Therapeutic Versatility of Resveratrol Derivatives

Resveratrol, a natural phytoalexin, exhibits a remarkable range of biological activities, such as anticancer, cardioprotective, neuroprotective and antioxidant properties. However, the therapeutic application of resveratrol was encumbered for its low bioavailability. Therefore, many researchers focu...

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Published inNutrients Vol. 9; no. 11; p. 1188
Main Authors Nawaz, Waqas, Zhou, Zhongqin, Deng, Sa, Ma, Xiaodong, Ma, Xiaochi, Li, Chuangang, Shu, Xiaohong
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 29.10.2017
MDPI
Subjects
Antineoplastic Agents - chemistry
Antineoplastic Agents - pharmacology
antioxidant activity
Antioxidants - chemistry
Antioxidants - pharmacology
Bioavailability
Cardiovascular Agents - chemistry
Cardiovascular Agents - pharmacology
Humans
hydroxylation
medicinal properties
Molecular Structure
Neuroprotective Agents - chemistry
Neuroprotective Agents - pharmacology
phytoalexins
resveratrol
Review
Stilbenes - chemistry
Stilbenes - pharmacology
structure-activity relationships
therapeutics
resveratrol derivatives
pharmacological activity
resveratrol
structure-activity relationship
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Abstract Resveratrol, a natural phytoalexin, exhibits a remarkable range of biological activities, such as anticancer, cardioprotective, neuroprotective and antioxidant properties. However, the therapeutic application of resveratrol was encumbered for its low bioavailability. Therefore, many researchers focused on designing and synthesizing the derivatives of resveratrol to enhance the bioavailability and the pharmacological activity of resveratrol. During the past decades, a large number of natural and synthetic resveratrol derivatives were extensively studied, and the methoxylated, hydroxylated and halogenated derivatives of resveratrol received particular more attention for their beneficial bioactivity. So, in this review, we will summarize the chemical structure and the therapeutic versatility of resveratrol derivatives, and thus provide the related structure activity relationship reference for their practical applications.
AbstractList Resveratrol, a natural phytoalexin, exhibits a remarkable range of biological activities, such as anticancer, cardioprotective, neuroprotective and antioxidant properties. However, the therapeutic application of resveratrol was encumbered for its low bioavailability. Therefore, many researchers focused on designing and synthesizing the derivatives of resveratrol to enhance the bioavailability and the pharmacological activity of resveratrol. During the past decades, a large number of natural and synthetic resveratrol derivatives were extensively studied, and the methoxylated, hydroxylated and halogenated derivatives of resveratrol received particular more attention for their beneficial bioactivity. So, in this review, we will summarize the chemical structure and the therapeutic versatility of resveratrol derivatives, and thus provide the related structure activity relationship reference for their practical applications.
Resveratrol, a natural phytoalexin, exhibits a remarkable range of biological activities, such as anticancer, cardioprotective, neuroprotective and antioxidant properties. However, the therapeutic application of resveratrol was encumbered for its low bioavailability. Therefore, many researchers focused on designing and synthesizing the derivatives of resveratrol to enhance the bioavailability and the pharmacological activity of resveratrol. During the past decades, a large number of natural and synthetic resveratrol derivatives were extensively studied, and the methoxylated, hydroxylated and halogenated derivatives of resveratrol received particular more attention for their beneficial bioactivity. So, in this review, we will summarize the chemical structure and the therapeutic versatility of resveratrol derivatives, and thus provide the related structure activity relationship reference for their practical applications.Resveratrol, a natural phytoalexin, exhibits a remarkable range of biological activities, such as anticancer, cardioprotective, neuroprotective and antioxidant properties. However, the therapeutic application of resveratrol was encumbered for its low bioavailability. Therefore, many researchers focused on designing and synthesizing the derivatives of resveratrol to enhance the bioavailability and the pharmacological activity of resveratrol. During the past decades, a large number of natural and synthetic resveratrol derivatives were extensively studied, and the methoxylated, hydroxylated and halogenated derivatives of resveratrol received particular more attention for their beneficial bioactivity. So, in this review, we will summarize the chemical structure and the therapeutic versatility of resveratrol derivatives, and thus provide the related structure activity relationship reference for their practical applications.
Author Ma, Xiaodong
Shu, Xiaohong
Zhou, Zhongqin
Nawaz, Waqas
Deng, Sa
Ma, Xiaochi
Li, Chuangang
AuthorAffiliation 1 College of Pharmacy, Dalian Medical University, Dalian 116044, China; imwaqasnawaz@yahoo.com (W.N.); dengsa31@163.com (S.D.); xiaodong.ma@139.com (X.M.); maxc1978@163.com (X.M.)
2 Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China; zzq0060@hotmail.com
3 The Second Affiliated Hospital, Dalian Medical University, Dalian 116023, China
AuthorAffiliation_xml – name: 3 The Second Affiliated Hospital, Dalian Medical University, Dalian 116023, China
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Cites_doi 10.1021/jf1043019
10.1196/annals.1397.051
10.1007/s00280-008-0704-z
10.1002/ptr.5185
10.1016/j.foodchem.2012.05.043
10.1159/000325216
10.1016/j.neurobiolaging.2011.08.015
10.3892/ijo.2016.3635
10.1007/s00394-004-0471-5
10.1021/jf071520h
10.1007/s00436-007-0729-y
10.1158/1535-7163.11.3.1
10.1002/acn3.282
10.1021/jf900531m
10.1002/jcb.22405
10.1016/j.prostaglandins.2011.12.003
10.1155/2013/575482
10.4062/biomolther.2014.112
10.1002/jmv.24271
10.1021/acs.jafc.5b00002
10.1161/01.HYP.1.1.31
10.1016/j.jpba.2010.03.028
10.1016/j.bbrc.2011.04.133
10.1016/j.numecd.2013.01.002
10.1211/jpp.58.11.0004
10.1016/j.bbadis.2015.01.014
10.1007/s12013-012-9377-7
10.1016/j.toxlet.2009.05.005
10.1248/bpb.18.401
10.1016/j.fct.2013.03.038
10.1155/2012/603678
10.1093/cvr/cvp359
10.1007/s11095-010-0090-1
10.1016/j.ejphar.2016.02.052
10.1089/jmf.2010.0272
10.1007/s00018-014-1808-8
10.1007/s11010-014-1983-9
10.1124/dmd.106.013664
10.1111/j.1755-5949.2008.00074.x
10.3945/an.115.011627
10.1007/s10495-011-0653-6
10.1021/jf404694y
10.1016/j.biopha.2014.02.001
10.1002/mnfr.200700252
10.1016/j.biocel.2010.05.007
10.1016/j.tiv.2008.03.002
10.1080/15287390490514642
10.1042/BJ20050094
10.1111/j.1749-6632.2010.05853.x
10.1016/j.jconrel.2014.09.002
10.1124/mol.110.064535
10.1021/jf030073c
10.1211/jpp.58.11.0009
10.1194/jlr.M800112-JLR200
10.1111/j.1749-6632.2010.05842.x
10.1021/jf903067g
10.1002/ptr.2334
10.1177/0960327110368739
10.1093/carcin/bgp121
10.1111/nyas.13401
10.1021/jf0580364
10.1016/j.exphem.2006.05.018
10.1158/0008-5472.CAN-15-2722
10.1111/j.1749-6632.2010.05871.x
10.1093/jac/dkm099
10.1016/j.chembiol.2013.09.019
10.1038/jid.2009.376
10.1016/j.bmc.2004.08.008
10.18632/oncotarget.15041
10.1016/j.pharmthera.2017.03.007
10.1038/sj.bjc.6601568
10.1016/j.bcp.2004.12.001
10.1016/j.bmc.2009.02.014
10.1016/j.jnutbio.2007.06.001
10.3390/ijms141122483
10.1038/aps.2013.60
10.1016/j.jss.2011.09.054
10.1016/j.bmc.2015.08.031
10.1016/j.ejphar.2016.07.046
10.1186/1472-6882-13-238
10.1002/mnfr.201100143
10.1111/j.1476-5381.2010.00785.x
10.1016/j.ejphar.2008.03.027
10.1016/j.bmcl.2012.08.108
10.1002/ptr.2277
10.1016/j.fct.2014.07.038
10.18632/oncotarget.17879
10.1124/mol.104.009043
10.3109/10408363.2013.805182
10.1016/j.taap.2013.07.019
10.1002/mnfr.200800123
10.1111/exd.12721
10.1002/bmc.1254
10.1016/j.jpba.2011.08.020
10.1016/j.cbi.2013.12.009
10.1021/jf4004175
10.1016/j.bmc.2011.08.008
10.1016/j.jpba.2008.10.042
10.1016/j.bmcl.2011.12.095
10.1111/nyas.13372
10.2174/15734064113096660053
