Integrating Molecular Biology and Bioinformatics Education

Combined awareness about the power and limitations of bioinformatics and molecular biology enables advanced research based on high-throughput data. Despite an increasing demand of scientists with a combined background in both fields, the education of dry and wet lab subjects are often still separate...

Full description

Saved in:
Bibliographic Details
Published inJournal of integrative bioinformatics Vol. 16; no. 3; pp. 398 - 404
Main Authors Pucker, Boas, Schilbert, Hanna Marie, Schumacher, Sina Franziska
Format Journal Article
LanguageEnglish
Published Germany De Gruyter 30.05.2019
Subjects
Online AccessGet full text
ISSN1613-4516
1613-4516
DOI10.1515/jib-2019-0005

Cover

Loading…
Abstract Combined awareness about the power and limitations of bioinformatics and molecular biology enables advanced research based on high-throughput data. Despite an increasing demand of scientists with a combined background in both fields, the education of dry and wet lab subjects are often still separated. This work describes an example of integrated education with a focus on genomics and transcriptomics. Participants learned computational and molecular biology methods in the same practical course. Peer-review was applied as a teaching method to foster cooperative learning of students with heterogeneous backgrounds. The positive evaluation results indicate that this approach was accepted by the participants and would likely be suitable for wider scale application.
AbstractList Combined awareness about the power and limitations of bioinformatics and molecular biology enables advanced research based on high-throughput data. Despite an increasing demand of scientists with a combined background in both fields, the education of dry and wet lab subjects are often still separated. This work describes an example of integrated education with a focus on genomics and transcriptomics. Participants learned computational and molecular biology methods in the same practical course. Peer-review was applied as a teaching method to foster cooperative learning of students with heterogeneous backgrounds. The positive evaluation results indicate that this approach was accepted by the participants and would likely be suitable for wider scale application.
Combined awareness about the power and limitations of bioinformatics and molecular biology enables advanced research based on high-throughput data. Despite an increasing demand of scientists with a combined background in both fields, the education of dry and wet lab subjects are often still separated. This work describes an example of integrated education with a focus on genomics and transcriptomics. Participants learned computational and molecular biology methods in the same practical course. Peer-review was applied as a teaching method to foster cooperative learning of students with heterogeneous backgrounds. The positive evaluation results indicate that this approach was accepted by the participants and would likely be suitable for wider scale application.Combined awareness about the power and limitations of bioinformatics and molecular biology enables advanced research based on high-throughput data. Despite an increasing demand of scientists with a combined background in both fields, the education of dry and wet lab subjects are often still separated. This work describes an example of integrated education with a focus on genomics and transcriptomics. Participants learned computational and molecular biology methods in the same practical course. Peer-review was applied as a teaching method to foster cooperative learning of students with heterogeneous backgrounds. The positive evaluation results indicate that this approach was accepted by the participants and would likely be suitable for wider scale application.
Author Schilbert, Hanna Marie
Schumacher, Sina Franziska
Pucker, Boas
Author_xml – sequence: 1
  givenname: Boas
  orcidid: 0000-0002-3321-7471
  surname: Pucker
  fullname: Pucker, Boas
  email: bpucker@cebitec.uni-bielefeld.de
  organization: Genetics and Genomics of Plants, CeBiTec and Faculty of Biology, Bielefeld University, Bielefeld, Germany
– sequence: 2
  givenname: Hanna Marie
  orcidid: 0000-0003-0474-7753
  surname: Schilbert
  fullname: Schilbert, Hanna Marie
