Pepper Mottle Virus and Its Host Interactions: Current State of Knowledge

Pepper mottle virus (PepMoV) is a destructive pathogen that infects various solanaceous plants, including pepper, bell pepper, potato, and tomato. In this review, we summarize what is known about the molecular characteristics of PepMoV and its interactions with host plants. Comparisons of symptom va...

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Published inViruses Vol. 13; no. 10; p. 1930
Main Authors Fang, Miao, Yu, Jisuk, Kim, Kook-Hyung
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 25.09.2021
MDPI
Subjects
Cloning
E coli
Genes, vpr
Genetic analysis
Genetic diversity
genetic variation
Genomes
Host Microbial Interactions - genetics
Host plants
Infections
Lycopersicon esculentum - genetics
Lycopersicon esculentum - virology
Molecular modelling
Pathogens
pepper
Pepper mottle virus
pepper resistance gene
Plant Diseases - genetics
Plant Diseases - virology
Plasmids
potatoes
Potyvirus
Potyvirus - genetics
Potyvirus - physiology
Proteins
reverse genetics
Review
Roles
Solanum tuberosum - genetics
Solanum tuberosum - virology
sweet peppers
tomatoes
transcriptomics
Viral infections
Viruses
virus–host interaction
North America
India
pepper mottle virus
virus–host interaction
Potyvirus
pepper resistance gene
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Abstract Pepper mottle virus (PepMoV) is a destructive pathogen that infects various solanaceous plants, including pepper, bell pepper, potato, and tomato. In this review, we summarize what is known about the molecular characteristics of PepMoV and its interactions with host plants. Comparisons of symptom variations caused by PepMoV isolates in plant hosts indicates a possible relationship between symptom development and genetic variation. Researchers have investigated the PepMoV–plant pathosystem to identify effective and durable genes that confer resistance to the pathogen. As a result, several recessive pvr or dominant Pvr resistance genes that confer resistance to PepMoV in pepper have been characterized. On the other hand, the molecular mechanisms underlying the interaction between these resistance genes and PepMoV-encoded genes remain largely unknown. Our understanding of the molecular interactions between PepMoV and host plants should be increased by reverse genetic approaches and comprehensive transcriptomic analyses of both the virus and the host genes.
AbstractList Pepper mottle virus (PepMoV) is a destructive pathogen that infects various solanaceous plants, including pepper, bell pepper, potato, and tomato. In this review, we summarize what is known about the molecular characteristics of PepMoV and its interactions with host plants. Comparisons of symptom variations caused by PepMoV isolates in plant hosts indicates a possible relationship between symptom development and genetic variation. Researchers have investigated the PepMoV-plant pathosystem to identify effective and durable genes that confer resistance to the pathogen. As a result, several recessive pvr or dominant Pvr resistance genes that confer resistance to PepMoV in pepper have been characterized. On the other hand, the molecular mechanisms underlying the interaction between these resistance genes and PepMoV-encoded genes remain largely unknown. Our understanding of the molecular interactions between PepMoV and host plants should be increased by reverse genetic approaches and comprehensive transcriptomic analyses of both the virus and the host genes.Pepper mottle virus (PepMoV) is a destructive pathogen that infects various solanaceous plants, including pepper, bell pepper, potato, and tomato. In this review, we summarize what is known about the molecular characteristics of PepMoV and its interactions with host plants. Comparisons of symptom variations caused by PepMoV isolates in plant hosts indicates a possible relationship between symptom development and genetic variation. Researchers have investigated the PepMoV-plant pathosystem to identify effective and durable genes that confer resistance to the pathogen. As a result, several recessive pvr or dominant Pvr resistance genes that confer resistance to PepMoV in pepper have been characterized. On the other hand, the molecular mechanisms underlying the interaction between these resistance genes and PepMoV-encoded genes remain largely unknown. Our understanding of the molecular interactions between PepMoV and host plants should be increased by reverse genetic approaches and comprehensive transcriptomic analyses of both the virus and the host genes.
(PepMoV) is a destructive pathogen that infects various solanaceous plants, including pepper, bell pepper, potato, and tomato. In this review, we summarize what is known about the molecular characteristics of PepMoV and its interactions with host plants. Comparisons of symptom variations caused by PepMoV isolates in plant hosts indicates a possible relationship between symptom development and genetic variation. Researchers have investigated the PepMoV-plant pathosystem to identify effective and durable genes that confer resistance to the pathogen. As a result, several recessive or dominant resistance genes that confer resistance to PepMoV in pepper have been characterized. On the other hand, the molecular mechanisms underlying the interaction between these resistance genes and PepMoV-encoded genes remain largely unknown. Our understanding of the molecular interactions between PepMoV and host plants should be increased by reverse genetic approaches and comprehensive transcriptomic analyses of both the virus and the host genes.
Pepper mottle virus (PepMoV) is a destructive pathogen that infects various solanaceous plants, including pepper, bell pepper, potato, and tomato. In this review, we summarize what is known about the molecular characteristics of PepMoV and its interactions with host plants. Comparisons of symptom variations caused by PepMoV isolates in plant hosts indicates a possible relationship between symptom development and genetic variation. Researchers have investigated the PepMoV–plant pathosystem to identify effective and durable genes that confer resistance to the pathogen. As a result, several recessive pvr or dominant Pvr resistance genes that confer resistance to PepMoV in pepper have been characterized. On the other hand, the molecular mechanisms underlying the interaction between these resistance genes and PepMoV-encoded genes remain largely unknown. Our understanding of the molecular interactions between PepMoV and host plants should be increased by reverse genetic approaches and comprehensive transcriptomic analyses of both the virus and the host genes.
Pepper mottle virus (PepMoV) is a destructive pathogen that infects various solanaceous plants, including pepper, bell pepper, potato, and tomato. In this review, we summarize what is known about the molecular characteristics of PepMoV and its interactions with host plants. Comparisons of symptom variations caused by PepMoV isolates in plant hosts indicates a possible relationship between symptom development and genetic variation. Researchers have investigated the PepMoV–plant pathosystem to identify effective and durable genes that confer resistance to the pathogen. As a result, several recessive pvr or dominant Pvr resistance genes that confer resistance to PepMoV in pepper have been characterized. On the other hand, the molecular mechanisms underlying the interaction between these resistance genes and PepMoV-encoded genes remain largely unknown. Our understanding of the molecular interactions between PepMoV and host plants should be increased by reverse genetic approaches and comprehensive transcriptomic analyses of both the virus and the host genes.