10.1016/j.lfs.2004.07.002
10.1016/j.bioorg.2006.04.001
10.1016/j.biocel.2009.08.005
10.1186/1471-2407-5-97
10.1097/FJC.0000000000000082
10.1007/s00216-015-8762-7
10.1016/j.neuint.2015.07.017
10.3233/CH-2011-1424
10.1021/jf802279h
10.1016/j.bbrc.2012.12.017
10.1002/1521-3765(20020916)8:18<4191::AID-CHEM4191>3.0.CO;2-S
10.1161/CIRCULATIONAHA.105.535294
10.1021/jf0116855
10.1093/carcin/bgs244
10.1016/j.bmc.2009.05.007
10.1021/jf0112973
10.1016/j.bcp.2006.05.023
10.1593/neo.04337
10.1002/mnfr.200800331
10.1242/bio.20121875
10.1016/j.bcp.2009.06.109
10.1139/bcb-2014-0136
10.1016/j.medici.2016.03.003
10.1016/j.bbadis.2014.10.005
10.1016/j.canlet.2009.05.011
10.1111/j.1349-7006.2008.00948.x
10.1016/j.bbamcr.2014.10.030
10.1016/j.abb.2010.06.011
10.1093/jn/132.2.298
10.1002/mc.20352
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Issue 11
Keywords resveratrol derivatives
pharmacological activity
resveratrol
structure-activity relationship
Language English
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References Duarte (ref_121) 2008; 22
Burns (ref_3) 2002; 50
Pan (ref_18) 2008; 47
Larrosa (ref_111) 2003; 51
Rimando (ref_49) 2005; 53
Fan (ref_94) 2009; 17
Wolter (ref_115) 2002; 132
Poulose (ref_46) 2015; 89
Joseph (ref_47) 2008; 56
Li (ref_82) 2009; 78
Horvath (ref_136) 2006; 34
Guo (ref_41) 2016; 776
Roupe (ref_100) 2006; 58
Kim (ref_112) 2008; 49
Belleri (ref_60) 2005; 67
Khurana (ref_106) 2005; 112
McCormack (ref_30) 2013; 2013
Yang (ref_54) 2009; 53
Kursvietiene (ref_2) 2016; 52
Zhang (ref_40) 2012; 17
Pavanetto (ref_128) 2011; 27
Singh (ref_137) 2014; 194
Cheng (ref_97) 2006; 34
Kasiotis (ref_43) 2013; 61
Kosuru (ref_25) 2016; 789
Murias (ref_132) 2008; 22
Androutsopoulos (ref_66) 2015; 24
Nguyen (ref_61) 2016; 76
ref_120
Wang (ref_55) 2012; 22
Jennings (ref_79) 2012; 302
Savio (ref_23) 2009; 41
Chun (ref_73) 2009; 189
Zhang (ref_85) 2010; 78
Das (ref_20) 2011; 19
Ruotolo (ref_92) 2013; 23
Kuo (ref_116) 2008; 52
Kucinska (ref_134) 2014; 209
Nguyen (ref_142) 2013; 20
Jennings (ref_78) 2010; 299
Kinoshita (ref_104) 2013; 430
Liu (ref_56) 2014; 63
Zhang (ref_58) 2015; 1853
Bourgault (ref_143) 2011; 410
Weiskirchen (ref_4) 2016; 7
Sharma (ref_124) 1999; 36
Barton (ref_113) 2004; 3
Sale (ref_64) 2004; 90
Chen (ref_86) 2015; 407
Pan (ref_81) 2010; 58
Matsumura (ref_96) 1995; 18
Magyar (ref_42) 2012; 50
Kumar (ref_38) 2017; 1403
Remsberg (ref_26) 2008; 22
Alex (ref_59) 2010; 109
Chun (ref_72) 2001; 61
Nagaradja (ref_144) 2015; 23
Huang (ref_34) 2013; 61
Yang (ref_12) 2017; 8
Tsai (ref_52) 2013; 272
Yang (ref_14) 2015; 70
ref_88
Gosslau (ref_71) 2008; 587
Piotrowska (ref_68) 2014; 68
Cichocki (ref_70) 2014; 391
Saiko (ref_133) 2008; 19
Kim (ref_109) 2008; 19
Hasiah (ref_29) 2011; 30
Moran (ref_140) 2009; 17
Ma (ref_62) 2008; 63
Mishra (ref_123) 1999; 37
Patel (ref_10) 2011; 1215
Li (ref_83) 2010; 160
Lin (ref_80) 2012; 57
Balan (ref_93) 2006; 72
Kim (ref_127) 2007; 1095
Ferrer (ref_37) 2005; 7
Pan (ref_35) 2007; 55
Fang (ref_98) 2002; 8
Walle (ref_11) 2011; 1215
Chai (ref_107) 2012; 2012
Szekeres (ref_15) 2010; 27
Lin (ref_50) 2010; 53
Murias (ref_22) 2005; 69
Chen (ref_67) 2013; 34
Locatelli (ref_19) 2005; 389
Kulkarni (ref_6) 2015; 1852
Liu (ref_119) 2010; 42
Chang (ref_44) 2012; 33
Lin (ref_51) 2009; 49
Weng (ref_53) 2009; 57
Larrosa (ref_110) 2004; 43
Paulitschke (ref_135) 2010; 130
Park (ref_8) 2015; 1852
Docherty (ref_125) 2007; 59
Pan (ref_33) 2009; 30
Kedzierski (ref_122) 2007; 102
Murias (ref_131) 2004; 12
Smoliga (ref_7) 2011; 55
Bitterman (ref_13) 2015; 72
Rimando (ref_28) 2002; 50
Crofton (ref_76) 1979; 1
Lin (ref_27) 2009; 23
Saw (ref_45) 2014; 72
Lin (ref_63) 2011; 59
Sosinska (ref_130) 2013; 14
Malik (ref_77) 2012; 98
Estrela (ref_21) 2013; 50
Setoguchi (ref_99) 2014; 62
Tang (ref_101) 2014; 28
Lee (ref_141) 2004; 75
Wicklow (ref_9) 2015; 93
Delmas (ref_16) 2011; 1215
Wawszczyk (ref_32) 2014; 71
Lappano (ref_91) 2009; 53
Gao (ref_57) 2012; 64
Bastianetto (ref_129) 2009; 15
Li (ref_74) 2017; 178
Lee (ref_114) 2009; 285
Pari (ref_48) 2006; 58
Angeles (ref_126) 2016; 3
Coppa (ref_95) 2011; 14
Lancon (ref_117) 2007; 35
Li (ref_24) 2012; 135
ref_39
Hong (ref_69) 2014; 22
Chun (ref_75) 2003; 523–524
Lee (ref_84) 2004; 67
Han (ref_139) 2015; 87
Kimura (ref_87) 2016; 36
Kim (ref_118) 2008; 19
Kimura (ref_89) 2008; 99
Huang (ref_105) 2012; 1
Clouser (ref_138) 2012; 22
Lee (ref_108) 2010; 501
Yang (ref_102) 2011; 1
Francioso (ref_5) 2014; 10
Kuczmarska (ref_17) 2015; 61
McCormack (ref_31) 2012; 173
Wu (ref_36) 2015; 63
Maccario (ref_90) 2012; 33
Choi (ref_103) 2010; 85
Biasutto (ref_1) 2017; 1403
Androutsopoulos (ref_65) 2016; 49
27475678 - Eur J Pharmacol. 2016 Oct 15;789:229-243
18286288 - Cancer Chemother Pharmacol. 2008 Dec;63(1):27-35
17132206 - J Pharm Pharmacol. 2006 Nov;58(11):1443-50
15464834 - Life Sci. 2004 Oct 22;75(23):2829-39
18357382 - Oncol Rep. 2008 Apr;19(4):961-7
20852048 - Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1891-901
16822479 - Biochem Pharmacol. 2006 Aug 28;72(5):573-81
24625210 - J Agric Food Chem. 2014 Mar 26;62(12 ):2541-8
21880495 - Bioorg Med Chem. 2011 Sep 15;19(18):5321-33
26212523 - Neurochem Int. 2015 Oct;89:227-33
10641182 - Indian J Exp Biol. 1999 Apr;37(4):418-20
15513897 - J Toxicol Environ Health A. 2004 Dec;67(23-24):1987-2000
25217813 - J Control Release. 2014 Nov 28;194:178-88
19228181 - CNS Neurosci Ther. 2009 Winter;15(1):76-83
19679195 - Int J Biochem Cell Biol. 2009 Dec;41(12):2493-502
15736313 - Neoplasia. 2005 Jan;7(1):37-47
17726731 - Phytother Res. 2008 Feb;22(2):169-79
16172288 - Circulation. 2005 Sep 20;112(12):1813-24
24768110 - Biomed Pharmacother. 2014 May;68(4):397-400
28662290 - Ann N Y Acad Sci. 2017 Sep;1403(1):15-26
16712899 - Bioorg Chem. 2006 Jun;34(3):142-57
27287718 - Cancer Res. 2016 Aug 15;76(16):4887-96
20427141 - J Pharm Biomed Anal. 2010 Nov 2;53(3):693-7
27496184 - Medicina (Kaunas). 2016;52(3):148-55
21554123 - J Med Food. 2011 Oct;14 (10 ):1173-80
19441815 - J Agric Food Chem. 2009 Jun 24;57(12):5235-43
29088756 - Oncotarget. 2017 May 16;8(43):73905-73924
26305052 - Biochem Cell Biol. 2015 Oct;93(5):522-30
19447859 - Carcinogenesis. 2009 Jul;30(7):1234-42
25745778 - Acta Pol Pharm. 2014 Nov-Dec;71(6):1051-5
24919577 - Phytother Res. 2014 Nov;28(11):1581-8
18167046 - Phytother Res. 2008 Apr;22(4):455-7
10844978 - Indian J Biochem Biophys. 1999 Oct;36(5):299-304
12010007 - J Agric Food Chem. 2002 May 22;50(11):3337-40
18954071 - J Agric Food Chem. 2008 Nov 26;56(22):10544-51
18486125 - Eur J Pharmacol. 2008 Jun 10;587(1-3):25-34
12628515 - Mutat Res. 2003 Feb-Mar;523-524:173-82
17132211 - J Pharm Pharmacol. 2006 Nov;58(11):1483-90
27422505 - Adv Nutr. 2016 Jul 15;7(4):706-18
25548801 - Cell Mol Life Sci. 2015 Apr;72(8):1473-88
24240809 - Int J Mol Sci. 2013 Nov 14;14(11):22483-98
18085528 - Mol Carcinog. 2008 Mar;47(3):184-96
19481462 - Bioorg Med Chem. 2009 Jul 1;17(13):4510-22
23921149 - Toxicol Appl Pharmacol. 2013 Nov 1;272(3):746-56
17404060 - Ann N Y Acad Sci. 2007 Jan;1095:473-82
15465334 - Bioorg Med Chem. 2004 Nov 1;12(21):5571-8
22240353 - Clin Hemorheol Microcirc. 2012;50(3):179-87
14760392 - Br J Cancer. 2004 Feb 9;90(3):736-44
7550091 - Biol Pharm Bull. 1995 Mar;18(3):401-6
22210049 - Prostaglandins Other Lipid Mediat. 2012 Aug;98(3-4):69-74
22088434 - Am J Physiol Renal Physiol. 2012 Feb 15;302(4):F408-20
14705880 - J Agric Food Chem. 2003 Jul 30;51(16):4576-84
17449884 - J Antimicrob Chemother. 2007 Jun;59(6):1182-4
19251420 - Bioorg Med Chem. 2009 Mar 15;17(6):2360-5
18381677 - Mol Nutr Food Res. 2008 Apr;52(4):408-18
17869087 - J Nutr Biochem. 2008 Jul;19(7):459-66
25865632 - Exp Dermatol. 2015 Aug;24(8):632-4
20554604 - Mol Pharmacol. 2010 Sep;78(3):466-77
19591809 - Biochem Pharmacol. 2009 Nov 1;78(9):1224-32
22707295 - Cell Biochem Biophys. 2012 Nov;64(2):101-6
23246837 - Biochem Biophys Res Commun. 2013 Jan 18;430(3):1164-8
22828135 - Carcinogenesis. 2012 Nov;33(11):2172-80
27048088 - Postepy Biochem. 2015;61(4):336-43
21557933 - Biochem Biophys Res Commun. 2011 Jul 15;410(4):707-13
22326393 - Bioorg Med Chem Lett. 2012 Mar 1;22(5):2114-8
24492474 - J Cardiovasc Pharmacol. 2014 Jun;63(6):567-76
