Discovery of potent small-molecule inhibitors of lipoprotein(a) formation - Diaz, Nuria; Perez, Carlos; Escribano, Ana Maria; Sanz, Gema; Priego, Julian; Lafuente, Celia; Barberis, Mario; Calle, Luis; Espinosa, Juan Felix; Priest, Birgit T.; Zhang, Hong Y.; Nosie, Amanda K.; et al. (Nature (London), 2024)
Keywords: 38/77; 631/154/436; 631/535/1266; 64/110; 692/699/75/2099; 82/1; Apolipoprotein B; Apolipoproteins; BASIC BIOLOGICAL SCIENCES; Cardiovascular diseases; Chemical bonds; dyslipidaemias; Health risks; Humanities and Social Sciences; Ligands; Lipoproteins; Low density lipoprotein; Lysine; multidisciplinary; Oral administration; pharmacology; Plasmin; Plasminogen; Proteins; Risk factors; Science; Science (multidisciplinary); Transgenic mice; x-ray crystallography