  organization: Genetics and Genomics of Plants, CeBiTec and Faculty of Biology, Bielefeld University, Bielefeld, Germany
– sequence: 3
  givenname: Sina Franziska
  orcidid: 0000-0003-1471-1287
  surname: Schumacher
  fullname: Schumacher, Sina Franziska
  organization: Bielefeld University, Bielefeld, Germany
BackLink https://www.ncbi.nlm.nih.gov/pubmed/31145692$$D View this record in MEDLINE/PubMed
BookMark eNp1kc9vFCEUx4mpsXXt0avZo5dRfg7gwUSbqpvU9FLPhIE3IxsWKjOj2f9eptuatqkhhG_g877vhe9LdJRyAoReE_yOCCLeb0PXUEx0gzEWz9AJaQlruCDt0T19jE7HcVsJzLTSEr9Ax4wQLlpNT9CHTZpgKHYKaVh_zxHcHG1Zfw455mG_tskvOqQ-l12F3Lg-97OrKqdX6Hlv4wint-cK_fhyfnX2rbm4_Lo5-3TROIHp1Ajq2q7jjEstKQaPae-JokTxTnqpBViuWd_jzktlQXsALmUFNBacam3ZCm0Ovj7brbkuYWfL3mQbzM1FLoOxpY4WwSinCVeWeW6BC8WUZD0ny-4pFopUr48Hr-u524F3kKZi4wPThy8p_DRD_m1aqZWqg67Q21uDkn_NME5mF0YHMdoEeR4NpYwpwdq6VujN_V7_mtx9fgXYAXAlj2OB3rgw3XxtbR2iIdgsKZuasllSNkvKtap5VHVn_D9eHfg_Nk5QfE173ldhtnkuqQb3dB1pGfsLqCO6IA
CitedBy_id crossref_primary_10_1186_s13020_020_00339_5
crossref_primary_10_47499_revistaaccb_v1i33_231
crossref_primary_10_1007_s11192_023_04683_9
crossref_primary_10_1007_s12079_021_00612_8
crossref_primary_10_1088_1742_6596_1747_1_012001
crossref_primary_10_1186_s12874_021_01304_y
crossref_primary_10_3389_fsysb_2022_1046230
crossref_primary_10_1007_s11192_021_04182_9
crossref_primary_10_1002_bmb_21424
crossref_primary_10_1093_biomethods_bpad008
crossref_primary_10_1186_s43141_020_00043_9
crossref_primary_10_1080_10255842_2020_1813280
crossref_primary_10_1038_s41598_023_44246_9
crossref_primary_10_47499_revistaaccb_v1i32_218
crossref_primary_10_1515_jib_2023_0033
crossref_primary_10_1186_s13104_023_06386_z
crossref_primary_10_1371_journal_pone_0312754
crossref_primary_10_1080_00219266_2024_2386250
crossref_primary_10_1186_s12920_023_01627_3
Cites_doi 10.1093/bib/bbx100
10.1101/407627
10.3389/fmolb.2018.00062
10.1038/nj0478
10.1186/s13059-014-0550-8
10.1371/journal.pcbi.1003496
10.1371/journal.pcbi.1003897
10.1093/femsle/fny204
10.1371/journal.pcbi.0010052
10.1371/journal.pone.0164321
10.1126/science.1095480
10.1093/bib/bbt023
10.1093/bioinformatics/btu170
10.1371/journal.pbio.0030196
10.1101/gr.107524.110
10.4161/fly.19695
10.1093/bioinformatics/bts635
10.1016/S0022-2836(05)80360-2
10.1186/2047-217X-1-18
10.1093/nar/gkt418
10.1073/pnas.1607532113
10.1093/nar/gkq1019
10.1371/journal.pcbi.1003896
10.1093/nar/gkr1090
10.28945/3131
10.3835/plantgenome2012.05.0005
10.1093/bib/bbt043
10.1093/bioinformatics/btt656
10.1371/journal.pone.0094077
10.1371/journal.pcbi.1005772
ContentType Journal Article
Copyright 2019, Boas Pucker et al., published by Walter de Gruyter GmbH, Berlin/Boston 2019 Boas Pucker et al., published by Walter de Gruyter GmbH, Berlin/Boston
Copyright_xml – notice: 2019, Boas Pucker et al., published by Walter de Gruyter GmbH, Berlin/Boston 2019 Boas Pucker et al., published by Walter de Gruyter GmbH, Berlin/Boston
DBID AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7X8
5PM
DOA
DOI 10.1515/jib-2019-0005
DatabaseName CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
MEDLINE - Academic
PubMed Central (Full Participant titles)
DOAJ Directory of Open Access Journals
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
MEDLINE - Academic
DatabaseTitleList
MEDLINE - Academic


CrossRef
MEDLINE
Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Biology
EISSN 1613-4516
EndPage 404
ExternalDocumentID oai_doaj_org_article_8c9148a3d4ae4583873f413f41f20581
PMC6798849
31145692
10_1515_jib_2019_0005
10_1515_jib_2019_0005163
Genre Journal Article
GroupedDBID ---
2WC
53G
ABFKT
AFBDD
AHGSO
AIKXB
ALMA_UNASSIGNED_HOLDINGS
EMOBN
F-.
FRP
GROUPED_DOAJ
HYE
KQ8
OK1
PGMZT
QD8
RPM
W2D
AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7X8
5PM
ID FETCH-LOGICAL-c502t-52c6bb43479720ed02fd182184b7d795ea493ff0bd78ae9dee4771829054299a3
IEDL.DBID DOA
ISSN 1613-4516
IngestDate Wed Aug 27 01:25:59 EDT 2025
Thu Aug 21 14:13:23 EDT 2025
Thu Jul 10 18:31:56 EDT 2025
Thu Apr 03 07:11:04 EDT 2025
Tue Jul 01 02:56:55 EDT 2025
Thu Apr 24 22:57:50 EDT 2025
Sat Sep 06 17:01:44 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 3
Keywords molecular biology
RNA-Seq
bioinformatics
teaching
variant calling
NGS
transcriptome assembly
genome research
sequencing technologies
genome assembly
Language English
License This work is licensed under the Creative Commons Attribution 4.0 Public License.
