All‐cause mortality of elderly Australian veterans using COX‐2 selective or non‐selective NSAIDs: a longitudinal study

• Published in: British journal of clinical pharmacology Vol. 71; no. 6; pp. 936 - 942
• Main Authors: Kerr, Stephen J., Rowett, Debra S., Sayer, Geoffrey P., Whicker, Susan D., Saltman, Deborah C., Mant, Andrea
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.06.2011; Blackwell; Blackwell Science Inc
• Subjects: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal - adverse effects; Australia; Biological and medical sciences; Cohort Studies; COX‐2 selective NSAIDs; Cyclooxygenase 2 Inhibitors - adverse effects; Female; Humans; Longitudinal Studies; longitudinal study; Male; Medical sciences; Mortality; NSAIDs; Pharmacoepidemiology; Pharmacology. Drug treatments; Proportional Hazards Models; Risk Factors; Veterans; Australia; Oceania; Human; veterans; Enzyme; Cyclooxygenase 2; Mortality; longitudinal study; COX-2 selective NSAIDs; Non steroidal antiinflammatory agent; Follow up study; NSAIDs; Oxidoreductases; Veteran; Elderly

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Previous studies have found varying impact of exposure to COX‐2 selective and non‐selective NSAIDs. WHAT THIS STUDY ADDS • Individuals receiving a COX‐2 selective NSAID had an increased risk of all‐cause mortality after correction for age, sex and cardiovas...