25476892 - Biochim Biophys Acta. 2015 Feb;1853(2):377-87
25315298 - Biochim Biophys Acta. 2015 Jun;1852(6):1114-23
26344592 - Bioorg Med Chem. 2015 Oct 1;23(19):6355-63
25111660 - Food Chem Toxicol. 2014 Oct;72 :303-11
21928089 - Apoptosis. 2012 Jan;17 (1):25-36
19887493 - Cardiovasc Res. 2010 Mar 1;85(4):836-44
25989218 - J Med Virol. 2015 Dec;87(12):2054-60
23808710 - Crit Rev Clin Lab Sci. 2013 May-Jun;50(3):65-78
21261636 - Ann N Y Acad Sci. 2011 Jan;1215:9-15
17287390 - Drug Metab Dispos. 2007 May;35(5):699-703
23560895 - J Agric Food Chem. 2013 May 8;61(18):4326-35
20014068 - J Cell Biochem. 2010 Feb 1;109(2):339-46
21229986 - J Agric Food Chem. 2011 Feb 23;59(4):1072-7
20558128 - Arch Biochem Biophys. 2010 Sep 1;501(1):142-50
28178690 - Oncotarget. 2017 Jun 20;8(25):40289-40304
12298009 - Chemistry. 2002 Sep 16;8(18):4191-8
19956188 - J Invest Dermatol. 2010 Jun;130(6):1668-79
24070177 - BMC Complement Altern Med. 2013 Sep 26;13:238
27081659 - Ann Clin Transl Neurol. 2016 Mar 02;3(4):288-94
23567244 - Food Chem Toxicol. 2013 Nov;61:112-20
26380517 - Pharmazie. 2015 Aug;70(8):501-6
25489419 - Biomol Ther (Seoul). 2014 Nov;22(6):519-24
19488981 - Biomed Chromatogr. 2009 Dec;23 (12 ):1308-15
19016770 - Cancer Sci. 2008 Oct;99(10):2083-96
16982330 - Exp Hematol. 2006 Oct;34(10):1377-84
24329932 - Med Chem. 2014 May;10(3):237-45
24211137 - Chem Biol. 2013 Nov 21;20(11):1375-85
14749471 - Mol Cancer Ther. 2004 Jan;3(1):11-20
23010273 - Bioorg Med Chem Lett. 2012 Nov 1;22(21):6642-6
26921129 - Eur J Pharmacol. 2016 Apr 5;776:26-33
15309446 - Eur J Nutr. 2004 Oct;43(5):275-84
25998136 - Anal Bioanal Chem. 2015 Jul;407(19):5793-801
11719446 - Cancer Res. 2001 Nov 15;61(22):8164-70
18497974 - Oncol Rep. 2008 Jun;19(6):1621-6
22099605 - J Surg Res. 2012 Apr;173(2):e53-61
15703378 - Mol Pharmacol. 2005 May;67(5):1451-9
21261641 - Ann N Y Acad Sci. 2011 Jan;1215:48-59
25686711 - J Agric Food Chem. 2015 Mar 11;63(9):2432-41
23691264 - Oxid Med Cell Longev. 2013;2013:575482
16083495 - BMC Cancer. 2005 Aug 05;5:97
23465317 - Nutr Metab Cardiovasc Dis. 2013 Nov;23(11):1086-92
20232118 - Pharm Res. 2010 Jun;27(6):1042-8
21982274 - Neurobiol Aging. 2012 Sep;33(9):2062-71
20385705 - Hum Exp Toxicol. 2011 Feb;30(2):138-44
23770989 - Acta Pharmacol Sin. 2013 Sep;34(9):1174-82
26722037 - Anticancer Res. 2016 Jan;36(1):137-48
28322972 - Pharmacol Ther. 2017 Oct;178:18-30
18434081 - Toxicol In Vitro. 2008 Aug;22(5):1361-70
21907522 - J Pharm Biomed Anal. 2012 Jan 5;57:94-8
12033810 - J Agric Food Chem. 2002 Jun 5;50(12 ):3453-7
23193425 - Evid Based Complement Alternat Med. 2012;2012:603678
25652123 - Biochim Biophys Acta. 2015 Jun;1852(6):1071-113
22953849 - Food Chem. 2012 Dec 1;135(3):1239-44
24522554 - Mol Cell Biochem. 2014 Jun;391(1-2):27-35
21688389 - Mol Nutr Food Res. 2011 Aug;55(8):1129-41
18664717 - J Lipid Res. 2008 Dec;49(12 ):2571-81
19463925 - Toxicol Lett. 2009 Aug 25;189(1):84-9
21261655 - Ann N Y Acad Sci. 2011 Jan;1215:161-9
19496085 - Mol Nutr Food Res. 2009 Jul;53(7):845-58
27498704 - Int J Oncol. 2016 Oct;49(4):1305-14
22254182 - Am J Cardiovasc Dis. 2011;1(1):16-30
11823594 - J Nutr. 2002 Feb;132(2):298-302
21325831 - Cell Physiol Biochem. 2011;27(2):139-48
20580678 - Int J Biochem Cell Biol. 2010 Sep;42(9):1498-506
19072741 - Mol Nutr Food Res. 2009 Mar;53(3):407-16
17763870 - Parasitol Res. 2007 Dec;102(1):91-7
17696482 - J Agric Food Chem. 2007 Sep 19;55(19):7777-85
15853379 - J Agric Food Chem. 2005 May 4;53(9):3403-7
544512 - Hypertension. 1979 Jan-Feb;1(1):31-8
15748702 - Biochem Pharmacol. 2005 Mar 15;69(6):903-12
24398169 - Chem Biol Interact. 2014 Feb 25;209:96-110
20590626 - Br J Pharmacol. 2010 Jul;160(6):1352-61
23213463 - Biol Open. 2012 Aug 15;1(8):705-10
19487074 - Cancer Lett. 2009 Nov 28;285(2):166-73
15773817 - Biochem J. 2005 Jul 15;389(Pt 2):259-68
19916542 - J Agric Food Chem. 2010 Jan 13;58(1):226-34
19081693 - J Pharm Biomed Anal. 2009 Feb 20;49(2):387-92
28675763 - Ann N Y Acad Sci. 2017 Sep;1403(1):27-37
References_xml – volume: 59
  start-page: 1072
  year: 2011
  ident: ref_63
  article-title: Quantification of trans-3,4,5,4′-tetramethoxystilbene in rat plasma by HPLC: Application to pharmacokinetic study
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/jf1043019
– volume: 1095
  start-page: 473
  year: 2007
  ident: ref_127
  article-title: Protective effects of piceatannol against beta-amyloid-induced neuronal cell death
  publication-title: Ann. N. Y. Acad. Sci.
  doi: 10.1196/annals.1397.051
– volume: 63
  start-page: 27
  year: 2008
  ident: ref_62
  article-title: Resveratrol analog trans 3,4,5,4'-tetramethoxystilbene (DMU-212) mediates anti-tumor effects via mechanism different from that of resveratrol
  publication-title: Cancer Chemother. Pharmacol.
  doi: 10.1007/s00280-008-0704-z
– volume: 28
  start-page: 1581
  year: 2014
  ident: ref_101
  article-title: A review of the pharmacological effects of piceatannol on cardiovascular diseases
  publication-title: Phytother. Res.
  doi: 10.1002/ptr.5185
– volume: 135
  start-page: 1239
  year: 2012
  ident: ref_24
  article-title: Hypohalous acid-mediated halogenation of resveratrol and its role in antioxidant and antimicrobial activities
  publication-title: Food Chem.
  doi: 10.1016/j.foodchem.2012.05.043
– volume: 27
  start-page: 139
  year: 2011
  ident: ref_128
  article-title: Regulation of serotonin transport in human platelets by tyrosine kinase syk
  publication-title: Cell. Physiol. Biochem.
  doi: 10.1159/000325216
– volume: 33
  start-page: 2062
  year: 2012
  ident: ref_44
  article-title: Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and alzheimer’s disease
  publication-title: Neurobiol. Aging
  doi: 10.1016/j.neurobiolaging.2011.08.015
– volume: 49
  start-page: 1305
  year: 2016
  ident: ref_65
  article-title: The resveratrol analogue, 3,4,5,4′-trans-tetramethoxystilbene, inhibits the growth of a375 melanoma cells through multiple anticancer modes of action
  publication-title: Int. J. Oncol.
  doi: 10.3892/ijo.2016.3635
– volume: 43
  start-page: 275
  year: 2004
  ident: ref_110
  article-title: The grape and wine polyphenol piceatannol is a potent inducer of apoptosis in human sk-mel-28 melanoma cells
  publication-title: Eur. J. Nutr.
  doi: 10.1007/s00394-004-0471-5
– volume: 55
  start-page: 7777
  year: 2007
  ident: ref_35
  article-title: Pterostilbene induces apoptosis and cell cycle arrest in human gastric carcinoma cells
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/jf071520h
– volume: 102
  start-page: 91
  year: 2007
  ident: ref_122
  article-title: In vitro antileishmanial activity of resveratrol and its hydroxylated analogues against leishmania major promastigotes and amastigotes
  publication-title: Parasitol. Res.
  doi: 10.1007/s00436-007-0729-y
– volume: 3
  start-page: 11
  year: 2004
  ident: ref_113
  article-title: Signal transducer and activator of transcription 3 (STAT3) activation in prostate cancer: Direct STAT3 inhibition induces apoptosis in prostate cancer lines
  publication-title: Mol. Cancer Ther.
  doi: 10.1158/1535-7163.11.3.1
– volume: 3
  start-page: 288
  year: 2016
  ident: ref_126
  article-title: Antioxidants inhibit neuronal toxicity in parkinson’s disease-linked LRRK2
  publication-title: Ann. Clin. Transl. Neurol.
  doi: 10.1002/acn3.282
– volume: 57
  start-page: 5235
  year: 2009
  ident: ref_53
  article-title: Mechanisms of apoptotic effects induced by resveratrol, dibenzoylmethane, and their analogues on human lung carcinoma cells
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/jf900531m
– volume: 109
  start-page: 339
  year: 2010
  ident: ref_59
  article-title: Resveratrol derivative, trans-3,5,4′-trimethoxystilbene, exerts antiangiogenic and vascular-disrupting effects in zebrafish through the downregulation of VEGFR2 and cell-cycle modulation
  publication-title: J. Cell. Biochem.
  doi: 10.1002/jcb.22405
– volume: 299
  start-page: H1891
  year: 2010
  ident: ref_78
  article-title: 2,3′,4,5′-tetramethoxystilbene prevents deoxycorticosterone-salt-induced hypertension: Contribution of cytochrome P450 1B1
  publication-title: Am. J. physiol.
