The influence of low temperature on the radiation sensitivity of enzymes

• Published in: The Journal of biological chemistry Vol. 257; no. 22; pp. 13297 - 13299
• Main Authors: Kempner, E S, Haigler, H T
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 25.11.1982; American Society for Biochemistry and Molecular Biology
• Subjects: Cold Temperature; Enzymes - radiation effects; Hyaluronoglucosaminidase - metabolism; Hyaluronoglucosaminidase - radiation effects; Kinetics; L-Lactate Dehydrogenase - metabolism; L-Lactate Dehydrogenase - radiation effects; Malate Dehydrogenase - metabolism; Muramidase - metabolism; Muramidase - radiation effects; Radiation Tolerance; Ribonucleases - metabolism; Ribonucleases - radiation effects; Trypsin - metabolism; Trypsin - radiation effects

When enzymes are exposed to ionizing radiation at low temperatures there is a progressive decrease in radiation sensitivity: considerably more enzymatic activity remains after the same dose of radiation at low temperature compared to room temperature. Detailed studies of five enzymes reveals the qua...