http://creativecommons.org/licenses/by/4.0
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c502t-52c6bb43479720ed02fd182184b7d795ea493ff0bd78ae9dee4771829054299a3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ORCID 0000-0003-0474-7753
0000-0003-1471-1287
0000-0002-3321-7471
OpenAccessLink https://doaj.org/article/8c9148a3d4ae4583873f413f41f20581
PMID 31145692
PQID 2233853636
PQPubID 23479
PageCount 7
ParticipantIDs doaj_primary_oai_doaj_org_article_8c9148a3d4ae4583873f413f41f20581
pubmedcentral_primary_oai_pubmedcentral_nih_gov_6798849
proquest_miscellaneous_2233853636
pubmed_primary_31145692
crossref_citationtrail_10_1515_jib_2019_0005
crossref_primary_10_1515_jib_2019_0005
walterdegruyter_journals_10_1515_jib_2019_0005163
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2019-05-30
PublicationDateYYYYMMDD 2019-05-30
PublicationDate_xml – month: 05
  year: 2019
  text: 2019-05-30
  day: 30
PublicationDecade 2010
PublicationPlace Germany
PublicationPlace_xml – name: Germany
PublicationTitle Journal of integrative bioinformatics
PublicationTitleAlternate J Integr Bioinform
PublicationYear 2019
Publisher De Gruyter
Publisher_xml – name: De Gruyter
References Tennant, JP (j_jib-2019-0005_ref_032) 2018; 365
Pucker, B; Holtgräwe, D; Stadermann, KB; Frey, K; Huettel, B; Reinhardt, R; Weisshaar, B (j_jib-2019-0005_ref_031) 2018
Pucker, B; Holtgräwe, S; Rosleff Sörensen, T; Stracke, R; Viehöver, P; Weisshaar, B (j_jib-2019-0005_ref_011) 2016; 11
Bialek, W. (j_jib-2019-0005_ref_005) 2004; 303
Haak, M; Vinke, S; Keller, W; Droste, J; Rückert, C; Kalinowski, J; Pucker, B (j_jib-2019-0005_ref_026) 2018; 5
Welch, L; Lewitter, F; Schwartz, R; Brooksbank, C; Radivojac, P; Gaeta, B; Schneider, MV (j_jib-2019-0005_ref_003) 2014; 10
Rubinstein, A; Chor, B (j_jib-2019-0005_ref_007) 2014; 10
Hoff, KJ; Stanke, M (j_jib-2019-0005_ref_016) 2013; 41
Poland, JA; Rife, TW (j_jib-2019-0005_ref_018) 2012; 5
Dobin, A; Davis, CA; Schlesinger, F; Drenkow, J; Zaleski, C; Jha, S (j_jib-2019-0005_ref_023) 2013; 29
Liao, Y; Smyth, GK; Shi, W (j_jib-2019-0005_ref_024) 2014; 30
Zapata, L; Ding, J; Willing, E-M; Hartwig, B; Bezdan, D; Jiao, W-B (j_jib-2019-0005_ref_030) 2016; 113
Attwood, TK; Blackford, S; Brazas, MD; Davies, A; Schneider, MV (j_jib-2019-0005_ref_002) 2017; 20
Williams, KC; Williams, CC (j_jib-2019-0005_ref_033) 2011
Lamesch, P; Berardini, TZ; Li, D; Swarbreck, D; Wilks, C; Sasidharan, R (j_jib-2019-0005_ref_020) 2012; 40
McKenna, A; Hanna, M; Banks, E; Sivachenko, A; Cibulskis, K; Kernytsky, A (j_jib-2019-0005_ref_021) 2010; 20
Nordborg, M; Hu, TT; Ishino, Y; Jhaveri, J; Toomajian, C; Zheng, H (j_jib-2019-0005_ref_028) 2005; 3
Parker, K; Chao, J (j_jib-2019-0005_ref_034) 2007; 3
(j_jib-2019-0005_ref_001) 2016
Luo, R; Liu, B; Xie, Y; Li, Z; Huang, W; Yuan, J (j_jib-2019-0005_ref_015) 2012; 1
Li, H (j_jib-2019-0005_ref_019) 2013
Altschul, SF; Gish, W; Miller, W; Myers, EW; Lipman, DJ (j_jib-2019-0005_ref_017) 1990; 215
Ranganathan, S (j_jib-2019-0005_ref_004) 2005; 1
Leinonen, R; Sugawara, H; Shumway, M (j_jib-2019-0005_ref_012) 2011; 39
Vukašinović, N; Cvrčková, F; Eliáš, M; Cole, R; Fowler, JE; Žárský, V (j_jib-2019-0005_ref_029) 2014; 9
Bolger, AM; Lohse, M; Usadel, B (j_jib-2019-0005_ref_013) 2014; 30
Mulder, N; Schwartz, R; Brazas, MD; Brooksbank, C; Gaeta, B; Morgan, SL (j_jib-2019-0005_ref_010) 2018; 14
Abeln, S; Molenaar, D; Feenstra, KA; Hoefsloot, HCJ; Teusink, B; Heringa, J (j_jib-2019-0005_ref_006) 2013; 14
