Chitosan-based biocompatible dressing for treatment of recalcitrant lesions of cutaneous leishmaniasis: A pilot clinical study

• Published in: Indian journal of dermatology, venereology, and leprology Vol. 85; no. 6; pp. 609 - 614
• Main Authors: Abdollahimajd, Fahimeh, Moravvej, Hamideh, Dadkhahfar, Sahar, Mahdavi, Hamid, Mohebali, Mehdi, Mirzadeh, Hamid
• Format: Journal Article
• Language: English
• Published: United States Wolters Kluwer India Pvt. Ltd 01.11.2019; Medknow Publications and Media Pvt. Ltd; Scientific Scholar
• Subjects: Adolescent; Adult; Aged; Bandages; Biocompatibility; Biocompatible Materials - administration & dosage; Care and treatment; Child; Chitin; Chitosan - administration & dosage; Clinical trials; Cutaneous leishmaniasis; Female; Follow-Up Studies; Humans; Leishmaniasis; Leishmaniasis, Cutaneous - diagnosis; Leishmaniasis, Cutaneous - therapy; Male; Meglumine antimoniate; Middle Aged; Nanoparticles; Parasites; Parasitic diseases; Patients; Pilot Projects; Safety and security measures; Skin diseases; Statistics; Tropical diseases; Wound healing; Wound Healing - physiology; Young Adult; Zoonoses; Iran; chitosan; dressing; cutaneous leishmaniasis; humans; topical treatment; Biocompatible materials

Background: Chitosan has a biocompatible, biodegradable and nontoxic nature. The effectiveness of nano-chitosan films in the treatment of cutaneous leishmaniasis has been confirmed previously in susceptible laboratory animals. Aims: The aim of this study is to evaluate the safety and efficacy of a c...