Detection of Norovirus in Saliva Samples from Acute Gastroenteritis Cases and Asymptomatic Subjects: Association with Age and Higher Shedding in Stool

• Published in: Viruses Vol. 12; no. 12; p. 1369
• Main Authors: Anfruns-Estrada, Eduard, Sabrià, Aurora, Fuentes, Cristina, Sabaté, Sara, Razquin, Efrén, Cornejo, Thais, Bartolomé, Rosa, Torner, Nuria, Izquierdo, Conchita, Soldevila, Nuria, Coronas, Lorena, Dominguez, Angela, Pintó, Rosa, Bosch, Albert, Guix, Susana
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 30.11.2020; MDPI
• Subjects: Acute Disease; acute gastroenteritis; Asymptomatic; Asymptomatic Diseases; asymptomatic infection; Caliciviridae Infections - diagnosis; Caliciviridae Infections - epidemiology; Caliciviridae Infections - virology; Disease Outbreaks; Epidemics; Epidemiology; feces; Feces - virology; Female; FUT2 genotyping; Gastroenteritis; Gastroenteritis - diagnosis; Gastroenteritis - epidemiology; Gastroenteritis - virology; genome; Genomes; Genotype; human norovirus; Humans; Infections; Laboratories; Male; Norovirus; Norovirus - genetics; Norovirus - isolation & purification; Outbreaks; PMAxx-viability RTqPCR; propidium; RNA, Viral; Saliva; Saliva - virology; Sequence Analysis, DNA; Spain; Viral Load; Virus Shedding; Viruses; Spain; asymptomatic infection; saliva; FUT2 genotyping; human norovirus; acute gastroenteritis; PMAxx-viability RTqPCR

Norovirus infections are a leading cause of acute gastroenteritis outbreaks worldwide and across all age groups, with two main genogroups (GI and GII) infecting humans. The aim of our study was to investigate the occurrence of norovirus in saliva samples from individuals involved in outbreaks of acu...