Enhanced Mitogenic Signaling in Skeletal Muscle of Women With Polycystic Ovary Syndrome

• Published in: Diabetes (New York, N.Y.) Vol. 55; no. 3; pp. 751 - 759
• Main Authors: Corbould, Anne, Zhao, Haiyan, Mirzoeva, Salida, Aird, Fraser, Dunaif, Andrea
• Format: Journal Article
• Language: English
• Published: Alexandria, VA American Diabetes Association 01.03.2006
• Subjects: Adult; Androgens; Biological and medical sciences; Butadienes - pharmacology; Cell culture; Cells, Cultured; Defects; Diabetes; Diabetes research; Diabetes. Impaired glucose tolerance; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Extracellular Signal-Regulated MAP Kinases - metabolism; Female; Female genital diseases; Fibroblasts; Fundamental and applied biological sciences. Psychology; Glucose; Gynecology. Andrology. Obstetrics; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; Kinases; MAP Kinase Signaling System - physiology; Medical sciences; Metabolism; Muscle, Skeletal - metabolism; Musculoskeletal system; Nitriles - pharmacology; Non tumoral diseases; Ovaries; p38 Mitogen-Activated Protein Kinases - metabolism; Pathogenesis; Phosphoproteins - physiology; Phosphorylation; Polycystic ovary syndrome; Polycystic Ovary Syndrome - metabolism; Proteins; Proto-Oncogene Proteins c-raf - physiology; Proto-Oncogene Proteins p21(ras) - physiology; Risk factors; Stein-Leventhal syndrome; Striated muscle. Tendons; Type 2 diabetes; Vertebrates: osteoarticular system, musculoskeletal system; Endocrinopathy; Human; Ovarian diseases; Signal transduction; Diabetes mellitus; Cyst; Female sterility; Female; Benign neoplasm; Polycystic ovary; Striated muscle; Female genital diseases

Enhanced Mitogenic Signaling in Skeletal Muscle of Women With Polycystic Ovary Syndrome Anne Corbould 1 2 , Haiyan Zhao 1 , Salida Mirzoeva 1 , Fraser Aird 1 and Andrea Dunaif 1 2 1 Division of Endocrinology, Metabolism and Molecular Medicine, Feinberg School of Medicine, Northwestern University, Ch...