Degarelix, a novel GnRH antagonist, causes minimal histamine release compared with cetrorelix, abarelix and ganirelix in an ex vivo model of human skin samples - Koechling, Wolfgang; Hjortkjaer, Rolf; Tankó, László B. (British journal of clinical pharmacology, 2010)
Keywords: abarelix; Biological and medical sciences; cetrorelix; degarelix; Drug Safety; ganirelix; Gonadotropin-Releasing Hormone - analogs & derivatives; Gonadotropin-Releasing Hormone - antagonists & inhibitors; Gonadotropin-Releasing Hormone - pharmacology; histamine; Histamine - analysis; Histamine Release - drug effects; human skin; Humans; Medical sciences; Oligopeptides - pharmacology; Pharmacology. Drug treatments; Skin - drug effects; Human; Abarelix; Decapeptide; Peptides; Gonadotropin RH; Assisted procreation; Antihormone; Ganirelix; Degarelix; Hypothalamic hormone; Histamine; In vivo; Ex vivo; human skin; Models; Skin; Antagonist; Hormone releasing factor; Cetrorelix; Comparative study; Release