Sudden unexpected death in Parkinson's disease: Insights from clinical practice
•To reduce the risk of and prevent sudden unexpected death in Parkinson's disease (SUDPAR) translational research and public campaigns are warranted.•Patients with Parkinson's disease should be regularly monitored for cardiac, pulmonary, and autonomic disorders. Classified as the second mo...
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Published in | Clinics (São Paulo, Brazil) Vol. 77; p. 100001 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier España, S.L.U
01.01.2022
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Faculdade de Medicina / USP |
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Abstract | •To reduce the risk of and prevent sudden unexpected death in Parkinson's disease (SUDPAR) translational research and public campaigns are warranted.•Patients with Parkinson's disease should be regularly monitored for cardiac, pulmonary, and autonomic disorders.
Classified as the second most common neurodegenerative disorder associated with aging after Alzheimer's disease, Parkinson's disease (PD) is the most common movement disorder. In the last decade, despite advances in treatment, mortality rates linked with PD continued to reach significant figures. Available studies have shown that compared with healthy controls, patients with PD are accompanied by high rates of premature death. This is usually caused by factors such as pneumonia and cerebrovascular and cardiovascular diseases. Recently, it has been demonstrated that a significant proportion of patients with PD die suddenly. This is referred to as a sudden and unexpected death in PD (SUDPAR). Here, we focus on the magnitude of SUDPAR. Finally, it is important to learn more about SUDPAR for the implementation of effective prevention strategies. |
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AbstractList | •
To reduce the risk of and prevent sudden unexpected death in Parkinson's disease (SUDPAR) translational research and public campaigns are warranted.
•
Patients with Parkinson's disease should be regularly monitored for cardiac, pulmonary, and autonomic disorders.
Classified as the second most common neurodegenerative disorder associated with aging after Alzheimer's disease, Parkinson's disease (PD) is the most common movement disorder. In the last decade, despite advances in treatment, mortality rates linked with PD continued to reach significant figures. Available studies have shown that compared with healthy controls, patients with PD are accompanied by high rates of premature death. This is usually caused by factors such as pneumonia and cerebrovascular and cardiovascular diseases. Recently, it has been demonstrated that a significant proportion of patients with PD die suddenly. This is referred to as a sudden and unexpected death in PD (SUDPAR). Here, we focus on the magnitude of SUDPAR. Finally, it is important to learn more about SUDPAR for the implementation of effective prevention strategies. Classified as the second most common neurodegenerative disorder associated with aging after Alzheimer's disease, Parkinson's disease (PD) is the most common movement disorder. In the last decade, despite advances in treatment, mortality rates linked with PD continued to reach significant figures. Available studies have shown that compared with healthy controls, patients with PD are accompanied by high rates of premature death. This is usually caused by factors such as pneumonia and cerebrovascular and cardiovascular diseases. Recently, it has been demonstrated that a significant proportion of patients with PD die suddenly. This is referred to as a sudden and unexpected death in PD (SUDPAR). Here, we focus on the magnitude of SUDPAR. Finally, it is important to learn more about SUDPAR for the implementation of effective prevention strategies. •To reduce the risk of and prevent sudden unexpected death in Parkinson's disease (SUDPAR) translational research and public campaigns are warranted.