Comparison of wavelet and correlation indices of cerebral autoregulation in a pediatric swine model of cardiac arrest

• Published in: Scientific reports Vol. 10; no. 1; p. 5926
• Main Authors: Liu, Xiuyun, Hu, Xiao, Brady, Ken M., Koehler, Raymond, Smielewski, Peter, Czosnyka, Marek, Donnelly, Joseph, Lee, Jennifer K.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 03.04.2020; Nature Publishing Group
• Subjects: 631/378; 692/308; 692/617; Animals; Arterial Pressure - physiology; Blood flow; Blood pressure; Cardiac arrest; Cerebral blood flow; Cerebrovascular Circulation - physiology; Child; Disease Models, Animal; Heart; Heart Arrest - complications; Heart Arrest - physiopathology; Hemoglobin; Hemoglobins - analysis; Homeostasis - physiology; Humanities and Social Sciences; Humans; Hypoxia, Brain - diagnosis; Hypoxia, Brain - etiology; Hypoxia, Brain - physiopathology; Infrared spectroscopy; Intracranial Pressure - physiology; Laser-Doppler Flowmetry; Male; Monitoring methods; multidisciplinary; Neurophysiological Monitoring - methods; Oximetry - methods; Pediatrics; Science; Science (multidisciplinary); Spectroscopy, Near-Infrared; Swine

Existing cerebrovascular blood pressure autoregulation metrics have not been translated to clinical care for pediatric cardiac arrest, in part because signal noise causes high index time-variability. We tested whether a wavelet method that uses near-infrared spectroscopy (NIRS) or intracranial press...