Activation of coagulation and hyperfibrinolysis in patients with aortic arch atheromatosis (Aortic AA) as a risk factor for cerebral ischemia

• Published in: Thrombosis and haemostasis Vol. 93; no. 4; p. 690
• Main Authors: Siemens, Hans-Joachim G, Mirau, Wladimir, Brueckner, Sabine, Jahn, Juergen, Roth-Isigkeit, Angela, Gutsche, Sven, Mitusch, Rolf, Sheikhzadeh, Abdolhamid
• Format: Journal Article
• Language: English
• Published: Germany 01.04.2005
• Subjects: Adult; Aged; Aged, 80 and over; Aortic Arch Syndromes - blood; Aortic Arch Syndromes - complications; Arteriosclerosis - blood; Arteriosclerosis - complications; Biomarkers - blood; Blood Coagulation; Brain Ischemia - etiology; Case-Control Studies; Female; Fibrinolysis; Humans; Male; Middle Aged; Risk Factors; Severity of Illness Index; Thrombophilia - blood

In patients with cerebral ischemia, a frequent finding is atheromatous plaques in the ascending aorta and the aortic arch. Since we were able to demonstrate that patients with atrial fibrillation have an increased coagulatory activity, we wanted to evaluate a potential systemic activation of the coa...