Goodman, AL; Dekhtyar, A (j_jib-2019-0005_ref_008) 2014; 10
Love, MI; Huber, W; Anders, S (j_jib-2019-0005_ref_025) 2014; 15
Cingolani, P; Platts, A; Wang, LL; Coon, M; Nguyen, T; Wang, L (j_jib-2019-0005_ref_022) 2012; 6
Via, A; Blicher, T; Bongcam-Rudloff, E; Brazas, MD; Brooksbank, C; Budd, A (j_jib-2019-0005_ref_009) 2013; 14
2023033120074885990_j_jib-2019-0005_ref_030_w2aab3b7b3b1b6b1ab1b5c30Aa
2023033120074885990_j_jib-2019-0005_ref_002_w2aab3b7b3b1b6b1ab1b5b2Aa
2023033120074885990_j_jib-2019-0005_ref_007_w2aab3b7b3b1b6b1ab1b5b7Aa
2023033120074885990_j_jib-2019-0005_ref_003_w2aab3b7b3b1b6b1ab1b5b3Aa
2023033120074885990_j_jib-2019-0005_ref_025_w2aab3b7b3b1b6b1ab1b5c25Aa
2023033120074885990_j_jib-2019-0005_ref_016_w2aab3b7b3b1b6b1ab1b5c16Aa
2023033120074885990_j_jib-2019-0005_ref_034_w2aab3b7b3b1b6b1ab1b5c34Aa
2023033120074885990_j_jib-2019-0005_ref_012_w2aab3b7b3b1b6b1ab1b5c12Aa
2023033120074885990_j_jib-2019-0005_ref_021_w2aab3b7b3b1b6b1ab1b5c21Aa
2023033120074885990_j_jib-2019-0005_ref_011_w2aab3b7b3b1b6b1ab1b5c11Aa
2023033120074885990_j_jib-2019-0005_ref_020_w2aab3b7b3b1b6b1ab1b5c20Aa
2023033120074885990_j_jib-2019-0005_ref_029_w2aab3b7b3b1b6b1ab1b5c29Aa
2023033120074885990_j_jib-2019-0005_ref_028_w2aab3b7b3b1b6b1ab1b5c28Aa
2023033120074885990_j_jib-2019-0005_ref_015_w2aab3b7b3b1b6b1ab1b5c15Aa
2023033120074885990_j_jib-2019-0005_ref_006_w2aab3b7b3b1b6b1ab1b5b6Aa
2023033120074885990_j_jib-2019-0005_ref_033_w2aab3b7b3b1b6b1ab1b5c33Aa
2023033120074885990_j_jib-2019-0005_ref_009_w2aab3b7b3b1b6b1ab1b5b9Aa
2023033120074885990_j_jib-2019-0005_ref_024_w2aab3b7b3b1b6b1ab1b5c24Aa
2023033120074885990_j_jib-2019-0005_ref_010_w2aab3b7b3b1b6b1ab1b5c10Aa
2023033120074885990_j_jib-2019-0005_ref_019_w2aab3b7b3b1b6b1ab1b5c19Aa
2023033120074885990_j_jib-2019-0005_ref_027_w2aab3b7b3b1b6b1ab1b5c27Aa
2023033120074885990_j_jib-2019-0005_ref_018_w2aab3b7b3b1b6b1ab1b5c18Aa
2023033120074885990_j_jib-2019-0005_ref_023_w2aab3b7b3b1b6b1ab1b5c23Aa
2023033120074885990_j_jib-2019-0005_ref_014_w2aab3b7b3b1b6b1ab1b5c14Aa
2023033120074885990_j_jib-2019-0005_ref_005_w2aab3b7b3b1b6b1ab1b5b5Aa
2023033120074885990_j_jib-2019-0005_ref_032_w2aab3b7b3b1b6b1ab1b5c32Aa
2023033120074885990_j_jib-2019-0005_ref_008_w2aab3b7b3b1b6b1ab1b5b8Aa
2023033120074885990_j_jib-2019-0005_ref_017_w2aab3b7b3b1b6b1ab1b5c17Aa
2023033120074885990_j_jib-2019-0005_ref_004_w2aab3b7b3b1b6b1ab1b5b4Aa
2023033120074885990_j_jib-2019-0005_ref_001_w2aab3b7b3b1b6b1ab1b5b1Aa
2023033120074885990_j_jib-2019-0005_ref_026_w2aab3b7b3b1b6b1ab1b5c26Aa
2023033120074885990_j_jib-2019-0005_ref_013_w2aab3b7b3b1b6b1ab1b5c13Aa
2023033120074885990_j_jib-2019-0005_ref_031_w2aab3b7b3b1b6b1ab1b5c31Aa
2023033120074885990_j_jib-2019-0005_ref_022_w2aab3b7b3b1b6b1ab1b5c22Aa
References_xml – volume: 113
  start-page: E4052
  year: 2016
  end-page: 60
  ident: j_jib-2019-0005_ref_030
  article-title: Chromosome-level assembly of Arabidopsis thaliana Ler reveals the extent of translocation and inversion polymorphisms
  publication-title: Proc Natl Acad Sci
– volume: 3
  start-page: e196
  year: 2005
  ident: j_jib-2019-0005_ref_028
  article-title: The pattern of polymorphism in Arabidopsis thaliana
  publication-title: PLoS Biol
– volume: 41
  start-page: W123
  year: 2013
  end-page: 8
  ident: j_jib-2019-0005_ref_016
  article-title: WebAUGUSTUS – a web service for training AUGUSTUS and predicting genes in eukaryotes