– volume: 98
  start-page: 69
  year: 2012
  ident: ref_77
  article-title: Contribution of cytochrome P450 1B1 to hypertension and associated pathophysiology: A novel target for antihypertensive agents
  publication-title: Prostaglandins Other Lip. Mediat.
  doi: 10.1016/j.prostaglandins.2011.12.003
– volume: 2013
  start-page: 575482
  year: 2013
  ident: ref_30
  article-title: A review of pterostilbene antioxidant activity and disease modification
  publication-title: Oxidative Med. Cell. Longev.
  doi: 10.1155/2013/575482
– volume: 22
  start-page: 519
  year: 2014
  ident: ref_69
  article-title: Role of annexin a5 on mitochondria-dependent apoptosis induced by tetramethoxystilbene in human breast cancer cells
  publication-title: Biomol. Ther.
  doi: 10.4062/biomolther.2014.112
– volume: 87
  start-page: 2054
  year: 2015
  ident: ref_139
  article-title: A resveratrol analog termed 3,3′,4,4′,5,5′-hexahydroxy-trans-stilbene is a potent HIV-1 inhibitor
  publication-title: J. Med. Virol.
  doi: 10.1002/jmv.24271
– volume: 63
  start-page: 2432
  year: 2015
  ident: ref_36
  article-title: Targeting cancer stem cells in breast cancer: Potential anticancer properties of 6-shogaol and pterostilbene
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/acs.jafc.5b00002
– volume: 1
  start-page: 31
  year: 1979
  ident: ref_76
  article-title: The importance of vasopressin in the development and maintenance of doc-salt hypertension in the rat
  publication-title: Hypertension
  doi: 10.1161/01.HYP.1.1.31
– volume: 53
  start-page: 693
  year: 2010
  ident: ref_50
  article-title: Determination of Z-3,5,4′-trimethoxystilbene in rat plasma by a simple HPLC method: Application in a pre-clinical pharmacokinetic study
  publication-title: J. Pharm. Biomed. Anal.
  doi: 10.1016/j.jpba.2010.03.028
– volume: 410
  start-page: 707
  year: 2011
  ident: ref_143
  article-title: Mechanisms of transthyretin cardiomyocyte toxicity inhibition by resveratrol analogs
  publication-title: Biochem. Biophys. Res. Commun.
  doi: 10.1016/j.bbrc.2011.04.133
– volume: 23
  start-page: 1086
  year: 2013
  ident: ref_92
  article-title: Anti-estrogenic activity of a human resveratrol metabolite
  publication-title: Nutr. Metab. Cardiovasc. Dis.
  doi: 10.1016/j.numecd.2013.01.002
– volume: 58
  start-page: 1443
  year: 2006
  ident: ref_100
  article-title: Pharmacokinetics of selected stilbenes: Rhapontigenin, piceatannol and pinosylvin in rats
  publication-title: J. Pharm. Pharmaco.
  doi: 10.1211/jpp.58.11.0004
– volume: 1852
  start-page: 1071
  year: 2015
  ident: ref_8
  article-title: The pharmacology of resveratrol in animals and humans
  publication-title: Biochim. Biophys. Acta
  doi: 10.1016/j.bbadis.2015.01.014
– volume: 19
  start-page: 1621
  year: 2008
  ident: ref_133
  article-title: Novel resveratrol analogs induce apoptosis and cause cell cycle arrest in HT29 human colon cancer cells: Inhibition of ribonucleotide reductase activity
  publication-title: Oncol. Rep.
– volume: 64
  start-page: 101
  year: 2012
  ident: ref_57
  article-title: Effects of trimethoxystilbene on proliferation and apoptosis of pulmonary artery smooth muscle cells
  publication-title: Cell Biochem. Biophys.
  doi: 10.1007/s12013-012-9377-7
– volume: 189
  start-page: 84
  year: 2009
  ident: ref_73
  article-title: Potent inhibition of human cytochrome P450 1B1 by tetramethoxystilbene
  publication-title: Toxicol. Lett.
  doi: 10.1016/j.toxlet.2009.05.005
– volume: 18
  start-page: 401
  year: 1995
  ident: ref_96
  article-title: Effects of phosphoramidon on endothelin-1 and big endothelin-1 production in human aortic endothelial cells
  publication-title: Biol. Pharm. Bull.
  doi: 10.1248/bpb.18.401
– volume: 61
  start-page: 112
  year: 2013
  ident: ref_43
  article-title: Resveratrol and related stilbenes: Their anti-aging and anti-angiogenic properties
  publication-title: Food Chem. Toxicol.
  doi: 10.1016/j.fct.2013.03.038
– volume: 2012
  start-page: 603678
  year: 2012
  ident: ref_107
  article-title: Antioxidant activities of stilbenoids from rheum emodi wall
  publication-title: Evid. Based Complement. Altern. Med.
  doi: 10.1155/2012/603678
– volume: 85
  start-page: 836
  year: 2010
  ident: ref_103
  article-title: Phosphoinositide 3-kinase is a novel target of piceatannol for inhibiting PDGF-BB-induced proliferation and migration in human aortic smooth muscle cells
  publication-title: Cardiovasc. Res.
  doi: 10.1093/cvr/cvp359
– volume: 27
  start-page: 1042
  year: 2010
  ident: ref_15
  article-title: Resveratrol and resveratrol analogues—Structure-activity relationship
  publication-title: Pharm. Res.
  doi: 10.1007/s11095-010-0090-1
– volume: 776
  start-page: 26
  year: 2016
  ident: ref_41
  article-title: Restoration of sirt1 function by pterostilbene attenuates hypoxia-reoxygenation injury in cardiomyocytes
  publication-title: Eur. J. Pharmacol.
  doi: 10.1016/j.ejphar.2016.02.052
– volume: 14
  start-page: 1173
  year: 2011
  ident: ref_95
  article-title: Structure-activity relationship of resveratrol and its analogue, 4,4′-dihydroxy-trans-stilbene, toward the endothelin axis in human endothelial cells
  publication-title: J. Med. Food
  doi: 10.1089/jmf.2010.0272
– volume: 523–524
  start-page: 173
  year: 2003
  ident: ref_75
  article-title: Cytochrome P450 1B1: A target for inhibition in anticarcinogenesis strategies
  publication-title: Mutat. Res.
– volume: 36
  start-page: 137
  year: 2016
  ident: ref_87
  article-title: Antitumor and antimetastatic activity of synthetic hydroxystilbenes through inhibition of lymphangiogenesis and M2 macrophage differentiation of tumor-associated macrophages
  publication-title: Anticancer Res.
– volume: 72
  start-page: 1473
  year: 2015
  ident: ref_13
  article-title: Metabolic effects of resveratrol: Addressing the controversies
  publication-title: Cell. Mol. Life Sci.
  doi: 10.1007/s00018-014-1808-8
– volume: 391
  start-page: 27
  year: 2014
  ident: ref_70
  article-title: 3,4,5,4′-trans-tetramethoxystilbene (DMU-212) modulates the activation of NF-κB, AP-1, and STAT3 transcription factors in rat liver carcinogenesis induced by initiation-promotion regimen
  publication-title: Mol. Cell. Biochem.
  doi: 10.1007/s11010-014-1983-9
– volume: 35
  start-page: 699
  year: 2007
  ident: ref_117
  article-title: Resveratrol in human hepatoma HepG2 cells: Metabolism and inducibility of detoxifying enzymes
  publication-title: Drug Metab. Dispos. Boil. Fate Chem.
  doi: 10.1124/dmd.106.013664
– volume: 15
  start-page: 76
  year: 2009
  ident: ref_129
  article-title: Comparative neuroprotective properties of stilbene and catechin analogs: Action via a plasma membrane receptor site?
  publication-title: CNS Neurosci. Ther.
  doi: 10.1111/j.1755-5949.2008.00074.x
– volume: 7
  start-page: 706
  year: 2016
  ident: ref_4
  article-title: Resveratrol: How much wine do you have to drink to stay healthy?
  publication-title: Adv. Nutr.
  doi: 10.3945/an.115.011627
– volume: 17
  start-page: 25
  year: 2012
  ident: ref_40
  article-title: Pterostilbene protects vascular endothelial cells against oxidized low-density lipoprotein-induced apoptosis in vitro and in vivo
  publication-title: Apoptosis Int. J. Program. Cell Death
  doi: 10.1007/s10495-011-0653-6
– volume: 37
  start-page: 418
  year: 1999
  ident: ref_123
  article-title: Inhibitory effect of piceatannol, a protein tyrosine kinase inhibitor, on asexual maturation of plasmodium falciparum
  publication-title: Indian J. Exp. Boil.
– volume: 62
  start-page: 2541
  year: 2014
  ident: ref_99
  article-title: Absorption and metabolism of piceatannol in rats
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/jf404694y
– volume: 71
  start-page: 1051
  year: 2014
  ident: ref_32
  article-title: In vitro evaluation of antiproliferative and cytotoxic properties of pterostilbene against human colon cancer cells
  publication-title: Acta Pol. Pharm.
– volume: 1
  start-page: 16
  year: 2011
  ident: ref_102
  article-title: Control of eotaxin-1 expression and release by resveratrol and its metabolites in culture human pulmonary artery endothelial cells
  publication-title: Am. J. Cardiovasc. Dis.
