HIV-mediated immune aging in young adults infected perinatally or during childhood

• Published in: AIDS (London) Vol. 33; no. 11; pp. 1705 - 1710
• Main Authors: Fastenackels, Solène, Sauce, Delphine, Vigouroux, Corinne, Avettand-Fènoël, Véronique, Bastard, Jean-Philippe, Fellahi, Soraya, Nailler, Laura, Arezes, Elisa, Rouzioux, Christine, Warszawski, Josiane, Viard, Jean Paul, Appay, Victor
• Format: Journal Article
• Language: English
• Published: England Copyright Wolters Kluwer Health, Inc 01.09.2019; Wolters Kluwer
• Subjects: Human health and pathology; Immunology; Infectious diseases; Life Sciences; Immunosenescence; lymphocytes; antiretroviral therapy; age

BACKGROUND:HIV-infected patients progressing towards disease present a premature immune aging profile, characterized by the exhaustion of lymphopoiesis. The development of these anomalies may be prevented in young HIV-infected patients owing to their robust immune resources and lymphocyte regenerati...