Characterisation of gp34, a GPI-anchored protein expressed by schizonts of Theileria parva and T. annulata

• Published in: Molecular and biochemical parasitology Vol. 172; no. 2; pp. 113 - 120
• Main Authors: Xue, Gondga, von Schubert, Conrad, Hermann, Pascal, Peyer, Martina, Maushagen, Regina, Schmuckli-Maurer, Jacqueline, Bütikofer, Peter, Langsley, Gordon, Dobbelaere, Dirk A.E.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.08.2010; Amsterdam: Elsevier; Elsevier/North-Holland Biomedical Press
• Subjects: Amino Acid Sequence; Animals; Apicomplexa; Chlorocebus aethiops; Computational Biology - methods; COS Cells; Cytokinesis; Gene Expression; Glycosylphosphatidylinositol; GPI; HeLa Cells; Host-Parasite Interactions; Humans; Intracellular parasite; Membrane Proteins - genetics; Membrane Proteins - isolation & purification; Mitosis; Molecular Sequence Data; PBD; Plk1; Polo-like kinase1; polobox domain; Protein Sorting Signals; Protozoan Proteins - genetics; Protozoan Proteins - isolation & purification; Schizonts - metabolism; Sequence Alignment; Surface protein; Theileria annulata - genetics; Theileria annulata - metabolism; Theileria parva - genetics; Theileria parva - metabolism; Transformation; GPI; Apicomplexa; Transformation; PBD; Plk1; Mitosis; Intracellular parasite; Surface protein; Cytokinesis

We characterised gp34 (yellow), a GPI-anchored protein that is expressed on the surface of the schizont (red) of the transforming intracellular parasite Theileria. The host cell nucleus is stained blue. Using bioinformatics tools, we searched the predicted Theileria annulata and T. parva proteomes f...