– volume: 36
  start-page: 299
  year: 1999
  ident: ref_124
  article-title: Inhibition of a protein tyrosine kinase activity in plasmodium falciparum by chloroquine
  publication-title: Indian J. Biochem. Biophys.
– volume: 68
  start-page: 397
  year: 2014
  ident: ref_68
  article-title: Dmu-212 inhibits tumor growth in xenograft model of human ovarian cancer
  publication-title: Biomed. Pharmacother.
  doi: 10.1016/j.biopha.2014.02.001
– volume: 52
  start-page: 408
  year: 2008
  ident: ref_116
  article-title: The grape and wine constituent piceatannol inhibits proliferation of human bladder cancer cells via blocking cell cycle progression and inducing FAS/membrane bound FAS ligand-mediated apoptotic pathway
  publication-title: Mol. Nutr. Food Res.
  doi: 10.1002/mnfr.200700252
– volume: 42
  start-page: 1498
  year: 2010
  ident: ref_119
  article-title: Piceatannol induces Fas and Fasl up-regulation in human leukemia U937 cells via Ca2+/p38α MAPK-mediated activation of c-JUN and ATF-2 pathways
  publication-title: Int. J. Biochem. Cell Biol.
  doi: 10.1016/j.biocel.2010.05.007
– volume: 22
  start-page: 1361
  year: 2008
  ident: ref_132
  article-title: Cytotoxic activity of 3,3′,4,4′,5,5′-hexahydroxystilbene against breast cancer cells is mediated by induction of p53 and downregulation of mitochondrial superoxide dismutase
  publication-title: Toxicol. In Vitro
  doi: 10.1016/j.tiv.2008.03.002
– volume: 67
  start-page: 1987
  year: 2004
  ident: ref_84
  article-title: Potent inhibition of recombinant human cytochrome P-450 1A1 by pentamethoxystilbene
  publication-title: J. Toxicol. Environ. Health Part A
  doi: 10.1080/15287390490514642
– volume: 389
  start-page: 259
  year: 2005
  ident: ref_19
  article-title: Inhibition of mammalian DNA polymerases by resveratrol: Mechanism and structural determinants
  publication-title: Biochem. J.
  doi: 10.1042/BJ20050094
– volume: 1215
  start-page: 161
  year: 2011
  ident: ref_10
  article-title: Clinical trials of resveratrol
  publication-title: Ann. N. Y. Acad. Sci.
  doi: 10.1111/j.1749-6632.2010.05853.x
– volume: 194
  start-page: 178
  year: 2014
  ident: ref_137
  article-title: Recent advances of resveratrol in nanostructured based delivery systems and in the management of HIV/aids
  publication-title: J. Control. Release
  doi: 10.1016/j.jconrel.2014.09.002
– volume: 78
  start-page: 466
  year: 2010
  ident: ref_85
  article-title: Resveratrol protects dopamine neurons against lipopolysaccharide-induced neurotoxicity through its anti-inflammatory actions
  publication-title: Mol. Pharmacol.
  doi: 10.1124/mol.110.064535
– volume: 51
  start-page: 4576
  year: 2003
  ident: ref_111
  article-title: Grape polyphenol resveratrol and the related molecule 4-hydroxystilbene induce growth inhibition, apoptosis, s-phase arrest, and upregulation of cyclins A, E, and B1 in human Sk-Mel-28 melanoma cells
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/jf030073c
– volume: 58
  start-page: 1483
  year: 2006
  ident: ref_48
  article-title: The antioxidant role of pterostilbene in streptozotocin-nicotinamide-induced type 2 diabetes mellitus in wistar rats
  publication-title: J. Pharm. Pharmacol.
  doi: 10.1211/jpp.58.11.0009
– volume: 49
  start-page: 2571
  year: 2008
  ident: ref_112
  article-title: Ceramide accelerates ultraviolet-induced MMP-1 expression through jak1/stat-1 pathway in cultured human dermal fibroblasts
  publication-title: J. Lip. Res.
  doi: 10.1194/jlr.M800112-JLR200
– volume: 1215
  start-page: 9
  year: 2011
  ident: ref_11
  article-title: Bioavailability of resveratrol
  publication-title: Ann. N. Y. Acad. Sci.
  doi: 10.1111/j.1749-6632.2010.05842.x
– volume: 58
  start-page: 226
  year: 2010
  ident: ref_81
  article-title: 3,5,3′,4′,5′-pentamethoxystilbene (MR-5), a synthetically methoxylated analogue of resveratrol, inhibits growth and induces G1 cell cycle arrest of human breast carcinoma MCF-7 cells
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/jf903067g
– volume: 22
  start-page: 455
  year: 2008
  ident: ref_121
  article-title: Antileishmanial activity of piceatannol isolated from euphorbia lagascae seeds
  publication-title: Phytother. Res.
  doi: 10.1002/ptr.2334
– volume: 302
  start-page: F408
  year: 2012
  ident: ref_79
  article-title: Involvement of cytochrome P-450 1B1 in renal dysfunction, injury, and inflammation associated with angiotensin ii-induced hypertension in rats
  publication-title: Am. J. physiol.
– volume: 30
  start-page: 138
  year: 2011
  ident: ref_29
  article-title: Cytotoxic and antioxidant effects of methoxylated stilbene analogues on HepG2 hepatoma and chang liver cells: Implications for structure activity relationship
  publication-title: Hum. Exp. Toxicol.
  doi: 10.1177/0960327110368739
– volume: 30
  start-page: 1234
  year: 2009
  ident: ref_33
  article-title: Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells
  publication-title: Carcinogenesis
  doi: 10.1093/carcin/bgp121
– volume: 1403
  start-page: 27
  year: 2017
  ident: ref_1
  article-title: Resveratrol derivatives as a pharmacological tool
  publication-title: Ann. N. Y. Acad. Sci.
  doi: 10.1111/nyas.13401
– volume: 53
  start-page: 3403
  year: 2005
  ident: ref_49
  article-title: Pterostilbene, a new agonist for the peroxisome proliferator-activated receptor alpha-isoform, lowers plasma lipoproteins and cholesterol in hypercholesterolemic hamsters
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/jf0580364
– volume: 34
  start-page: 1377
  year: 2006
  ident: ref_136
  article-title: Cytotoxic and biochemical effects of 3,3′,4,4′,5,5′-hexahydroxystilbene, a novel resveratrol analog in HL-60 human promyelocytic leukemia cells
  publication-title: Exp. Hematol.
  doi: 10.1016/j.exphem.2006.05.018
– volume: 76
  start-page: 4887
  year: 2016
  ident: ref_61
  article-title: (Z)-3,5,4′-trimethoxystilbene limits hepatitis c and cancer pathophysiology by blocking microtubule dynamics and cell-cycle progression
  publication-title: Cancer Res.
  doi: 10.1158/0008-5472.CAN-15-2722
– volume: 1215
  start-page: 48
  year: 2011
  ident: ref_16
  article-title: Transport, stability, and biological activity of resveratrol
  publication-title: Ann. N. Y. Acad. Sci.
  doi: 10.1111/j.1749-6632.2010.05871.x
– volume: 59
  start-page: 1182
  year: 2007
  ident: ref_125
  article-title: Resveratrol inhibition of propionibacterium acnes
  publication-title: J. Antimicrob. Chemother.
  doi: 10.1093/jac/dkm099
– volume: 20
  start-page: 1375
  year: 2013
  ident: ref_142
  article-title: Crystal structures of Sirt3 complexes with 4′-bromo-resveratrol reveal binding sites and inhibition mechanism
  publication-title: Chem. Boil.
  doi: 10.1016/j.chembiol.2013.09.019
– volume: 130
  start-page: 1668
  year: 2010
  ident: ref_135
  article-title: 3,3′,4,4′,5,5′-hexahydroxystilbene impairs melanoma progression in a metastatic mouse model
  publication-title: J. Invest. Dermatol.
  doi: 10.1038/jid.2009.376
– volume: 12
  start-page: 5571
  year: 2004
  ident: ref_131
  article-title: Resveratrol analogues as selective cyclooxygenase-2 inhibitors: Synthesis and structure-activity relationship
  publication-title: Bioorg. Med. Chem.
  doi: 10.1016/j.bmc.2004.08.008
– volume: 8
  start-page: 40289
  year: 2017
  ident: ref_12
  article-title: Differential sensitivities of bladder cancer cell lines to resveratol are unrelated to its metabolic profile
  publication-title: Oncotarget.
  doi: 10.18632/oncotarget.15041
– volume: 178
  start-page: 18
  year: 2017
  ident: ref_74
  article-title: Potential role of CYP1B1 in the development and treatment of metabolic diseases
  publication-title: Pharmacol. Ther.
  doi: 10.1016/j.pharmthera.2017.03.007
– volume: 90
  start-page: 736
  year: 2004
  ident: ref_64
  article-title: Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4′-tetramethoxystilbene
  publication-title: Br. J. Cancer
  doi: 10.1038/sj.bjc.6601568
– volume: 69
  start-page: 903
  year: 2005
  ident: ref_22
  article-title: Antioxidant, prooxidant and cytotoxic activity of hydroxylated resveratrol analogues: Structure-activity relationship
  publication-title: Biochem. Pharm.
  doi: 10.1016/j.bcp.2004.12.001
– volume: 17
  start-page: 2360
  year: 2009
  ident: ref_94
  article-title: 4,4′-dihydroxy-trans-stilbene, a resveratrol analogue, exhibited enhanced antioxidant activity and cytotoxicity
  publication-title: Bioorg. Med. Chem.
  doi: 10.1016/j.bmc.2009.02.014
– volume: 19
  start-page: 459
  year: 2008
  ident: ref_109
  article-title: Piceatannol attenuates hydrogen-peroxide- and peroxynitrite-induced apoptosis of PC12 cells by blocking down-regulation of Bcl-XL and activation of JNK
  publication-title: J. Nutr. Biochem.
  doi: 10.1016/j.jnutbio.2007.06.001
– volume: 14
  start-page: 22483
  year: 2013
  ident: ref_130
  article-title: Synthetic resveratrol analogue, 3,3′,4,4′,5,5′-hexahydroxy-trans-stilbene, accelerates senescence in peritoneal mesothelium and promotes senescence-dependent growth of gastrointestinal cancers
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms141122483
– volume: 34
  start-page: 1174
  year: 2013
  ident: ref_67
  article-title: Trans-3,4,5,4′-tetramethoxystilbene, a resveratrol analog, potently inhibits angiogenesis in vitro and in vivo
  publication-title: Acta Pharmacol. Sin.
  doi: 10.1038/aps.2013.60
– volume: 173
  start-page: e53
  year: 2012
  ident: ref_31
  article-title: Pterostilbene and cancer: Current review
  publication-title: J. Surg. Res.
  doi: 10.1016/j.jss.2011.09.054
– volume: 23
  start-page: 6355
  year: 2015
  ident: ref_144
  article-title: Deprotometalation-iodolysis and computed CH acidity of 1,2,3- and 1,2,4-triazoles. Application to the synthesis of resveratrol analogues
  publication-title: Bioorg. Med. Chem.
  doi: 10.1016/j.bmc.2015.08.031
– volume: 789
  start-page: 229
  year: 2016
  ident: ref_25
  article-title: Promising therapeutic potential of pterostilbene and its mechanistic insight based on preclinical evidence
  publication-title: Eur. J. Pharm.
  doi: 10.1016/j.ejphar.2016.07.046
– ident: ref_39
  doi: 10.1186/1472-6882-13-238
– volume: 55
  start-page: 1129
  year: 2011
  ident: ref_7
  article-title: Resveratrol and health—A comprehensive review of human clinical trials
  publication-title: Mol. Nutr. Food Res.
  doi: 10.1002/mnfr.201100143
– volume: 61
  start-page: 336
  year: 2015
  ident: ref_17
  article-title: Biological multifunctionality of resveratrol and its derivatives
  publication-title: Postepy Biochem.
