemistry; Dendrimers - chemical synthesis; Dendrimers - chemistry; Free Radicals - chemistry; Michael additions; Nanostructures - chemistry; Photochemical Processes; polymerization; Polymers - chemistry; Sulfhydryl Compounds - chemistry; Sulfhydryl Compounds - toxicity; Surface Properties; synthesis design; thiol-ene reaction

Following Sharpless′ visionary characterization of several idealized reactions as click reactions, the materials science and synthetic chemistry communities have pursued numerous routes toward the identification and implementation of these click reactions. Herein, we review the radical-mediated thio...