Association of Diurnal Patterns in Salivary Cortisol With Type 2 Diabetes in the Whitehall II Study

• Published in: The journal of clinical endocrinology and metabolism Vol. 99; no. 12; pp. 4625 - 4631
• Main Authors: Hackett, Ruth A, Steptoe, Andrew, Kumari, Meena
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Endocrine Society 01.12.2014; Copyright by The Endocrine Society
• Subjects: Aged; Arousal; Biological and medical sciences; Circadian Rhythm; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2 - metabolism; Diabetes. Impaired glucose tolerance; Endocrine pancreas. Apud cells (diseases); Endocrine Research; Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Feeding. Feeding behavior; Female; Fundamental and applied biological sciences. Psychology; Humans; Hydrocortisone - metabolism; Male; Medical sciences; Middle Aged; Saliva - metabolism; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Vertebrates: endocrinology; Endocrinopathy; Type 2 diabetes; Corticosteroid; Obesity; Nutrition; Steroid hormone; Nutrition disorder; Antiinflammatory agent; Metabolic diseases; Cortisol; Hydrocortisone; Glucocorticoid; Epidemiology; Prospective; Association; Cohort study; Adrenal hormone; Saliva; Endocrinology; Nutritional status; Public health

Context: The hypothalamic pituitary-adrenal axis is thought to play a role in Type 2 Diabetes (T2D). However, the evidence for an association between diurnal cortisol patterns and T2D is equivocal. Objective: The aim was to examine the association of cortisol patterns throughout the day with T2D sta...