Author Fang, Miao
Kim, Kook-Hyung
Yu, Jisuk
AuthorAffiliation 2 Plant Genomics and Breeding Institute, Seoul National University, Seoul 08826, Korea; mago03@snu.ac.kr
1 Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, Korea; fmmy0506@gmail.com
3 Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Korea
AuthorAffiliation_xml – name: 2 Plant Genomics and Breeding Institute, Seoul National University, Seoul 08826, Korea; mago03@snu.ac.kr
– name: 3 Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Korea
– name: 1 Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, Korea; fmmy0506@gmail.com
Author_xml – sequence: 1
  givenname: Miao
  surname: Fang
  fullname: Fang, Miao
– sequence: 2
  givenname: Jisuk
  surname: Yu
  fullname: Yu, Jisuk
– sequence: 3
  givenname: Kook-Hyung
  orcidid: 0000-0001-9066-6903
  surname: Kim
  fullname: Kim, Kook-Hyung
BackLink https://www.ncbi.nlm.nih.gov/pubmed/34696360$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1128/jvi.68.4.2388-2397.1994
10.1111/tpj.13136
10.1128/JVI.01329-08
10.1007/s42161-018-00235-w
10.1016/S0168-1702(00)00161-1
10.1128/JVI.00024-16
10.3390/v12020132
10.1111/nph.13823
10.1016/S0042-6822(03)00387-8
10.1094/MPMI.2004.17.5.502
10.1111/j.1365-313X.2004.02233.x
10.1016/j.virol.2009.11.015
10.1128/JVI.75.14.6329-6336.2001
10.1128/JVI.00662-12
10.1016/bs.aivir.2014.11.006
10.1111/mpp.13017
10.1094/PDIS.2002.86.6.603
10.1099/jgv.0.000740
10.5197/j.2044-0588.2014.030.014
10.1111/j.1365-3059.2008.01992.x
10.1094/Phyto-85-561
10.3390/v7122935
10.1007/s00122-016-2723-1
10.1073/pnas.0800468105
10.1046/j.0960-7412.2000.00942.x
10.1094/PHYTO-07-17-0231-R
10.1186/s13765-020-00581-3
10.1016/j.tim.2019.05.007
10.1016/j.virusres.2010.02.004
10.3390/v11121158
10.1094/MPMI.2000.13.11.1266
10.1006/jsbi.1997.3856
10.1371/journal.ppat.1003985
10.1371/journal.pone.0119639
10.1016/0042-6822(92)90162-I
10.1101/gr.159402
10.1007/s00122-005-0120-2
10.1007/978-3-7091-6920-9_34
10.1093/jxb/err200
10.3390/v12020217
10.1007/s00705-002-0884-5
10.1094/PDIS-10-10-0721
10.1016/j.biochi.2006.02.012
10.1371/journal.ppat.1000962
10.1007/s40626-019-00143-z
10.1046/j.1365-313x.2000.00834.x
10.3389/fmicb.2020.00102
10.1007/s11032-009-9323-6
10.1016/j.tplants.2005.11.004
10.1094/PDIS.2002.86.2.186C
10.1094/MPMI-11-13-0333-CR
10.1016/j.gene.2018.05.004
10.1128/JVI.00913-07
10.1094/PHYTO-96-0240
10.1016/j.virol.2016.05.011
10.1104/pp.15.00332
10.1111/j.1364-3703.2009.00603.x
10.1111/nph.14177
10.1111/mpp.12341
10.1111/mpp.12973
10.1023/A:1003009721989
10.1002/j.1460-2075.1994.tb06403.x
10.1094/MPMI.1998.11.10.943
10.1099/0022-1317-80-10-2785
10.1073/pnas.89.21.10208
10.1094/MPMI-04-14-0111-R
10.1099/0022-1317-77-7-1335
10.1146/annurev.phyto.43.011205.141140
10.1007/s007050170187
10.1094/MPMI.2003.16.9.777
10.1111/j.1467-7652.2007.00262.x
10.1099/vir.0.035881-0
10.1007/s10327-003-0059-6
10.1146/annurev-phyto-020620-114550
10.1111/j.1365-313X.2005.02381.x
10.5423/PPJ.2008.24.2.152
10.1186/s12985-015-0369-2
10.1073/pnas.1904752116
10.1105/tpc.113.111658
10.1126/sciadv.aaw3808
10.1007/s00239-013-9601-0
10.3390/v13040688
10.1007/s00705-002-0915-2
10.1016/j.coviro.2011.09.010
10.1094/Phyto-65-559
10.1099/vir.0.81817-0
10.1128/JVI.01478-16
10.1016/j.jviromet.2014.02.003
10.5423/PPJ.2006.22.2.155
10.1016/S0168-1702(01)00220-9
10.1038/sdata.2018.103
10.1094/MPMI-19-1207
10.1093/gbe/evz069
10.3389/fpls.2020.01098
10.1073/pnas.93.22.12400
10.1094/MPMI-11-09-0277
10.1128/jvi.69.6.3668-3674.1995
10.3390/v12010077
10.1099/0022-1317-79-12-3119
10.1074/jbc.M703356200
10.1016/j.jviromet.2018.12.012
10.1046/j.1365-313X.1998.00120.x
10.1016/bs.aivir.2020.09.001
10.1006/viro.1995.1023
10.1016/j.biochi.2008.03.013
10.1016/j.virusres.2009.04.003
10.1002/9780470015902.a0000755.pub3
10.1094/Phyto-65-110
10.1016/j.virol.2007.12.014
10.1038/ncomms14493
10.1186/s12864-015-1666-2
10.1016/j.virol.2015.02.052
10.3389/fpls.2018.00666
10.1094/MPMI-02-12-0046-R
10.1007/s00705-017-3539-2
10.1111/j.1364-3703.2008.00513.x
10.1016/j.virusres.2010.12.004
10.1128/JVI.00052-11
10.1007/s00438-005-0003-x
10.5423/PPJ.2009.25.4.417
10.1111/mpp.12024
10.1128/JVI.00503-15
10.1128/JVI.02915-14
10.1094/PDIS-02-12-0147-PDN
10.1128/JVI.00485-11
10.1111/j.1364-3703.2012.00791.x
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Keywords pepper mottle virus
virus–host interaction
Potyvirus
pepper resistance gene
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References Li (ref_101) 2019; 27
Quenouille (ref_46) 2013; 14
Robaglia (ref_106) 2006; 11
Mandadi (ref_100) 2013; 25
ref_97
Kim (ref_130) 2018; 5
Dufresne (ref_82) 2008; 374
Kang (ref_115) 2005; 42
Fares (ref_52) 2014; 78
Carrington (ref_71) 1994; 68
ref_18
Song (ref_24) 2017; 162
