Alanine aminotransferase-based algorithms of liver stiffness measurement by transient elastography (Fibroscan) for liver fibrosis in chronic hepatitis B

• Published in: Journal of viral hepatitis Vol. 16; no. 1; pp. 36 - 44
• Main Authors: Chan, H. L.-Y., Wong, G. L.-H., Choi, P. C.-L., Chan, A. W.-H., Chim, A. M.-L., Yiu, K. K.-L., Chan, F. K.-L., Sung, J. J.-Y., Wong, V. W.-S.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.01.2009
• Subjects: Adult; Alanine Transaminase - blood; Elasticity Imaging Techniques; Female; hepatitis B virus; Hepatitis B, Chronic - pathology; histology; Humans; Liver - pathology; liver biopsy; liver cirrhosis; Liver Cirrhosis - diagnosis; Male; Middle Aged; Retrospective Studies; ROC Curve; Severity of Illness Index

The aim of this study is to know the liver stiffness measurement (LSM) cutoffs for different stages of liver fibrosis in chronic hepatitis B (CHB) and to investigate the effect of alanine aminotransferase (ALT) on LSM. We prospectively studied consecutive CHB patients undergoing liver biopsy and tra...