  publication-title: Nucleic Acids Res
– volume: 215
  start-page: 403
  year: 1990
  end-page: 10
  ident: j_jib-2019-0005_ref_017
  article-title: Basic local alignment search tool
  publication-title: J Mol Biol
– volume: 20
  start-page: 398
  issue: 2
  year: 2017
  end-page: 404
  ident: j_jib-2019-0005_ref_002
  article-title: A global perspective on evolving bioinformatics and data science training needs
  publication-title: Briefings in Bioinformatics
  doi: 10.1093/bib/bbx100
– year: 2013
  ident: j_jib-2019-0005_ref_019
  article-title: Aligning sequence reads, clone sequences and assembly contigs with BWA-MEM
  publication-title: ArXiv13033997 Q-Bio
– volume: 3
  start-page: 57
  year: 2007
  end-page: 72
  ident: j_jib-2019-0005_ref_034
  article-title: Wiki as a teaching tool
  publication-title: Interdiscip J E-Learn Learn Objects
– volume: 6
  start-page: 80
  year: 2012
  end-page: 92
  ident: j_jib-2019-0005_ref_022
  article-title: A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff
  publication-title: Fly (Austin)
– volume: 10
  start-page: e1003896
  year: 2014
  ident: j_jib-2019-0005_ref_008
  article-title: Teaching bioinformatics in concert
  publication-title: PLoS Comput Biol
– year: 2018
  ident: j_jib-2019-0005_ref_031
  article-title: A Chromosome-level Sequence Assembly Reveals the Structure of the Arabidopsis thaliana Nd-1 Genome and its Gene Set
  publication-title: bioRxiv
  doi: 10.1101/407627
– volume: 5
  year: 2018
  ident: j_jib-2019-0005_ref_026
  article-title: High Quality de Novo Transcriptome Assembly of Croton tiglium
  publication-title: Frontiers in Molecular Biosciences
  doi: 10.3389/fmolb.2018.00062
– volume: 14
  year: 2018
  ident: j_jib-2019-0005_ref_010
  article-title: The development and application of bioinformatics core competencies to improve bioinformatics training and education
  publication-title: PLoS Comput Biol
– year: 2016
  ident: j_jib-2019-0005_ref_001
  article-title: Spotlight on Bioinformatics
  publication-title: NatureJobs
  doi: 10.1038/nj0478
– volume: 30
  start-page: 923
  year: 2014
  end-page: 30
  ident: j_jib-2019-0005_ref_024
  article-title: featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
  publication-title: Bioinforma Oxf Engl
– volume: 15
  issue: 12
  year: 2014
  ident: j_jib-2019-0005_ref_025
  article-title: Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
  publication-title: Genome Biology
  doi: 10.1186/s13059-014-0550-8
– volume: 10
  start-page: e1003496
  issue: 3
  year: 2014
  end-page: e1003496
  ident: j_jib-2019-0005_ref_003
  article-title: Bioinformatics Curriculum Guidelines: Toward a Definition of Core Competencies
  publication-title: PLoS Computational Biology
  doi: 10.1371/journal.pcbi.1003496
– volume: 1
  start-page: 18
  year: 2012
  ident: j_jib-2019-0005_ref_015
  article-title: SOAPdenovo2: an empirically improved memory-efficient short-read de novo assembler
  publication-title: GigaScience
– volume: 10
  start-page: e1003897
  issue: 11
  year: 2014
  end-page: e1003897
  ident: j_jib-2019-0005_ref_007
  article-title: Computational Thinking in Life Science Education
  publication-title: PLoS Computational Biology
  doi: 10.1371/journal.pcbi.1003897
– volume: 365
  issue: 19
  year: 2018
  ident: j_jib-2019-0005_ref_032
  article-title: The state of the art in peer review
  publication-title: FEMS Microbiology Letters
