Emergency Department Management of Sepsis Patients: A Randomized, Goal-Oriented, Noninvasive Sepsis Trial

• Published in: Annals of emergency medicine Vol. 67; no. 3; pp. 367 - 378.e3
• Main Authors: Kuan, Win Sen, MBBS, MRCSEd(A&E), Ibrahim, Irwani, MBBS, FRCSEd(A&E), Leong, Benjamin S.H., MBBS, MRCSEd(A&E), Jain, Swati, MD, Lu, Qingshu, PhD, Cheung, Yin Bun, PhD, Mahadevan, Malcolm, MBBS, FRCSEd(A&E)
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.03.2016
• Subjects: Aged; Critical Care - organization & administration; Disease Management; Emergency; Emergency Service, Hospital - organization & administration; Female; Fluid Therapy - methods; Hospital Costs; Hospital Mortality; Humans; Lactates - blood; Length of Stay - statistics & numerical data; Male; Middle Aged; Monitoring, Physiologic - instrumentation; Organizational Objectives; Sepsis - blood; Sepsis - mortality; Sepsis - therapy; Shock, Septic - blood; Shock, Septic - mortality; Shock, Septic - therapy; Singapore - epidemiology; Stroke Volume; Treatment Outcome; Singapore

Study objective The noninvasive cardiac output monitor and passive leg-raising maneuver has been shown to be reasonably accurate in predicting fluid responsiveness in critically ill patients. We examine whether using a noninvasive protocol would result in more rapid lactate clearance after 3 hours i...