– volume: 70
  start-page: 501
  year: 2015
  ident: ref_14
  article-title: Properties and molecular mechanisms of resveratrol: A review
  publication-title: Die Pharm.
– volume: 160
  start-page: 1352
  year: 2010
  ident: ref_83
  article-title: 2,3′,4,4′,5′-pentamethoxy-trans-stilbene, a resveratrol derivative, inhibits colitis-associated colorectal carcinogenesis in mice
  publication-title: Br. J. Pharmacol.
  doi: 10.1111/j.1476-5381.2010.00785.x
– volume: 587
  start-page: 25
  year: 2008
  ident: ref_71
  article-title: Trans- and cis-stilbene polyphenols induced rapid perinuclear mitochondrial clustering and p53-independent apoptosis in cancer cells but not normal cells
  publication-title: Eur. J. Pharmacol.
  doi: 10.1016/j.ejphar.2008.03.027
– volume: 22
  start-page: 6642
  year: 2012
  ident: ref_138
  article-title: Anti-HIV-1 activity of resveratrol derivatives and synergistic inhibition of HIV-1 by the combination of resveratrol and decitabine
  publication-title: Bioorg. Med. Chem. Lett.
  doi: 10.1016/j.bmcl.2012.08.108
– volume: 22
  start-page: 169
  year: 2008
  ident: ref_26
  article-title: Pharmacometrics of pterostilbene: Preclinical pharmacokinetics and metabolism, anticancer, antiinflammatory, antioxidant and analgesic activity
  publication-title: Phytother. Res. PTR
  doi: 10.1002/ptr.2277
– volume: 72
  start-page: 303
  year: 2014
  ident: ref_45
  article-title: The berry constituents quercetin, kaempferol, and pterostilbene synergistically attenuate reactive oxygen species: Involvement of the Nrf2-ARE signaling pathway
  publication-title: Food Chem. Toxicol.
  doi: 10.1016/j.fct.2014.07.038
– ident: ref_88
  doi: 10.18632/oncotarget.17879
– volume: 67
  start-page: 1451
  year: 2005
  ident: ref_60
  article-title: Antiangiogenic and vascular-targeting activity of the microtubule-destabilizing trans-resveratrol derivative 3,5,4′-trimethoxystilbene
  publication-title: Mol. Pharmacol.
  doi: 10.1124/mol.104.009043
– volume: 50
  start-page: 65
  year: 2013
  ident: ref_21
  article-title: Pterostilbene: Biomedical applications
  publication-title: Crit. Rev. Clin. Lab. Sci.
  doi: 10.3109/10408363.2013.805182
– volume: 272
  start-page: 746
  year: 2013
  ident: ref_52
  article-title: 3,5,4′-trimethoxystilbene, a natural methoxylated analog of resveratrol, inhibits breast cancer cell invasiveness by downregulation of PI3K/Akt and Wnt/beta-catenin signaling cascades and reversal of epithelial-mesenchymal transition
  publication-title: Toxicol. Appl. Pharmacol.
  doi: 10.1016/j.taap.2013.07.019
– volume: 53
  start-page: 407
  year: 2009
  ident: ref_54
  article-title: Resveratrol analog-3,5,4′-trimethoxy-trans-stilbene inhibits invasion of human lung adenocarcinoma cells by suppressing the MAPK pathway and decreasing matrix metalloproteinase-2 expression
  publication-title: Mol. Nutr. Food Res.
  doi: 10.1002/mnfr.200800123
– volume: 24
  start-page: 632
  year: 2015
  ident: ref_66
  article-title: Activation of ERK1/2 is required for the antimitotic activity of the resveratrol analogue 3,4,5,4′-tetramethoxystilbene (DMU-212) in human melanoma cells
  publication-title: Exp. Dermatol.
  doi: 10.1111/exd.12721
– volume: 23
  start-page: 1308
  year: 2009
  ident: ref_27
  article-title: Determination of pterostilbene in rat plasma by a simple HPLC-UV method and its application in pre-clinical pharmacokinetic study
  publication-title: Biomed. Chromatogr.
  doi: 10.1002/bmc.1254
– volume: 57
  start-page: 94
  year: 2012
  ident: ref_80
  article-title: Determination of trans-2,4,3′,4′,5′-pentamethoxystilbene in rat plasma and its application to a pharmacokinetic study
  publication-title: J. Pharm. Biomed. Anal.
  doi: 10.1016/j.jpba.2011.08.020
– volume: 209
  start-page: 96
  year: 2014
  ident: ref_134
  article-title: Effects of hydroxylated resveratrol analogs on oxidative stress and cancer cells death in human acute T cell leukemia cell line: Prooxidative potential of hydroxylated resveratrol analogs
  publication-title: Chem. Boil. Interact.
  doi: 10.1016/j.cbi.2013.12.009
– volume: 61
  start-page: 4326
  year: 2013
  ident: ref_34
  article-title: Long-term ethanol exposure-induced hepatocellular carcinoma cell migration and invasion through lysyl oxidase activation are attenuated by combined treatment with pterostilbene and curcumin analogues
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/jf4004175
– volume: 19
  start-page: 5321
  year: 2011
  ident: ref_20
  article-title: Chemical modifications of resveratrol for improved protein kinase c alpha activity
  publication-title: Bioorg. Med. Chem.
  doi: 10.1016/j.bmc.2011.08.008
– volume: 49
  start-page: 387
  year: 2009
  ident: ref_51
  article-title: A rapid HPLC method for the quantification of 3,5,4′-trimethoxy-trans-stilbene (TMS) in rat plasma and its application in pharmacokinetic study
  publication-title: J. Pharm. Biomed. Anal.
  doi: 10.1016/j.jpba.2008.10.042
– volume: 22
  start-page: 2114
  year: 2012
  ident: ref_55
  article-title: A resveratrol analog, phoyunbene b, induces G2/M cell cycle arrest and apoptosis in HepG2 liver cancer cells
  publication-title: Bioorg. Med. Chem. Lett.
  doi: 10.1016/j.bmcl.2011.12.095
– volume: 1403
  start-page: 15
  year: 2017
  ident: ref_38
  article-title: Resveratrol and pterostilbene as a microrna-mediated chemopreventive and therapeutic strategy in prostate cancer
  publication-title: Ann. N. Y. Acad. Sci.
  doi: 10.1111/nyas.13372
– volume: 10
  start-page: 237
  year: 2014
  ident: ref_5
  article-title: Chemistry, stability and bioavailability of resveratrol
  publication-title: Med. Chem.
  doi: 10.2174/15734064113096660053
– volume: 75
  start-page: 2829
  year: 2004
  ident: ref_141
  article-title: G2/m cell cycle arrest and induction of apoptosis by a stilbenoid, 3,4,5-trimethoxy-4′-bromo-cis-stilbene, in human lung cancer cells
  publication-title: Life Sci.
  doi: 10.1016/j.lfs.2004.07.002
– volume: 34
  start-page: 142
  year: 2006
  ident: ref_97
  article-title: Structure-activity relationship studies of resveratrol and its analogues by the reaction kinetics of low density lipoprotein peroxidation
  publication-title: Bioorg. Chem.
  doi: 10.1016/j.bioorg.2006.04.001
– volume: 41
  start-page: 2493
  year: 2009
  ident: ref_23
  article-title: The resveratrol analogue 4,4′-dihydroxy-trans-stilbene inhibits cell proliferation with higher efficiency but different mechanism from resveratrol
  publication-title: Int. J. Biochem. Cell Boil.
  doi: 10.1016/j.biocel.2009.08.005
– ident: ref_120
  doi: 10.1186/1471-2407-5-97
– volume: 63
  start-page: 567
  year: 2014
  ident: ref_56
  article-title: Inhibition of NOX/VPO1 pathway and inflammatory reaction by trimethoxystilbene in prevention of cardiovascular remodeling in hypoxia-induced pulmonary hypertensive rats
  publication-title: J. Cardiovasc. Pharmacol.
  doi: 10.1097/FJC.0000000000000082
– volume: 407
  start-page: 5793
  year: 2015
  ident: ref_86
  article-title: Determination of naturally occurring resveratrol analog trans-4,4′-dihydroxystilbene in rat plasma by liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study
  publication-title: Anal. Bioanal. Chem.
  doi: 10.1007/s00216-015-8762-7
– volume: 89
  start-page: 227
  year: 2015
  ident: ref_46
  article-title: Effects of pterostilbene and resveratrol on brain and behavior
  publication-title: Neurochem. Int.
  doi: 10.1016/j.neuint.2015.07.017
– volume: 50
  start-page: 179
  year: 2012
  ident: ref_42
  article-title: Cardioprotection by resveratrol: A human clinical trial in patients with stable coronary artery disease
  publication-title: Clin. Hemorheol. Microcirc.
  doi: 10.3233/CH-2011-1424
– volume: 56
  start-page: 10544
  year: 2008
  ident: ref_47
  article-title: Cellular and behavioral effects of stilbene resveratrol analogues: Implications for reducing the deleterious effects of aging
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/jf802279h
– volume: 430
  start-page: 1164
  year: 2013
  ident: ref_104
  article-title: Effect of long-term piceatannol treatment on eNOS levels in cultured endothelial cells
  publication-title: Biochem. Biophys. Res. Commun.
  doi: 10.1016/j.bbrc.2012.12.017
– volume: 8
  start-page: 4191
  year: 2002
  ident: ref_98
  article-title: Antioxidant effects of resveratrol and its analogues against the free-radical-induced peroxidation of linoleic acid in micelles
  publication-title: Chemistry
  doi: 10.1002/1521-3765(20020916)8:18<4191::AID-CHEM4191>3.0.CO;2-S
– volume: 61
  start-page: 8164
  year: 2001
  ident: ref_72
  article-title: A new selective and potent inhibitor of human cytochrome P450 1B1 and its application to antimutagenesis
  publication-title: Cancer Res.