Zitter (ref_11) 1975; 65
Zhang (ref_30) 2019; 101
Blanc (ref_53) 1998; 79
Constantin (ref_42) 2004; 40
Guiraud (ref_64) 2009; 10
Doublet (ref_63) 2012; 93
ref_126
Venkatesh (ref_119) 2018; 108
Varjosalo (ref_72) 2016; 17
ref_25
Cheng (ref_83) 2017; 91
ref_20
Seo (ref_98) 2010; 11
Verchot (ref_48) 1995; 69
Satyanarayana (ref_35) 2003; 313
Sorel (ref_61) 2014; 27
Jiang (ref_67) 2015; 89
Dolja (ref_95) 1994; 13
Eskelin (ref_75) 2011; 85
Kang (ref_81) 2005; 43
Goytia (ref_55) 2011; 85
Chung (ref_32) 2008; 105
Guerini (ref_109) 1999; 80
Nakahara (ref_49) 2010; 23
Grzela (ref_78) 2006; 88
Yoon (ref_127) 2021; 64
Sorel (ref_65) 2014; 27
Llave (ref_99) 2002; 147
(ref_40) 2000; 68
Jin (ref_54) 2007; 81
Spetz (ref_66) 2004; 17
Zitter (ref_2) 1972; 56
Mestre (ref_85) 2000; 23
Yeam (ref_111) 2005; 112
Dolja (ref_91) 1995; 206
(ref_90) 2020; 108
Miyoshi (ref_79) 2008; 90
Tran (ref_21) 2015; 481
Creamer (ref_5) 2002; 86
Jonson (ref_19) 2009; 25
Revers (ref_31) 2015; 92
Dai (ref_93) 2020; 21
Tuo (ref_41) 2015; 7
Wang (ref_80) 2012; 13
Whitham (ref_123) 2006; 19
Lee (ref_29) 2011; 155
Yoon (ref_22) 2020; 11
Janzac (ref_105) 2009; 58
Kyle (ref_107) 1997; 97
Ivanov (ref_92) 2015; 89
Cui (ref_57) 2010; 397
Kim (ref_120) 2017; 213
Yang (ref_47) 2021; 59
Haenni (ref_34) 2001; 74
Murphy (ref_104) 1998; 11
Ruffel (ref_112) 2005; 274
Olsen (ref_39) 2001; 146
Goritschnig (ref_122) 2016; 210
Murphy (ref_14) 2006; 96
Lerich (ref_73) 2011; 62
ref_50
Zhu (ref_129) 2018; 666
Kang (ref_113) 2007; 5
Gauffier (ref_114) 2016; 85
Jiang (ref_74) 2011; 1
Zanardo (ref_128) 2019; 31
Johansen (ref_38) 1996; 93
ref_58
Deng (ref_44) 2015; 12
Collmer (ref_117) 2000; 13
Tangjang (ref_10) 2018; 115
Zhang (ref_118) 2012; 25
Tran (ref_102) 2014; 201
Vance (ref_17) 1992; 191
Jenner (ref_59) 2003; 16
Han (ref_12) 2006; 22
Carrington (ref_62) 1998; 14
Ogawa (ref_3) 2003; 69
Purcifull (ref_27) 1975; 65
Kaur (ref_9) 2014; 30
Meyers (ref_121) 2002; 12
Maia (ref_51) 1996; 77
Ratcliff (ref_43) 2001; 25
Dolja (ref_45) 1992; 89
Pavan (ref_108) 2010; 25
ref_69
Cheng (ref_8) 2011; 95
Goyer (ref_124) 2015; 16
Butterbach (ref_116) 2014; 5
Tran (ref_23) 2019; 265
Wei (ref_70) 2008; 82
Melzer (ref_7) 2012; 96
Casteel (ref_86) 2015; 169
Hiebert (ref_28) 1992; 5
Langenberg (ref_56) 1997; 118
Bak (ref_87) 2017; 8
Kim (ref_13) 2008; 24
Khan (ref_77) 2008; 283
Yan (ref_96) 2021; 22
Gao (ref_37) 2012; 86
Gong (ref_88) 2020; 11
Kim (ref_4) 2009; 144
Tran (ref_125) 2016; 495
Verhoeven (ref_6) 2002; 86
Wu (ref_68) 2019; 11
ref_1
Warren (ref_16) 2003; 148
Arazi (ref_94) 2001; 75
Murphy (ref_15) 1995; 85
Cui (ref_60) 2016; 90
Rodamilans (ref_84) 2018; 9
Ruffel (ref_110) 2006; 87
Volpon (ref_76) 2019; 116
Coll (ref_89) 2019; 5
(ref_33) 2014; 5
Wylie (ref_26) 2017; 98
Bedoya (ref_36) 2010; 149
Liu (ref_103) 2016; 129
References_xml – volume: 68
  start-page: 2388
  year: 1994
  ident: ref_71
  article-title: The tobacco etch potyvirus 6-kilodalton protein is membrane associated and involved in viral replication
  publication-title: J. Virol.
  doi: 10.1128/jvi.68.4.2388-2397.1994
– volume: 85
  start-page: 717
  year: 2016
  ident: ref_114
  article-title: A TILLING approach to generate broad-spectrum resistance to potyviruses in tomato is hampered by eIF4E gene redundancy
  publication-title: Plant J.
  doi: 10.1111/tpj.13136
– volume: 82
  start-page: 12252
  year: 2008
  ident: ref_70
  article-title: Biogenesis of cytoplasmic membranous vesicles for plant potyvirus replication occurs at endoplasmic reticulum exit sites in a COPI-and COPII-dependent manner
  publication-title: J. Virol.
  doi: 10.1128/JVI.01329-08
– volume: 101
  start-page: 559
  year: 2019
  ident: ref_30
  article-title: Genome and phylogenetic analyses of chinese pepper mottle virus isolates from chili pepper plants
  publication-title: J. Plant Pathol.
  doi: 10.1007/s42161-018-00235-w
– volume: 68
  start-page: 99
  year: 2000
  ident: ref_40
  article-title: Construction of a stable and highly infectious intron-containing cDNA clone of plum pox potyvirus and its use to infect plants by particle bombardment
  publication-title: Virus Res.
  doi: 10.1016/S0168-1702(00)00161-1
– volume: 90
  start-page: 5119
  year: 2016
  ident: ref_60
  article-title: Plum pox virus 6K1 protein is required for viral replication and targets the viral replication complex at the early stage of infection
  publication-title: J. Virol.
  doi: 10.1128/JVI.00024-16
– ident: ref_25
  doi: 10.3390/v12020132
– volume: 210
  start-page: 984
  year: 2016
  ident: ref_122
  article-title: Structurally distinct Arabidopsis thaliana NLR immune receptors recognize tandem WY domains of an oomycete effector
  publication-title: New Phytol.