  doi: 10.1093/femsle/fny204
– volume: 1
  start-page: e52
  issue: 6
  year: 2005
  end-page: e52
  ident: j_jib-2019-0005_ref_004
  article-title: Bioinformatics Education—Perspectives and Challenges
  publication-title: PLoS Computational Biology
  doi: 10.1371/journal.pcbi.0010052
– volume: 29
  start-page: 15
  year: 2013
  end-page: 21
  ident: j_jib-2019-0005_ref_023
  article-title: STAR: ultrafast universal RNA-seq aligner
  publication-title: Bioinformatics
– volume: 5
  start-page: 92
  year: 2012
  end-page: 102
  ident: j_jib-2019-0005_ref_018
  article-title: Genotyping-by-sequencing for plant breeding and genetics
  publication-title: Plant Genome
– start-page: 121
  year: 2011
  end-page: 3
  ident: j_jib-2019-0005_ref_033
  article-title: Five key ingredients for improving student motivation
  publication-title: Res High Educ J
– volume: 9
  year: 2014
  ident: j_jib-2019-0005_ref_029
  article-title: Dissecting a hidden gene duplication: the Arabidopsis thaliana SEC10 locus
  publication-title: PloS One
– volume: 11
  start-page: e0164321
  issue: 10
  year: 2016
  end-page: e0164321
  ident: j_jib-2019-0005_ref_011
  article-title: A De Novo Genome Sequence Assembly of the Arabidopsis thaliana Accession Niederzenz-1 Displays Presence/Absence Variation and Strong Synteny
  publication-title: PLOS ONEPLOS
  doi: 10.1371/journal.pone.0164321
– volume: 40
  start-page: D1202
  year: 2012
  end-page: 10
  ident: j_jib-2019-0005_ref_020
  article-title: The Arabidopsis Information Resource (TAIR): improved gene annotation and new tools
  publication-title: Nucleic Acids Res
– volume: 303
  start-page: 788
  issue: 5659
  year: 2004
  end-page: 790
  ident: j_jib-2019-0005_ref_005
  article-title: Introductory Science and Mathematics Education for 21st-Century Biologists
  publication-title: Science
  doi: 10.1126/science.1095480
– volume: 39
  start-page: D19
  year: 2011
  end-page: 21
  ident: j_jib-2019-0005_ref_012
  article-title: The sequence read archive
  publication-title: Nucleic Acids Res
– volume: 14
  start-page: 589
  issue: 5
  year: 2013
  end-page: 598
  ident: j_jib-2019-0005_ref_006
  article-title: Bioinformatics and Systems Biology: bridging the gap between heterogeneous student backgrounds
  publication-title: Briefings in Bioinformatics
  doi: 10.1093/bib/bbt023
– volume: 30
  start-page: 2114
  issue: 15
  year: 2014
  end-page: 2120
  ident: j_jib-2019-0005_ref_013
  article-title: Trimmomatic: a flexible trimmer for Illumina sequence data
  publication-title: Bioinformatics
  doi: 10.1093/bioinformatics/btu170
– volume: 14
  start-page: 528
  year: 2013
  end-page: 37
  ident: j_jib-2019-0005_ref_009
  article-title: Best practices in bioinformatics training for life scientists
  publication-title: Brief Bioinform
– volume: 20
  start-page: 1297
  year: 2010
  end-page: 303
  ident: j_jib-2019-0005_ref_021
  article-title: The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data
  publication-title: Genome Res
– ident: 2023033120074885990_j_jib-2019-0005_ref_028_w2aab3b7b3b1b6b1ab1b5c28Aa
  doi: 10.1371/journal.pbio.0030196
– ident: 2023033120074885990_j_jib-2019-0005_ref_019_w2aab3b7b3b1b6b1ab1b5c19Aa
– ident: 2023033120074885990_j_jib-2019-0005_ref_002_w2aab3b7b3b1b6b1ab1b5b2Aa
  doi: 10.1093/bib/bbx100
– ident: 2023033120074885990_j_jib-2019-0005_ref_006_w2aab3b7b3b1b6b1ab1b5b6Aa
  doi: 10.1093/bib/bbt023