– volume: 112
  start-page: 1813
  year: 2005
  ident: ref_106
  article-title: Role of angiogenesis in cardiovascular disease: A critical appraisal
  publication-title: Circulation
  doi: 10.1161/CIRCULATIONAHA.105.535294
– volume: 50
  start-page: 3453
  year: 2002
  ident: ref_28
  article-title: Cancer chemopreventive and antioxidant activities of pterostilbene, a naturally occurring analogue of resveratrol
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/jf0116855
– volume: 33
  start-page: 2172
  year: 2012
  ident: ref_90
  article-title: The resveratrol analog 4,4′-dihydroxy-trans-stilbene suppresses transformation in normal mouse fibroblasts and inhibits proliferation and invasion of human breast cancer cells
  publication-title: Carcinogenesis
  doi: 10.1093/carcin/bgs244
– volume: 17
  start-page: 4510
  year: 2009
  ident: ref_140
  article-title: Synthesis, structural characterisation and biological evaluation of fluorinated analogues of resveratrol
  publication-title: Bioorg. Med. Chem.
  doi: 10.1016/j.bmc.2009.05.007
– volume: 50
  start-page: 3337
  year: 2002
  ident: ref_3
  article-title: Plant foods and herbal sources of resveratrol
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/jf0112973
– volume: 72
  start-page: 573
  year: 2006
  ident: ref_93
  article-title: Proteasome-independent down-regulation of estrogen receptor-alpha (ERα) in breast cancer cells treated with 4,4′-dihydroxy-trans-stilbene
  publication-title: Biochem. Pharmacol.
  doi: 10.1016/j.bcp.2006.05.023
– volume: 7
  start-page: 37
  year: 2005
  ident: ref_37
  article-title: Association between pterostilbene and quercetin inhibits metastatic activity of B16 melanoma
  publication-title: Neoplasia
  doi: 10.1593/neo.04337
– volume: 53
  start-page: 845
  year: 2009
  ident: ref_91
  article-title: Structure-activity relationships of resveratrol and derivatives in breast cancer cells
  publication-title: Mol. Nutr. Food Res.
  doi: 10.1002/mnfr.200800331
– volume: 1
  start-page: 705
  year: 2012
  ident: ref_105
  article-title: The COP9 signalosome, cullin 3 and Keap1 supercomplex regulates CHOP stability and adipogenesis
  publication-title: Biol. Open
  doi: 10.1242/bio.20121875
– volume: 78
  start-page: 1224
  year: 2009
  ident: ref_82
  article-title: 2,3′,4,4′,5′-pentamethoxy-trans-stilbene, a resveratrol derivative, is a potent inducer of apoptosis in colon cancer cells via targeting microtubules
  publication-title: Biochem. Pharmacol.
  doi: 10.1016/j.bcp.2009.06.109
– volume: 93
  start-page: 522
  year: 2015
  ident: ref_9
  article-title: Proposed trial: Safety and efficacy of resveratrol for the treatment of non-alcoholic fatty liver disease (NAFLD) and associated insulin resistance in adolescents who are overweight or obese adolescents—Rationale and protocol
  publication-title: Biochem. Cell Boil.
  doi: 10.1139/bcb-2014-0136
– volume: 52
  start-page: 148
  year: 2016
  ident: ref_2
  article-title: Multiplicity of effects and health benefits of resveratrol
  publication-title: Medicina
  doi: 10.1016/j.medici.2016.03.003
– volume: 19
  start-page: 961
  year: 2008
  ident: ref_118
  article-title: Induction of apoptosis by piceatannol in human leukemic U937 cells through down-regulation of BCL-2 and activation of caspases
  publication-title: Oncol. Rep.
– volume: 1852
  start-page: 1114
  year: 2015
  ident: ref_6
  article-title: The molecular targets of resveratrol
  publication-title: Biochim. Biophys. Acta
  doi: 10.1016/j.bbadis.2014.10.005
– volume: 285
  start-page: 166
  year: 2009
  ident: ref_114
  article-title: Piceatannol, a natural stilbene from grapes, induces G1 cell cycle arrest in androgen-insensitive DU145 human prostate cancer cells via the inhibition of CDK activity
  publication-title: Cancer Lett.
  doi: 10.1016/j.canlet.2009.05.011
– volume: 99
  start-page: 2083
  year: 2008
  ident: ref_89
  article-title: Antitumor activities of synthetic and natural stilbenes through antiangiogenic action
  publication-title: Cancer Sci.
  doi: 10.1111/j.1349-7006.2008.00948.x
– volume: 1853
  start-page: 377
  year: 2015
  ident: ref_58
  article-title: Novel role for TRPC4 in regulation of macroautophagy by a small molecule in vascular endothelial cells
  publication-title: Biochim. Biophys. Acta
  doi: 10.1016/j.bbamcr.2014.10.030
– volume: 501
  start-page: 142
  year: 2010
  ident: ref_108
  article-title: Piceatannol induces heme oxygenase-1 expression in human mammary epithelial cells through activation of are-driven NRF2 signaling
  publication-title: Arch. Biochem. Biophys.
  doi: 10.1016/j.abb.2010.06.011
– volume: 132
  start-page: 298
  year: 2002
  ident: ref_115
  article-title: Piceatannol, a natural analog of resveratrol, inhibits progression through the s phase of the cell cycle in colorectal cancer cell lines
  publication-title: J. Nutr.
  doi: 10.1093/jn/132.2.298
– volume: 47
  start-page: 184
  year: 2008
  ident: ref_18
  article-title: Antitumor activity of 3,5,4′-trimethoxystilbene in colo 205 cells and xenografts in SCID mice
  publication-title: Mol. Carcinog.
  doi: 10.1002/mc.20352
– reference: 26380517 - Pharmazie. 2015 Aug;70(8):501-6
– reference: 22210049 - Prostaglandins Other Lipid Mediat. 2012 Aug;98(3-4):69-74
– reference: 28178690 - Oncotarget. 2017 Jun 20;8(25):40289-40304
– reference: 26921129 - Eur J Pharmacol. 2016 Apr 5;776:26-33
– reference: 27048088 - Postepy Biochem. 2015;61(4):336-43
– reference: 19916542 - J Agric Food Chem. 2010 Jan 13;58(1):226-34
– reference: 15773817 - Biochem J. 2005 Jul 15;389(Pt 2):259-68
– reference: 18486125 - Eur J Pharmacol. 2008 Jun 10;587(1-3):25-34
– reference: 17287390 - Drug Metab Dispos. 2007 May;35(5):699-703
– reference: 18497974 - Oncol Rep. 2008 Jun;19(6):1621-6
– reference: 21880495 - Bioorg Med Chem. 2011 Sep 15;19(18):5321-33
– reference: 19487074 - Cancer Lett. 2009 Nov 28;285(2):166-73
– reference: 17869087 - J Nutr Biochem. 2008 Jul;19(7):459-66
– reference: 24329932 - Med Chem. 2014 May;10(3):237-45
– reference: 25217813 - J Control Release. 2014 Nov 28;194:178-88
– reference: 24919577 - Phytother Res. 2014 Nov;28(11):1581-8
– reference: 19447859 - Carcinogenesis. 2009 Jul;30(7):1234-42
– reference: 16982330 - Exp Hematol. 2006 Oct;34(10):1377-84
– reference: 23808710 - Crit Rev Clin Lab Sci. 2013 May-Jun;50(3):65-78
– reference: 22099605 - J Surg Res. 2012 Apr;173(2):e53-61
– reference: 17726731 - Phytother Res. 2008 Feb;22(2):169-79
– reference: 27081659 - Ann Clin Transl Neurol. 2016 Mar 02;3(4):288-94
– reference: 19887493 - Cardiovasc Res. 2010 Mar 1;85(4):836-44
– reference: 19488981 - Biomed Chromatogr. 2009 Dec;23 (12 ):1308-15
– reference: 29088756 - Oncotarget. 2017 May 16;8(43):73905-73924
– reference: 12628515 - Mutat Res. 2003 Feb-Mar;523-524:173-82
– reference: 18357382 - Oncol Rep. 2008 Apr;19(4):961-7
– reference: 19591809 - Biochem Pharmacol. 2009 Nov 1;78(9):1224-32
– reference: 24492474 - J Cardiovasc Pharmacol. 2014 Jun;63(6):567-76
– reference: 18085528 - Mol Carcinog. 2008 Mar;47(3):184-96
– reference: 27287718 - Cancer Res. 2016 Aug 15;76(16):4887-96
– reference: 25111660 - Food Chem Toxicol. 2014 Oct;72 :303-11
– reference: 20014068 - J Cell Biochem. 2010 Feb 1;109(2):339-46
– reference: 21554123 - J Med Food. 2011 Oct;14 (10 ):1173-80
– reference: 23567244 - Food Chem Toxicol. 2013 Nov;61:112-20
– reference: 27496184 - Medicina (Kaunas). 2016;52(3):148-55
– reference: 17696482 - J Agric Food Chem. 2007 Sep 19;55(19):7777-85
– reference: 22240353 - Clin Hemorheol Microcirc. 2012;50(3):179-87
– reference: 20554604 - Mol Pharmacol. 2010 Sep;78(3):466-77
– reference: 25686711 - J Agric Food Chem. 2015 Mar 11;63(9):2432-41
– reference: 20232118 - Pharm Res. 2010 Jun;27(6):1042-8