  doi: 10.1111/nph.13823
– volume: 313
  start-page: 481
  year: 2003
  ident: ref_35
  article-title: Frameshift mutations in infectious cDNA clones of citrus tristeza virus: A strategy to minimize the toxicity of viral sequences to Escherichia coli
  publication-title: Virology
  doi: 10.1016/S0042-6822(03)00387-8
– volume: 17
  start-page: 502
  year: 2004
  ident: ref_66
  article-title: Potyviral 6K2 protein long-distance movement and symptom-induction functions are independent and host-specific
  publication-title: Mol. Plant-Microbe Interact.
  doi: 10.1094/MPMI.2004.17.5.502
– volume: 40
  start-page: 622
  year: 2004
  ident: ref_42
  article-title: Virus-induced gene silencing as a tool for functional genomics in a legume species
  publication-title: Plant J.
  doi: 10.1111/j.1365-313X.2004.02233.x
– volume: 397
  start-page: 56
  year: 2010
  ident: ref_57
  article-title: The tobacco etch virus P3 protein forms mobile inclusions via the early secretory pathway and traffics along actin microfilaments
  publication-title: Virology
  doi: 10.1016/j.virol.2009.11.015
– volume: 75
  start-page: 6329
  year: 2001
  ident: ref_94
  article-title: A nonviral peptide can replace the entire N terminus of zucchini yellow mosaic potyvirus coat protein and permits viral systemic infection
  publication-title: J. Virol.
  doi: 10.1128/JVI.75.14.6329-6336.2001
– volume: 86
  start-page: 7043
  year: 2012
  ident: ref_37
  article-title: The influenza A virus PB2, PA, NP, and M segments play a pivotal role during genome packaging
  publication-title: J. Virol.
  doi: 10.1128/JVI.00662-12
– volume: 92
  start-page: 101
  year: 2015
  ident: ref_31
  article-title: Molecular biology of potyviruses
  publication-title: Adv. Virus Res.
  doi: 10.1016/bs.aivir.2014.11.006
– volume: 22
  start-page: 189
  year: 2021
  ident: ref_96
  article-title: The conserved aromatic residue W122 is a determinant of potyviral coat protein stability, replication, and cell-to-cell movement in plants
  publication-title: Mol. Plant Pathol.
  doi: 10.1111/mpp.13017
– volume: 86
  start-page: 603
  year: 2002
  ident: ref_5
  article-title: Pepper mottle virus causing disease in chile peppers in southern New Mexico
  publication-title: Plant Dis.
  doi: 10.1094/PDIS.2002.86.6.603
– volume: 98
  start-page: 352
  year: 2017
  ident: ref_26
  article-title: ICTV virus taxonomy profile: Potyviridae
  publication-title: J. Gen. Virol.
  doi: 10.1099/jgv.0.000740
– volume: 30
  start-page: 14
  year: 2014
  ident: ref_9
  article-title: First report of pepper mottle virus infecting chilli pepper in India
  publication-title: New Dis. Rep.
  doi: 10.5197/j.2044-0588.2014.030.014
– volume: 58
  start-page: 443
  year: 2009
  ident: ref_105
  article-title: Phenotype and spectrum of action of the Pvr4 resistance in pepper against potyviruses, and selection for virulent variants
  publication-title: Plant Pathol.
  doi: 10.1111/j.1365-3059.2008.01992.x
– volume: 85
  start-page: 561
  year: 1995
  ident: ref_15
  article-title: Alleviation of restricted systemic spread of pepper mottle potyvirus in Capsicum annuum cv. Avelar by coinfection with a cucumovirus
  publication-title: Phytopathology
  doi: 10.1094/Phyto-85-561
– volume: 7
  start-page: 6241
  year: 2015
  ident: ref_41
  article-title: Rapid construction of stable infectious full-length cDNA clone of papaya leaf distortion mosaic virus using in-fusion cloning
  publication-title: Viruses
  doi: 10.3390/v7122935
– volume: 129
  start-page: 1541
  year: 2016
  ident: ref_103
  article-title: Fine mapping and identification of candidate genes for the sy-2 locus in a temperature-sensitive chili pepper (Capsicum chinense)
  publication-title: Theor. Appl. Genet.
  doi: 10.1007/s00122-016-2723-1
– volume: 105
  start-page: 5897
  year: 2008
  ident: ref_32
  article-title: An overlapping essential gene in the Potyviridae
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.0800468105
– volume: 25
  start-page: 237
  year: 2001
  ident: ref_43
  article-title: Technical advance: Tobacco rattle virus as a vector for analysis of gene function by silencing
  publication-title: Plant J.
  doi: 10.1046/j.0960-7412.2000.00942.x
– volume: 108
  start-page: 142
  year: 2018
  ident: ref_119
  article-title: Fine mapping of the dominant potyvirus resistance gene Pvr7 reveals a relationship with Pvr4 in Capsicum annuum
  publication-title: Phytopathology
  doi: 10.1094/PHYTO-07-17-0231-R
– volume: 64
  start-page: 1
  year: 2021
  ident: ref_127
  article-title: Double-stranded RNA confers resistance to pepper mottle virus in Nicotiana benthamiana
  publication-title: Appl. Biol. Chem.
  doi: 10.1186/s13765-020-00581-3
– volume: 5
  start-page: 110
  year: 2014
  ident: ref_33
  article-title: Intracellular coordination of potyviral RNA functions in infection
  publication-title: Front. Plant Sci.
– volume: 27
  start-page: 792
  year: 2019
  ident: ref_101
  article-title: RNA-targeted antiviral immunity: More than just RNA silencing
  publication-title: Trends Microbiol.
  doi: 10.1016/j.tim.2019.05.007
– volume: 149
  start-page: 234
  year: 2010
  ident: ref_36
  article-title: Stability of tobacco etch virus infectious clones in plasmid vectors
  publication-title: Virus Res.
  doi: 10.1016/j.virusres.2010.02.004
– ident: ref_18
  doi: 10.3390/v11121158
– volume: 13
  start-page: 1266
  year: 2000
  ident: ref_117
  article-title: The I gene of bean: A dosage-dependent allele conferring extreme resistance, hypersensitive resistance, or spreading vascular necrosis in response to the potyvirus bean common mosaic virus
  publication-title: Mol. Plant-Microbe Interact.
  doi: 10.1094/MPMI.2000.13.11.1266
– volume: 118
  start-page: 243
  year: 1997
  ident: ref_56
  article-title: Immunocytology shows the presence of tobacco etch virus P3 protein in nuclear inclusions
  publication-title: J. Struct. Biol.