– ident: 2023033120074885990_j_jib-2019-0005_ref_021_w2aab3b7b3b1b6b1ab1b5c21Aa
  doi: 10.1101/gr.107524.110
– ident: 2023033120074885990_j_jib-2019-0005_ref_014_w2aab3b7b3b1b6b1ab1b5c14Aa
– ident: 2023033120074885990_j_jib-2019-0005_ref_022_w2aab3b7b3b1b6b1ab1b5c22Aa
  doi: 10.4161/fly.19695
– ident: 2023033120074885990_j_jib-2019-0005_ref_023_w2aab3b7b3b1b6b1ab1b5c23Aa
  doi: 10.1093/bioinformatics/bts635
– ident: 2023033120074885990_j_jib-2019-0005_ref_017_w2aab3b7b3b1b6b1ab1b5c17Aa
  doi: 10.1016/S0022-2836(05)80360-2
– ident: 2023033120074885990_j_jib-2019-0005_ref_015_w2aab3b7b3b1b6b1ab1b5c15Aa
  doi: 10.1186/2047-217X-1-18
– ident: 2023033120074885990_j_jib-2019-0005_ref_016_w2aab3b7b3b1b6b1ab1b5c16Aa
  doi: 10.1093/nar/gkt418
– ident: 2023033120074885990_j_jib-2019-0005_ref_032_w2aab3b7b3b1b6b1ab1b5c32Aa
  doi: 10.1093/femsle/fny204
– ident: 2023033120074885990_j_jib-2019-0005_ref_025_w2aab3b7b3b1b6b1ab1b5c25Aa
  doi: 10.1186/s13059-014-0550-8
– ident: 2023033120074885990_j_jib-2019-0005_ref_030_w2aab3b7b3b1b6b1ab1b5c30Aa
  doi: 10.1073/pnas.1607532113
– ident: 2023033120074885990_j_jib-2019-0005_ref_012_w2aab3b7b3b1b6b1ab1b5c12Aa
  doi: 10.1093/nar/gkq1019
– ident: 2023033120074885990_j_jib-2019-0005_ref_005_w2aab3b7b3b1b6b1ab1b5b5Aa
  doi: 10.1126/science.1095480
– ident: 2023033120074885990_j_jib-2019-0005_ref_008_w2aab3b7b3b1b6b1ab1b5b8Aa
  doi: 10.1371/journal.pcbi.1003896
– ident: 2023033120074885990_j_jib-2019-0005_ref_020_w2aab3b7b3b1b6b1ab1b5c20Aa
  doi: 10.1093/nar/gkr1090
– ident: 2023033120074885990_j_jib-2019-0005_ref_031_w2aab3b7b3b1b6b1ab1b5c31Aa
  doi: 10.1101/407627
– ident: 2023033120074885990_j_jib-2019-0005_ref_034_w2aab3b7b3b1b6b1ab1b5c34Aa
  doi: 10.28945/3131
– ident: 2023033120074885990_j_jib-2019-0005_ref_001_w2aab3b7b3b1b6b1ab1b5b1Aa
  doi: 10.1038/nj0478
– ident: 2023033120074885990_j_jib-2019-0005_ref_004_w2aab3b7b3b1b6b1ab1b5b4Aa
  doi: 10.1371/journal.pcbi.0010052
– ident: 2023033120074885990_j_jib-2019-0005_ref_018_w2aab3b7b3b1b6b1ab1b5c18Aa
  doi: 10.3835/plantgenome2012.05.0005
– ident: 2023033120074885990_j_jib-2019-0005_ref_013_w2aab3b7b3b1b6b1ab1b5c13Aa
  doi: 10.1093/bioinformatics/btu170
– ident: 2023033120074885990_j_jib-2019-0005_ref_007_w2aab3b7b3b1b6b1ab1b5b7Aa
  doi: 10.1371/journal.pcbi.1003897
– ident: 2023033120074885990_j_jib-2019-0005_ref_009_w2aab3b7b3b1b6b1ab1b5b9Aa
  doi: 10.1093/bib/bbt043
– ident: 2023033120074885990_j_jib-2019-0005_ref_026_w2aab3b7b3b1b6b1ab1b5c26Aa
  doi: 10.3389/fmolb.2018.00062
– ident: 2023033120074885990_j_jib-2019-0005_ref_024_w2aab3b7b3b1b6b1ab1b5c24Aa
  doi: 10.1093/bioinformatics/btt656
– ident: 2023033120074885990_j_jib-2019-0005_ref_011_w2aab3b7b3b1b6b1ab1b5c11Aa
  doi: 10.1371/journal.pone.0164321
– ident: 2023033120074885990_j_jib-2019-0005_ref_003_w2aab3b7b3b1b6b1ab1b5b3Aa
  doi: 10.1371/journal.pcbi.1003496
– ident: 2023033120074885990_j_jib-2019-0005_ref_027_w2aab3b7b3b1b6b1ab1b5c27Aa
– ident: 2023033120074885990_j_jib-2019-0005_ref_029_w2aab3b7b3b1b6b1ab1b5c29Aa
  doi: 10.1371/journal.pone.0094077
– ident: 2023033120074885990_j_jib-2019-0005_ref_033_w2aab3b7b3b1b6b1ab1b5c33Aa
– ident: 2023033120074885990_j_jib-2019-0005_ref_010_w2aab3b7b3b1b6b1ab1b5c10Aa
  doi: 10.1371/journal.pcbi.1005772
SSID ssj0000398970
Score 2.235861
Snippet Combined awareness about the power and limitations of bioinformatics and molecular biology enables advanced research based on high-throughput data. Despite an...