•Patients with Parkinson's disease should be regularly monitored for cardiac, pulmonary, and autonomic disorders. Classified as the second most common neurodegenerative disorder associated with aging after Alzheimer's disease, Parkinson's disease (PD) is the most common movement disorder. In the last decade, despite advances in treatment, mortality rates linked with PD continued to reach significant figures. Available studies have shown that compared with healthy controls, patients with PD are accompanied by high rates of premature death. This is usually caused by factors such as pneumonia and cerebrovascular and cardiovascular diseases. Recently, it has been demonstrated that a significant proportion of patients with PD die suddenly. This is referred to as a sudden and unexpected death in PD (SUDPAR). Here, we focus on the magnitude of SUDPAR. Finally, it is important to learn more about SUDPAR for the implementation of effective prevention strategies. Abstract Classified as the second most common neurodegenerative disorder associated with aging after Alzheimer's disease, Parkinson's disease (PD) is the most common movement disorder. In the last decade, despite advances in treatment, mortality rates linked with PD continued to reach significant figures. Available studies have shown that compared with healthy controls, patients with PD are accompanied by high rates of premature death. This is usually caused by factors such as pneumonia and cerebrovascular and cardiovascular diseases. Recently, it has been demonstrated that a significant proportion of patients with PD die suddenly. This is referred to as a sudden and unexpected death in PD (SUDPAR). Here, we focus on the magnitude of SUDPAR. Finally, it is important to learn more about SUDPAR for the implementation of effective prevention strategies. |
ArticleNumber | 100001 |
Author | Nejm, Mariana Finsterer, Josef Scorza, Fulvio A. Guimarães-Marques, Marcia Fiorini, Ana C. Scorza, Carla A. de Almeida, Antônio Carlos G. |
AuthorAffiliation | Messerli Institute Universidade Federal de São João del-Rei (UFSJ) Phonoaudiology Post graduation Program, Pontifícia Universidade Católica de São Paulo (PUC-SP) Universidade Federal de São Paulo (UNIFESP) |
AuthorAffiliation_xml | – name: Messerli Institute – name: Universidade Federal de São João del-Rei (UFSJ) – name: Phonoaudiology Post graduation Program, Pontifícia Universidade Católica de São Paulo (PUC-SP) – name: Universidade Federal de São Paulo (UNIFESP) |
Author_xml | – sequence: 1 givenname: Fulvio A. orcidid: 0000-0002-0694-8674 surname: Scorza fullname: Scorza, Fulvio A. email: scorza@unifesp.br organization: Neuroscience Discipline, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil – sequence: 2 givenname: Marcia orcidid: 0000-0001-5421-8417 surname: Guimarães-Marques fullname: Guimarães-Marques, Marcia organization: Neuroscience Discipline, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil – sequence: 3 givenname: Mariana orcidid: 0000-0001-7244-4768 surname: Nejm fullname: Nejm, Mariana organization: Neuroscience Discipline, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil – sequence: 4 givenname: Antônio Carlos G. orcidid: 0000-0003-4893-338X surname: de Almeida fullname: de Almeida, Antônio Carlos G. organization: Neuroscience Center of the Woman Health “Professor Geraldo Rodrigues de Lima”, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil – sequence: 5 givenname: Carla A. orcidid: 0000-0001-7810-4748 surname: Scorza fullname: Scorza, Carla A. organization: Neuroscience Discipline, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil – sequence: 6 givenname: Ana C. orcidid: 0000-0003-2989-2308 surname: Fiorini fullname: Fiorini, Ana C. organization: Neuroscience Center of the Woman Health “Professor Geraldo Rodrigues de Lima”, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil – sequence: 7 givenname: Josef orcidid: 0000-0003-2839-7305 surname: Finsterer fullname: Finsterer, Josef organization: Klinikum Landstrasse, Messerli Institute, Vienna, Austria |
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Keywords | Heart Prevention Parkinson's disease Sudden death |
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Snippet | •To reduce the risk of and prevent sudden unexpected death in Parkinson's disease (SUDPAR) translational research and public campaigns are warranted.•Patients... Classified as the second most common neurodegenerative disorder associated with aging after Alzheimer's disease, Parkinson's disease (PD) is the most common... • To reduce the risk of and prevent sudden unexpected death in Parkinson's disease (SUDPAR) translational research and public campaigns are warranted. •... Abstract Classified as the second most common neurodegenerative disorder associated with aging after Alzheimer's disease, Parkinson's disease (PD) is the most... |
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SubjectTerms | Death, Sudden - etiology Heart Humans MEDICINE, GENERAL & INTERNAL Parkinson Disease - complications Parkinson's disease Prevention Review Sudden death |
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Title | Sudden unexpected death in Parkinson's disease: Insights from clinical practice |
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