  doi: 10.1006/jsbi.1997.3856
– ident: ref_50
  doi: 10.1371/journal.ppat.1003985
– ident: ref_20
  doi: 10.1371/journal.pone.0119639
– volume: 191
  start-page: 19
  year: 1992
  ident: ref_17
  article-title: The complete nucleotide sequence of pepper mottle virus genomic RNA: Comparison of the encoded polyprotein with those of other sequenced potyviruses
  publication-title: Virology
  doi: 10.1016/0042-6822(92)90162-I
– volume: 12
  start-page: 1305
  year: 2002
  ident: ref_121
  article-title: Patterns of positive selection in the complete NBS-LRR gene family of Arabidopsis thaliana
  publication-title: Genome Res.
  doi: 10.1101/gr.159402
– volume: 112
  start-page: 178
  year: 2005
  ident: ref_111
  article-title: Allele-specific CAPS markers based on point mutations in resistance alleles at the pvr1 locus encoding eIF4E in Capsicum
  publication-title: Theor. Appl. Genet.
  doi: 10.1007/s00122-005-0120-2
– volume: 5
  start-page: 321
  year: 1992
  ident: ref_28
  article-title: A comparison of pepper mottle virus with potato virus Y and evidence for their distinction
  publication-title: Potyvirus Taxonomy
  doi: 10.1007/978-3-7091-6920-9_34
– volume: 62
  start-page: 5013
  year: 2011
  ident: ref_73
  article-title: Is the 6 kDa tobacco etch viral protein a bona fide ERES marker?
  publication-title: J. Exp. Bot.
  doi: 10.1093/jxb/err200
– ident: ref_97
  doi: 10.3390/v12020217
– volume: 147
  start-page: 2365
  year: 2002
  ident: ref_99
  article-title: Amino acid substitutions within the Cys-rich domain of the tobacco etch potyvirus HC-Pro result in loss of transmissibility by aphids
  publication-title: Arch. Virol.
  doi: 10.1007/s00705-002-0884-5
– volume: 95
  start-page: 617
  year: 2011
  ident: ref_8
  article-title: First report of pepper mottle virus in bell pepper in Taiwan
  publication-title: Plant Dis.
  doi: 10.1094/PDIS-10-10-0721
– volume: 88
  start-page: 887
  year: 2006
  ident: ref_78
  article-title: Potyvirus terminal protein VPg, effector of host eukaryotic initiation factor eIF4E
  publication-title: Biochimie
  doi: 10.1016/j.biochi.2006.02.012
– ident: ref_58
  doi: 10.1371/journal.ppat.1000962
– volume: 31
  start-page: 103
  year: 2019
  ident: ref_128
  article-title: Transcriptomics of plant–virus interactions: A review
  publication-title: Theor. Exp. Plant Physiol.
  doi: 10.1007/s40626-019-00143-z
– volume: 23
  start-page: 653
  year: 2000
  ident: ref_85
  article-title: An Ry-mediated resistance response in potato requires the intact active site of the NIa proteinase from potato virus Y
  publication-title: Plant J.
  doi: 10.1046/j.1365-313x.2000.00834.x
– volume: 11
  start-page: 102
  year: 2020
  ident: ref_88
  article-title: The NIa-protease protein encoded by the Pepper mottle virus is a pathogenicity determinant and releases DNA methylation of Nicotiana benthamiana
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2020.00102
– volume: 25
  start-page: 1
  year: 2010
  ident: ref_108
  article-title: Loss of susceptibility as a novel breeding strategy for durable and broad-spectrum resistance
  publication-title: Mol. Breed.
  doi: 10.1007/s11032-009-9323-6
– volume: 11
  start-page: 40
  year: 2006
  ident: ref_106
  article-title: Translation initiation factors: A weak link in plant RNA virus infection
  publication-title: Trends Plant Sci.
  doi: 10.1016/j.tplants.2005.11.004
– volume: 86
  start-page: 186
  year: 2002
  ident: ref_6
  article-title: First report of pepper mottle virus in tomato
  publication-title: Plant Dis.
  doi: 10.1094/PDIS.2002.86.2.186C
– volume: 27
  start-page: 215
  year: 2014
  ident: ref_61
  article-title: The Potyviridae cylindrical inclusion helicase: A key multipartner and multifunctional protein
  publication-title: Mol. Plant-Microbe Interact.
  doi: 10.1094/MPMI-11-13-0333-CR
– volume: 666
  start-page: 123
  year: 2018
  ident: ref_129
  article-title: Transcriptome profiling using Illumina-and SMRT-based RNA-seq of hot pepper for in-depth understanding of genes involved in CMV infection
  publication-title: Gene
  doi: 10.1016/j.gene.2018.05.004
– volume: 81
  start-page: 12881
  year: 2007
  ident: ref_54
  article-title: HC-Pro protein of potato virus Y can interact with three Arabidopsis 20S proteasome subunits in planta
  publication-title: J. Virol.
  doi: 10.1128/JVI.00913-07
– volume: 96
  start-page: 240
  year: 2006
  ident: ref_14
  article-title: Synergistic disease in pepper caused by the mixed infection of cucumber mosaic virus and pepper mottle virus
  publication-title: Phytopathology
  doi: 10.1094/PHYTO-96-0240
– volume: 495
  start-page: 167
  year: 2016
  ident: ref_125
  article-title: Virus-induced gene silencing reveals signal transduction components required for the Pvr9-mediated hypersensitive response in Nicotiana benthamiana
  publication-title: Virology
  doi: 10.1016/j.virol.2016.05.011
– volume: 169
  start-page: 209
  year: 2015
  ident: ref_86
  article-title: Disruption of ethylene responses by turnip mosaic virus mediates suppression of plant defense against the green peach aphid vector
  publication-title: Plant Physiol.
  doi: 10.1104/pp.15.00332
– volume: 11
  start-page: 265
  year: 2010
  ident: ref_98
  article-title: Mutational analysis of interaction between coat protein and helper component-proteinase of Soybean mosaic virus involved in aphid transmission
  publication-title: Mol. Plant Pathol.
  doi: 10.1111/j.1364-3703.2009.00603.x
– volume: 213
  start-page: 886
  year: 2017
  ident: ref_120
  article-title: Divergent evolution of multiple virus-resistance genes from a progenitor in Capsicum spp.
  publication-title: New Phytol.
  doi: 10.1111/nph.14177
– volume: 17
  start-page: 943
  year: 2016
  ident: ref_72
  article-title: Protein composition of 6K2-induced membrane structures formed during potato virus A infection
  publication-title: Mol. Plant Pathol.
