Skeletal Microstructure and Estimated Bone Strength Improve Following Parathyroidectomy in Primary Hyperparathyroidism

• Published in: The journal of clinical endocrinology and metabolism Vol. 103; no. 1; pp. 196 - 205
• Main Authors: Cusano, Natalie E, Rubin, Mishaela R, Silva, Barbara C, Tay, Yu-Kwang Donovan, Williams, John M, Agarwal, Sanchita, Omeragic, Beatriz, Guo, X Edward, Bilezikian, John P
• Format: Journal Article
• Language: English
• Published: United States Copyright Oxford University Press 01.01.2018; Oxford University Press; Endocrine Society
• Subjects: Adult; Aged; Aged, 80 and over; Bone Density; Bone mineral density; Bone strength; Cancellous bone; Clinical s; Cohort Studies; Computed tomography; Cortical bone; Female; Finite Element Analysis; Finite element method; Follow-Up Studies; Fractures; Fractures, Bone - prevention & control; Humans; Hyperparathyroidism; Hyperparathyroidism, Primary - diagnostic imaging; Hyperparathyroidism, Primary - pathology; Hyperparathyroidism, Primary - surgery; Male; Middle Aged; Parathyroidectomy; Prognosis; Radius; Tibia; Tomography, X-Ray Computed - methods

High-resolution peripheral quantitative computed tomography (HRpQCT) is a noninvasive imaging technology that can provide insight into skeletal microstructure and strength. In asymptomatic primary hyperparathyroidism (PHPT), HRpQCT imaging has demonstrated both decreased cortical and trabecular indi...