– reference: 28675763 - Ann N Y Acad Sci. 2017 Sep;1403(1):27-37
– reference: 12033810 - J Agric Food Chem. 2002 Jun 5;50(12 ):3453-7
– reference: 25476892 - Biochim Biophys Acta. 2015 Feb;1853(2):377-87
– reference: 15748702 - Biochem Pharmacol. 2005 Mar 15;69(6):903-12
– reference: 26344592 - Bioorg Med Chem. 2015 Oct 1;23(19):6355-63
– reference: 14760392 - Br J Cancer. 2004 Feb 9;90(3):736-44
– reference: 23921149 - Toxicol Appl Pharmacol. 2013 Nov 1;272(3):746-56
– reference: 25865632 - Exp Dermatol. 2015 Aug;24(8):632-4
– reference: 18434081 - Toxicol In Vitro. 2008 Aug;22(5):1361-70
– reference: 17449884 - J Antimicrob Chemother. 2007 Jun;59(6):1182-4
– reference: 27475678 - Eur J Pharmacol. 2016 Oct 15;789:229-243
– reference: 12298009 - Chemistry. 2002 Sep 16;8(18):4191-8
– reference: 23770989 - Acta Pharmacol Sin. 2013 Sep;34(9):1174-82
– reference: 19016770 - Cancer Sci. 2008 Oct;99(10):2083-96
– reference: 21325831 - Cell Physiol Biochem. 2011;27(2):139-48
– reference: 22088434 - Am J Physiol Renal Physiol. 2012 Feb 15;302(4):F408-20
– reference: 17404060 - Ann N Y Acad Sci. 2007 Jan;1095:473-82
– reference: 20590626 - Br J Pharmacol. 2010 Jul;160(6):1352-61
– reference: 19463925 - Toxicol Lett. 2009 Aug 25;189(1):84-9
– reference: 20558128 - Arch Biochem Biophys. 2010 Sep 1;501(1):142-50
– reference: 22953849 - Food Chem. 2012 Dec 1;135(3):1239-44
– reference: 23213463 - Biol Open. 2012 Aug 15;1(8):705-10
– reference: 22326393 - Bioorg Med Chem Lett. 2012 Mar 1;22(5):2114-8
– reference: 17763870 - Parasitol Res. 2007 Dec;102(1):91-7
– reference: 25315298 - Biochim Biophys Acta. 2015 Jun;1852(6):1114-23
– reference: 26722037 - Anticancer Res. 2016 Jan;36(1):137-48
– reference: 23010273 - Bioorg Med Chem Lett. 2012 Nov 1;22(21):6642-6
– reference: 15464834 - Life Sci. 2004 Oct 22;75(23):2829-39
– reference: 7550091 - Biol Pharm Bull. 1995 Mar;18(3):401-6
– reference: 25652123 - Biochim Biophys Acta. 2015 Jun;1852(6):1071-113
– reference: 11823594 - J Nutr. 2002 Feb;132(2):298-302
– reference: 24240809 - Int J Mol Sci. 2013 Nov 14;14(11):22483-98
– reference: 15736313 - Neoplasia. 2005 Jan;7(1):37-47
– reference: 23691264 - Oxid Med Cell Longev. 2013;2013:575482
– reference: 21261655 - Ann N Y Acad Sci. 2011 Jan;1215:161-9
– reference: 18954071 - J Agric Food Chem. 2008 Nov 26;56(22):10544-51
– reference: 22828135 - Carcinogenesis. 2012 Nov;33(11):2172-80
– reference: 18381677 - Mol Nutr Food Res. 2008 Apr;52(4):408-18
– reference: 19081693 - J Pharm Biomed Anal. 2009 Feb 20;49(2):387-92
– reference: 24211137 - Chem Biol. 2013 Nov 21;20(11):1375-85
– reference: 24768110 - Biomed Pharmacother. 2014 May;68(4):397-400
– reference: 24398169 - Chem Biol Interact. 2014 Feb 25;209:96-110
– reference: 22707295 - Cell Biochem Biophys. 2012 Nov;64(2):101-6
– reference: 14749471 - Mol Cancer Ther. 2004 Jan;3(1):11-20
– reference: 20852048 - Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1891-901
– reference: 19441815 - J Agric Food Chem. 2009 Jun 24;57(12):5235-43
– reference: 16822479 - Biochem Pharmacol. 2006 Aug 28;72(5):573-81
– reference: 16172288 - Circulation. 2005 Sep 20;112(12):1813-24
– reference: 20580678 - Int J Biochem Cell Biol. 2010 Sep;42(9):1498-506
– reference: 18664717 - J Lipid Res. 2008 Dec;49(12 ):2571-81
– reference: 18286288 - Cancer Chemother Pharmacol. 2008 Dec;63(1):27-35
– reference: 17132206 - J Pharm Pharmacol. 2006 Nov;58(11):1443-50
– reference: 28662290 - Ann N Y Acad Sci. 2017 Sep;1403(1):15-26
– reference: 21229986 - J Agric Food Chem. 2011 Feb 23;59(4):1072-7
– reference: 25548801 - Cell Mol Life Sci. 2015 Apr;72(8):1473-88
– reference: 15853379 - J Agric Food Chem. 2005 May 4;53(9):3403-7
– reference: 27422505 - Adv Nutr. 2016 Jul 15;7(4):706-18
– reference: 10844978 - Indian J Biochem Biophys. 1999 Oct;36(5):299-304
– reference: 19228181 - CNS Neurosci Ther. 2009 Winter;15(1):76-83
– reference: 22254182 - Am J Cardiovasc Dis. 2011;1(1):16-30
– reference: 15513897 - J Toxicol Environ Health A. 2004 Dec;67(23-24):1987-2000
– reference: 19072741 - Mol Nutr Food Res. 2009 Mar;53(3):407-16
– reference: 24625210 - J Agric Food Chem. 2014 Mar 26;62(12 ):2541-8
– reference: 21982274 - Neurobiol Aging. 2012 Sep;33(9):2062-71
– reference: 15465334 - Bioorg Med Chem. 2004 Nov 1;12(21):5571-8
– reference: 19496085 - Mol Nutr Food Res. 2009 Jul;53(7):845-58
– reference: 11719446 - Cancer Res. 2001 Nov 15;61(22):8164-70
– reference: 23465317 - Nutr Metab Cardiovasc Dis. 2013 Nov;23(11):1086-92
– reference: 25489419 - Biomol Ther (Seoul). 2014 Nov;22(6):519-24
– reference: 21261636 - Ann N Y Acad Sci. 2011 Jan;1215:9-15
– reference: 21688389 - Mol Nutr Food Res. 2011 Aug;55(8):1129-41
– reference: 544512 - Hypertension. 1979 Jan-Feb;1(1):31-8
– reference: 21928089 - Apoptosis. 2012 Jan;17 (1):25-36
– reference: 23560895 - J Agric Food Chem. 2013 May 8;61(18):4326-35
– reference: 26305052 - Biochem Cell Biol. 2015 Oct;93(5):522-30
– reference: 25998136 - Anal Bioanal Chem. 2015 Jul;407(19):5793-801
– reference: 26212523 - Neurochem Int. 2015 Oct;89:227-33
– reference: 25989218 - J Med Virol. 2015 Dec;87(12):2054-60
– reference: 21557933 - Biochem Biophys Res Commun. 2011 Jul 15;410(4):707-13
– reference: 16083495 - BMC Cancer. 2005 Aug 05;5:97
– reference: 21907522 - J Pharm Biomed Anal. 2012 Jan 5;57:94-8
– reference: 19481462 - Bioorg Med Chem. 2009 Jul 1;17(13):4510-22
– reference: 18167046 - Phytother Res. 2008 Apr;22(4):455-7
– reference: 19251420 - Bioorg Med Chem. 2009 Mar 15;17(6):2360-5
– reference: 20385705 - Hum Exp Toxicol. 2011 Feb;30(2):138-44
– reference: 19956188 - J Invest Dermatol. 2010 Jun;130(6):1668-79
– reference: 17132211 - J Pharm Pharmacol. 2006 Nov;58(11):1483-90
– reference: 14705880 - J Agric Food Chem. 2003 Jul 30;51(16):4576-84
– reference: 25745778 - Acta Pol Pharm. 2014 Nov-Dec;71(6):1051-5
– reference: 15309446 - Eur J Nutr. 2004 Oct;43(5):275-84
– reference: 10641182 - Indian J Exp Biol. 1999 Apr;37(4):418-20
– reference: 15703378 - Mol Pharmacol. 2005 May;67(5):1451-9
– reference: 24522554 - Mol Cell Biochem. 2014 Jun;391(1-2):27-35
– reference: 12010007 - J Agric Food Chem. 2002 May 22;50(11):3337-40
– reference: 20427141 - J Pharm Biomed Anal. 2010 Nov 2;53(3):693-7
– reference: 27498704 - Int J Oncol. 2016 Oct;49(4):1305-14
– reference: 19679195 - Int J Biochem Cell Biol. 2009 Dec;41(12):2493-502
– reference: 21261641 - Ann N Y Acad Sci. 2011 Jan;1215:48-59
– reference: 23246837 - Biochem Biophys Res Commun. 2013 Jan 18;430(3):1164-8
– reference: 16712899 - Bioorg Chem. 2006 Jun;34(3):142-57
– reference: 24070177 - BMC Complement Altern Med. 2013 Sep 26;13:238
– reference: 23193425 - Evid Based Complement Alternat Med. 2012;2012:603678
– reference: 28322972 - Pharmacol Ther. 2017 Oct;178:18-30
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Snippet Resveratrol, a natural phytoalexin, exhibits a remarkable range of biological activities, such as anticancer, cardioprotective, neuroprotective and antioxidant...
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StartPage 1188
SubjectTerms Antineoplastic Agents - chemistry
Antineoplastic Agents - pharmacology
antioxidant activity
Antioxidants - chemistry
Antioxidants - pharmacology
Bioavailability
Cardiovascular Agents - chemistry
Cardiovascular Agents - pharmacology
Humans
hydroxylation
medicinal properties
Molecular Structure
Neuroprotective Agents - chemistry
Neuroprotective Agents - pharmacology
phytoalexins
resveratrol
Review
Stilbenes - chemistry
Stilbenes - pharmacology
structure-activity relationships
therapeutics
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Title Therapeutic Versatility of Resveratrol Derivatives
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