  doi: 10.1111/mpp.12341
– volume: 21
  start-page: 1194
  year: 2020
  ident: ref_93
  article-title: The cis-expression of the coat protein of turnip mosaic virus is essential for viral intercellular movement in plants
  publication-title: Mol. Plant Pathol.
  doi: 10.1111/mpp.12973
– volume: 97
  start-page: 183
  year: 1997
  ident: ref_107
  article-title: Proposed revision of nomenclature for potyvirusresistance genes in Capsicum
  publication-title: Euphytica
  doi: 10.1023/A:1003009721989
– volume: 13
  start-page: 1482
  year: 1994
  ident: ref_95
  article-title: Distinct functions of capsid protein in assembly and movement of tobacco etch potyvirus in plants
  publication-title: EMBO J.
  doi: 10.1002/j.1460-2075.1994.tb06403.x
– volume: 11
  start-page: 943
  year: 1998
  ident: ref_104
  article-title: Genetic mapping of the pvr1 locus in Capsicum spp. and evidence that distinct potyvirus resistance loci control responses that differ at the whole plant and cellular levels
  publication-title: Mol. Plant-Microbe Interact.
  doi: 10.1094/MPMI.1998.11.10.943
– volume: 80
  start-page: 2785
  year: 1999
  ident: ref_109
  article-title: Resistance of Capsicum annuum ‘Avelar’to pepper mottle potyvirus and alleviation of this resistance by co-infection with cucumber mosaic cucumovirus are associated with virus movement
  publication-title: J. Gen. Virol.
  doi: 10.1099/0022-1317-80-10-2785
– volume: 89
  start-page: 10208
  year: 1992
  ident: ref_45
  article-title: Tagging of plant potyvirus replication and movement by insertion of beta-glucuronidase into the viral polyprotein
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.89.21.10208
– volume: 27
  start-page: 1014
  year: 2014
  ident: ref_65
  article-title: Key mutations in the cylindrical inclusion involved in Lettuce mosaic virus adaptation to eIF4E-mediated resistance in lettuce
  publication-title: Mol. Plant-Microbe Interact.
  doi: 10.1094/MPMI-04-14-0111-R
– volume: 77
  start-page: 1335
  year: 1996
  ident: ref_51
  article-title: Potyviral HC-Pro: A multifunctional protein
  publication-title: J. Gen. Virol.
  doi: 10.1099/0022-1317-77-7-1335
– volume: 43
  start-page: 581
  year: 2005
  ident: ref_81
  article-title: Genetics of plant virus resistance
  publication-title: Annu. Rev. Phytopathol.
  doi: 10.1146/annurev.phyto.43.011205.141140
– volume: 146
  start-page: 15
  year: 2001
  ident: ref_39
  article-title: Nucleotide sequence and infectious cDNA clone of the L1 isolate of pea seed-borne mosaic potyvirus
  publication-title: Arch. Virol.
  doi: 10.1007/s007050170187
– volume: 16
  start-page: 777
  year: 2003
  ident: ref_59
  article-title: The dual role of the potyvirus P3 protein of turnip mosaic virus as a symptom and avirulence determinant in brassicas
  publication-title: Mol. Plant-Microbe Interact.
  doi: 10.1094/MPMI.2003.16.9.777
– volume: 5
  start-page: 526
  year: 2007
  ident: ref_113
  article-title: Ectopic expression of a recessive resistance gene generates dominant potyvirus resistance in plants
  publication-title: Plant Biotechnol. J.
  doi: 10.1111/j.1467-7652.2007.00262.x
– volume: 93
  start-page: 184
  year: 2012
  ident: ref_63
  article-title: The C terminus of lettuce mosaic potyvirus cylindrical inclusion helicase interacts with the viral VPg and with lettuce translation eukaryotic initiation factor 4E
  publication-title: J. Gen. Virol.
  doi: 10.1099/vir.0.035881-0
– volume: 69
  start-page: 348
  year: 2003
  ident: ref_3
  article-title: First report of pepper mottle virus on Capsicum annuum in Japan
  publication-title: J. Gen. Plant Pathol.
  doi: 10.1007/s10327-003-0059-6
– volume: 59
  start-page: 1
  year: 2021
  ident: ref_47
  article-title: Research advances in potyviruses: From the laboratory bench to the field
  publication-title: Annu. Rev. Phytopathol.
  doi: 10.1146/annurev-phyto-020620-114550
– volume: 42
  start-page: 392
  year: 2005
  ident: ref_115
  article-title: The pvr1 locus in Capsicum encodes a translation initiation factor eIF4E that interacts with tobacco etch virus VPg
  publication-title: Plant J.
  doi: 10.1111/j.1365-313X.2005.02381.x
– volume: 24
  start-page: 152
  year: 2008
  ident: ref_13
  article-title: Isolation and characterization of pepper mottle virus infecting tomato in Korea
  publication-title: Plant Pathol. J.
  doi: 10.5423/PPJ.2008.24.2.152
– volume: 12
  start-page: 1
  year: 2015
  ident: ref_44
  article-title: The multifunctional protein CI of potyviruses plays interlinked and distinct roles in viral genome replication and intercellular movement
  publication-title: Virol. J.
  doi: 10.1186/s12985-015-0369-2
– volume: 116
  start-page: 24056
  year: 2019
  ident: ref_76
  article-title: Structural studies of the eIF4E–VPg complex reveal a direct competition for capped RNA: Implications for translation
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.1904752116
– volume: 25
  start-page: 1489
  year: 2013
  ident: ref_100
  article-title: Plant immune responses against viruses: How does a virus cause disease?
  publication-title: Plant Cell
  doi: 10.1105/tpc.113.111658
– volume: 5
  start-page: eaaw3808
  year: 2019
  ident: ref_89
  article-title: Structural basis for the multitasking nature of the potato virus Y coat protein
  publication-title: Sci. Adv.
  doi: 10.1126/sciadv.aaw3808
– volume: 78
  start-page: 75
  year: 2014
  ident: ref_52
  article-title: Molecular evolution of viral multifunctional proteins: The case of potyvirus HC-Pro
  publication-title: J. Mol. Evol.
  doi: 10.1007/s00239-013-9601-0
– ident: ref_126
  doi: 10.3390/v13040688
– volume: 148
  start-page: 189
  year: 2003
  ident: ref_16
  article-title: The complete nucleotide sequence of pepper mottle virus-Florida RNA
  publication-title: Arch. Virol.
  doi: 10.1007/s00705-002-0915-2
– volume: 1
  start-page: 347
  year: 2011
  ident: ref_74
  article-title: The genome-linked protein VPg of plant viruses—a protein with many partners
  publication-title: Curr Opin Virol.