SourceID doaj
pubmedcentral
proquest
pubmed
crossref
walterdegruyter
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 398
SubjectTerms bioinformatics
Computational Biology - education
Female
genome assembly
genome research
Humans
Male
molecular biology
Molecular Biology - education
NGS
Opinion Papers
RNA-Seq
sequencing technologies
teaching
transcriptome assembly
variant calling
Title Integrating Molecular Biology and Bioinformatics Education
URI https://www.degruyter.com/doi/10.1515/jib-2019-0005
https://www.ncbi.nlm.nih.gov/pubmed/31145692
https://www.proquest.com/docview/2233853636
https://pubmed.ncbi.nlm.nih.gov/PMC6798849
https://doaj.org/article/8c9148a3d4ae4583873f413f41f20581
Volume 16
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3fS-QwEB5EEXwRf9xp71QqHD5ZzCZt0_imoq6C58Mp-BaaJlGPox66i_jf30yaXXbVwxcfCqVJaTIzzXzDJN8A_LDK-coXLEO0W2a5K0WmisZkeYng1lfSq1C07-Jn2b_Oz2-Km4lSX7QnrKMH7gS3VzUKEXstbF67kOOTwuPCi5fnrAiHrjn6vIlgKqzBQlVKskiqiT577_e9QYugEzuMStVNOKHA1f8ewHy7T3LxOeSwrbt9HL4MRjnT4IpOlmAxYsj0oBv7Msy4dgXmu6qSL6uwfxYpINArpRej8rdpbE_r1tJ9ZEwlluZ0vMvjC1yfHF8d9bNYIiFrCsYHGEY2pTE5HQeVnDnLuLcYMWDYZqSVqnB1roT3zFhZ1U5Z53KJ3ogrRnWqVC2-wmz70Lp1SDm-QuRmpkeURA1HYMi4bQxxzvd60iWwO5KZbiJ_OJWx-KMpjkARaxSxJhFTQrtIYGfc_W9HnPG_joekgHEn4rsOD9AKdLQC_ZEVJLA9Up_G_4OSHnXrHoZPGuGPQEhSijKBtU6d40_hvBA_Kp6AnFL01FimW9r7u8DBTcmrKlcJ9F6ZhI5rwNP7s0X4--0zJvwdFjprLjLBNmB28Dh0mwiPBmYL5g76p78ut8If8Q-IPAuL
linkProvider Directory of Open Access Journals
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwEB7BVoheqvJseAYJcSJax07imFuLKFvolgOtxM2KY7starPVblao_56ZxBuxtFw4RIpiW7E9duYbz-QbgLdWOV_6nCWIdoskc4VIVF6bJCsQ3PpSetUl7ZseFZOT7MuPfBVNuAhhldadzpfXbc-QOrazekkHZQPXAGrg8c9zg_Kl_29wFY3P2suLu7BREPgfwcbu5PP3b8NBCxOqVJIFfs0bjdf0UUfbfxvWvBkyufWrc2cPff1DK-1vw1aAk_FuL_8HcMc1D-Fen2Dy-hF8OAhsEKig4ukqE24cyuOqsXQfyFOJsDkeAj4ew8n-p-OPkyRkS0jqnPEWLcq6MCajP0MlZ84y7i0aD2jBGWmlyl2VKeE9M1aWlVPWuUyiYuKKUcoqVYknMGpmjduBmGMT4jkzKbET1RwxIuO2NkQ_n6bSRfB-NWe6DlTilNHiQpNJgVOscYo1TTH5tvMI3g3Vr3oOjX9V3CMBDJWI-rp7MJuf6rCTdFkrNOEqYbPKdU5fKTxqYrw8Z3mZRvBmJT6NW4X8H1XjZsuFRiQkEJ0UoojgaS_O4VU4LoSSikcg1wS91pf1kub8rKPjJj9WmakI0r-WhA6fg8Xto0Uk_Ow_2ryG-5Pj6aE-PDj6-hw2-4WcJ4K9gFE7X7qXCJJa8ypsg98YCQ1D
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Nb9QwEB3BViAuFd8EKAQJcSJax07smFtbWLZACxJU6s2KY7sUoWy13RXqv-9M4o26tFw4RIoSW7Fn7Mwbj_0G4LXTPlShZBmiXZkVXopMl43NCongNlQq6C5p3_6BnB4Wn47Ko0un-GlbpfPH8-X5omdIHbtZs6SFsoFrAC3w-NeJRf3S-RscReNTF27ChpSIRUawsT39-P3rsM7ChK60YpFe80rdNXPUsfZfBzWv7pjc_NNFs4emXjJKk7uwGdFkut2r_x7c8O19uNXnlzx_AO_2IhkE2qd0f5UIN43v07p1dB-5U4mvOR32ezyEw8mHH7vTLCZLyJqS8QU6lI20tqCDoYoz7xgPDn0HdOCsckqXvi60CIFZp6raa-d9odAucc0oY5WuxSMYtbPWP4GUYxWiObM5kRM1HCEi466xxD6f58on8HYlM9NEJnFKaPHbkEeBIjYoYkMiptB2mcCbofhpT6Hxr4I7pIChEDFfdw9m82MTJ5KpGo0eXC1cUfsu5qtEQEOMV-CsrPIEXq3UZ3CmUPijbv1seWYQCAkEJ1LIBB736hw-hf1CJKl5AmpN0WttWX_Tnvzs2LgpjFUVOoH8ryFh4t_g7PreIhB--h91XsLtb-8n5svewedncKcfx2Um2HMYLeZLv4UQaWFfxFlwAV5PDGk
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Integrating+Molecular+Biology+and+Bioinformatics+Education&rft.jtitle=Journal+of+integrative+bioinformatics&rft.au=Pucker%2C+Boas&rft.au=Schilbert%2C+Hanna+Marie&rft.au=Schumacher%2C+Sina+Franziska&rft.date=2019-05-30&rft.pub=De+Gruyter&rft.eissn=1613-4516&rft.volume=16&rft.issue=3&rft_id=info:doi/10.1515%2Fjib-2019-0005&rft.externalDBID=n%2Fa&rft.externalDocID=10_1515_jib_2019_0005163
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1613-4516&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1613-4516&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1613-4516&client=summon