miRTarBase: a database curates experimentally validated microRNA-target interactions

• Published in: Nucleic acids research Vol. 39; no. suppl_1; pp. D163 - D169
• Main Authors: Hsu, Sheng-Da, Lin, Feng-Mao, Wu, Wei-Yun, Liang, Chao, Huang, Wei-Chih, Chan, Wen-Ling, Tsai, Wen-Ting, Chen, Goun-Zhou, Lee, Chia-Jung, Chiu, Chih-Min, Chien, Chia-Hung, Wu, Ming-Chia, Huang, Chi-Ying, Tsou, Ann-Ping, Huang, Hsien-Da
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.01.2011
• Subjects: Computer applications; Data processing; Databases, Nucleic Acid; DNA microarrays; Gene Expression Regulation; MicroRNAs - metabolism; miRNA; non-coding RNA; Reproducibility of Results; RNA Interference; RNA, Messenger - metabolism; Systems Integration; Transcription; User-Computer Interface; Western blotting

MicroRNAs (miRNAs), i.e. small non-coding RNA molecules (~22 nt), can bind to one or more target sites on a gene transcript to negatively regulate protein expression, subsequently controlling many cellular mechanisms. A current and curated collection of miRNA-target interactions (MTIs) with experime...