  doi: 10.1016/j.coviro.2011.09.010
– volume: 65
  start-page: 559
  year: 1975
  ident: ref_27
  article-title: Morphology, host range and serological relationships of pepper mottle virus
  publication-title: Phytopathology
  doi: 10.1094/Phyto-65-559
– volume: 87
  start-page: 2089
  year: 2006
  ident: ref_110
  article-title: Simultaneous mutations in translation initiation factors eIF4E and eIF(iso)4E are required to prevent pepper veinal mottle virus infection of pepper
  publication-title: J. Gen. Virol.
  doi: 10.1099/vir.0.81817-0
– volume: 91
  start-page: e01478-16
  year: 2017
  ident: ref_83
  article-title: The potyvirus silencing suppressor protein VPg mediates degradation of SGS3 via ubiquitination and autophagy pathways
  publication-title: J. Virol.
  doi: 10.1128/JVI.01478-16
– volume: 201
  start-page: 57
  year: 2014
  ident: ref_102
  article-title: A simple method for screening of plant NBS-LRR genes that confer a hypersensitive response to plant viruses and its application for screening candidate pepper genes against Pepper mottle virus
  publication-title: J. Virol. Methods
  doi: 10.1016/j.jviromet.2014.02.003
– volume: 22
  start-page: 155
  year: 2006
  ident: ref_12
  article-title: Biological, physical and cytological properties of pepper mottle virus-SNU1 and its RT-PCR detection
  publication-title: Plant Pathol. J.
  doi: 10.5423/PPJ.2006.22.2.155
– volume: 74
  start-page: 157
  year: 2001
  ident: ref_34
  article-title: Potyvirus proteins: A wealth of functions
  publication-title: Virus Res.
  doi: 10.1016/S0168-1702(01)00220-9
– volume: 5
  start-page: 1
  year: 2018
  ident: ref_130
  article-title: Global gene expression profiling for fruit organs and pathogen infections in the pepper, Capsicum annuum L.
  publication-title: Sci. Data
  doi: 10.1038/sdata.2018.103
– volume: 19
  start-page: 1207
  year: 2006
  ident: ref_123
  article-title: Global impact: Elucidating plant responses to viral infection
  publication-title: Mol. Plant-Microbe Interact.
  doi: 10.1094/MPMI-19-1207
– volume: 11
  start-page: 1207
  year: 2019
  ident: ref_68
  article-title: Mutagenesis scanning uncovers evolutionary constraints on tobacco etch potyvirus membrane-associated 6K2 protein
  publication-title: Genome Biol. Evol.
  doi: 10.1093/gbe/evz069
– volume: 11
  start-page: 1098
  year: 2020
  ident: ref_22
  article-title: Genome editing of eIF4E1 in tomato confers resistance to pepper mottle virus
  publication-title: Front. Plant Sci.
  doi: 10.3389/fpls.2020.01098
– volume: 93
  start-page: 12400
  year: 1996
  ident: ref_38
  article-title: Intron insertion facilitates amplification of cloned virus cDNA in Escherichia coli while biological activity is reestablished after transcription in vivo
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.93.22.12400
– volume: 56
  start-page: 586
  year: 1972
  ident: ref_2
  article-title: Plant disease reporter naturally occurring pepper virus strains in south Florida
  publication-title: Plant Dis. Rep.
– volume: 115
  start-page: 2012
  year: 2018
  ident: ref_10
  article-title: Seed transmissibility of pepper mottle virus: Survival of virus
  publication-title: Curr. Sci.
– volume: 23
  start-page: 1460
  year: 2010
  ident: ref_49
  article-title: Involvement of the P1 cistron in overcoming eIF4E-mediated recessive resistance against clover yellow vein virus in pea
  publication-title: Mol. Plant-Microbe Interact.
  doi: 10.1094/MPMI-11-09-0277
– volume: 69
  start-page: 3668
  year: 1995
  ident: ref_48
  article-title: Evidence that the potyvirus P1 proteinase functions in trans as an accessory factor for genome amplification
  publication-title: J. Virol.
  doi: 10.1128/jvi.69.6.3668-3674.1995
– ident: ref_69
  doi: 10.3390/v12010077
– volume: 79
  start-page: 3119
  year: 1998
  ident: ref_53
  article-title: Mutations in the potyvirus helper component protein: Effects on interactions with virions and aphid stylets
  publication-title: J. Gen. Virol.
  doi: 10.1099/0022-1317-79-12-3119
– volume: 283
  start-page: 1340
  year: 2008
  ident: ref_77
  article-title: Potyvirus genome-linked protein, VPg, directly affects wheat germ in vitro translation: Interactions with translation initiation factors eIF4F and eIFiso4F
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M703356200
– volume: 265
  start-page: 26
  year: 2019
  ident: ref_23
  article-title: A plant intron enhances the performance of an infectious clone in planta
  publication-title: J. Virol. Methods
  doi: 10.1016/j.jviromet.2018.12.012
– volume: 14
  start-page: 393
  year: 1998
  ident: ref_62
  article-title: Genetic evidence for an essential role for potyvirus CI protein in cell-to-cell movement
  publication-title: Plant J.
  doi: 10.1046/j.1365-313X.1998.00120.x
– volume: 108
  start-page: 165
  year: 2020
  ident: ref_90
  article-title: Potyviral coat protein and genomic RNA: A striking partnership leading virion assembly and more
  publication-title: Adv. Virus Res.
  doi: 10.1016/bs.aivir.2020.09.001
– volume: 206
  start-page: 1007
  year: 1995
  ident: ref_91
  article-title: Capsid protein determinants involved in cell-to-cell and long distance movement of tobacco etch potyvirus
  publication-title: Virology
  doi: 10.1006/viro.1995.1023
– volume: 90
  start-page: 1427
  year: 2008
  ident: ref_79
  article-title: Turnip mosaic virus VPg interacts with Arabidopsis thaliana eIF (iso) 4E and inhibits in vitro translation
  publication-title: Biochimie
  doi: 10.1016/j.biochi.2008.03.013
– volume: 144
  start-page: 83
  year: 2009
  ident: ref_4
  article-title: Molecular characterization of Korean pepper mottle virus isolates and its relationship to symptom variations
  publication-title: Virus Res.
  doi: 10.1016/j.virusres.2009.04.003
– ident: ref_1
  doi: 10.1002/9780470015902.a0000755.pub3
– volume: 65
  start-page: 110
  year: 1975
  ident: ref_11
  article-title: Transmission of pepper mottle virus from susceptible and resistant pepper cultivars
  publication-title: Phytopathology
  doi: 10.1094/Phyto-65-110
– volume: 374
  start-page: 217
  year: 2008
  ident: ref_82
  article-title: Heat shock 70 protein interaction with turnip mosaic virus RNA-dependent RNA polymerase within virus-induced membrane vesicles
  publication-title: Virology
  doi: 10.1016/j.virol.2007.12.014
– volume: 5
  start-page: 307
  year: 2014
  ident: ref_116
  article-title: Dominant resistance against plant viruses
  publication-title: Front. Plant Sci.
– volume: 8
  start-page: 14493
  year: 2017
  ident: ref_87
  article-title: A viral protease relocalizes in the presence of the vector to promote vector performance
  publication-title: Nat. Commun.
  doi: 10.1038/ncomms14493
– volume: 16
  start-page: 1
  year: 2015
  ident: ref_124
  article-title: RNA-Seq analysis of resistant and susceptible potato varieties during the early stages of potato virus Y infection
  publication-title: BMC Genom.
  doi: 10.1186/s12864-015-1666-2
– volume: 481
  start-page: 113
  year: 2015
  ident: ref_21
  article-title: Molecular characterization of Pvr9 that confers a hypersensitive response to pepper mottle virus (a potyvirus) in Nicotiana benthamiana
  publication-title: Virology
  doi: 10.1016/j.virol.2015.02.052
– volume: 9
  start-page: 666
  year: 2018
  ident: ref_84
  article-title: Plant viral proteases: Beyond the role of peptide cutters
  publication-title: Front. Plant Sci.
  doi: 10.3389/fpls.2018.00666
– volume: 25
  start-page: 1307
  year: 2012
  ident: ref_118
  article-title: The requirement of multiple defense genes in soybean Rsv1–mediated extreme resistance to soybean mosaic virus
  publication-title: Mol. Plant-Microbe Interact.
  doi: 10.1094/MPMI-02-12-0046-R
– volume: 162
  start-page: 3717
  year: 2017
  ident: ref_24
  article-title: A pepper mottle virus-based vector enables systemic expression of endoglucanase D in non-transgenic plants
  publication-title: Arch. Virol.
  doi: 10.1007/s00705-017-3539-2
– volume: 10
  start-page: 109
  year: 2009
  ident: ref_64
  article-title: Involvement of the cylindrical inclusion (CI) protein in the overcoming of an eIF4E-mediated resistance against lettuce mosaic potyvirus
  publication-title: Mol. Plant Pathol.
  doi: 10.1111/j.1364-3703.2008.00513.x
– volume: 155
  start-page: 487
  year: 2011
  ident: ref_29
  article-title: Development of infectious transcripts from full-length and GFP-tagged cDNA clones of Pepper mottle virus and stable systemic expression of GFP in tobacco and pepper
  publication-title: Virus Res.
  doi: 10.1016/j.virusres.2010.12.004
– volume: 85
  start-page: 9210
  year: 2011
  ident: ref_75
  article-title: Potyviral VPg enhances viral RNA translation and inhibits reporter mRNA translation in planta
  publication-title: J. Virol.
  doi: 10.1128/JVI.00052-11
– volume: 274
  start-page: 346
  year: 2005
  ident: ref_112
  article-title: The recessive potyvirus resistance gene pot-1 is the tomato orthologue of the pepper pvr2-eIF4E gene
  publication-title: Mol. Genet. Genom.
  doi: 10.1007/s00438-005-0003-x
– volume: 25
  start-page: 417
  year: 2009
  ident: ref_19
  article-title: Effects of recombination on the pathogenicity and evolution of pepper mottle virus
  publication-title: Plant Pathol. J.
  doi: 10.5423/PPJ.2009.25.4.417
– volume: 14
  start-page: 439
  year: 2013
  ident: ref_46
  article-title: Potato virus Y: A major crop pathogen that has provided major insights into the evolution of viral pathogenicity
  publication-title: Mol. Plant Pathol.
  doi: 10.1111/mpp.12024
– volume: 89
  start-page: 6695
  year: 2015
  ident: ref_67
  article-title: The vesicle-forming 6K2 protein of turnip mosaic virus interacts with the COPII coatomer Sec24a for viral systemic infection
  publication-title: J. Virol.
  doi: 10.1128/JVI.00503-15
– volume: 89
  start-page: 4237
  year: 2015
  ident: ref_92
  article-title: Cotranslational coat protein-mediated inhibition of potyviral RNA translation
  publication-title: J. Virol.
  doi: 10.1128/JVI.02915-14
– volume: 96
  start-page: 917
  year: 2012
  ident: ref_7
  article-title: First report of pepper mottle virus infecting tomato in Hawaii
  publication-title: Plant Dis.
  doi: 10.1094/PDIS-02-12-0147-PDN
– volume: 85
  start-page: 6784
  year: 2011
  ident: ref_55
  article-title: Helper component proteinase of the genus Potyvirus is an interaction partner of translation initiation factors eIF (iso) 4E and eIF4E and contains a 4E binding motif
  publication-title: J. Virol.
  doi: 10.1128/JVI.00485-11
– volume: 13
  start-page: 795
  year: 2012
  ident: ref_80
  article-title: Eukaryotic translation initiation factor 4E-mediated recessive resistance to plant viruses and its utility in crop improvement
  publication-title: Mol. Plant Pathol.
  doi: 10.1111/j.1364-3703.2012.00791.x
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Snippet Pepper mottle virus (PepMoV) is a destructive pathogen that infects various solanaceous plants, including pepper, bell pepper, potato, and tomato. In this...
(PepMoV) is a destructive pathogen that infects various solanaceous plants, including pepper, bell pepper, potato, and tomato. In this review, we summarize...
Pepper mottle virus (PepMoV) is a destructive pathogen that infects various solanaceous plants, including pepper, bell pepper, potato, and tomato. In this...
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StartPage 1930
SubjectTerms Cloning
E coli
Genes, vpr
Genetic analysis
Genetic diversity
genetic variation
Genomes
Host Microbial Interactions - genetics
Host plants
Infections
Lycopersicon esculentum - genetics
Lycopersicon esculentum - virology
Molecular modelling
Pathogens
pepper
Pepper mottle virus
pepper resistance gene
Plant Diseases - genetics
Plant Diseases - virology
Plasmids
potatoes
Potyvirus
Potyvirus - genetics
Potyvirus - physiology
Proteins
reverse genetics
Review
Roles
Solanum tuberosum - genetics
Solanum tuberosum - virology
sweet peppers
tomatoes
transcriptomics
Viral infections
Viruses
virus–host interaction
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Title Pepper Mottle Virus and Its Host Interactions: Current State of Knowledge
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