Left Ventricular Thrombus of Unknown Etiology in a Patient With COVID-19 Disease With No Significant Medical History
The incidence of left ventricular thrombus is relatively low. Ventricular thrombi typically manifest in patients with reduced ejection fraction and post myocardial infarction [1]. The impact of COVID-19's hypercoagulability state is presented here. A 44 year old male who contracted COVID-19, pr...
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| Published in | Cardiovascular revascularization medicine Vol. 40; pp. 329 - 331 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
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United States
Elsevier Inc
01.07.2022
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| Abstract | The incidence of left ventricular thrombus is relatively low. Ventricular thrombi typically manifest in patients with reduced ejection fraction and post myocardial infarction [1]. The impact of COVID-19's hypercoagulability state is presented here.
A 44 year old male who contracted COVID-19, progressed to moderate disease requiring inpatient treatment with supplemental oxygen. During the course of the hospital stay, while receiving National Institutes of Health guideline directed thromboembolism prophylaxis for COVID-19 infected patients [2], the patient developed a left ventricular thrombus which consequently embolized and occluded the left anterior descending and left circumflex coronary arteries requiring rheolytic thrombectomy.
•Seemingly healthymale adult contracts COVID-19 becomes hospitalized for respiratory failure due to moderate-severe COVID disease•While on guideline directed venous thromboembolism prophylaxis, patient develops left ventricular thrombus•Emboli from thrombous occlude left anterior descending coronary artery and near-occlude left circumflex coronary artery•Patient requires mechanical thrombectomy•Patient discharged with no known impact on cardiac function |
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| AbstractList | AbstractThe incidence of left ventricular thrombus is relatively low. Ventricular thrombi typically manifest in patients with reduced ejection fraction and post myocardial infarction [1]. The impact of COVID-19's hypercoagulability state is presented here. A 44 year old male who contracted COVID-19, progressed to moderate disease requiring inpatient treatment with supplemental oxygen. During the course of the hospital stay, while receiving National Institutes of Health guideline directed thromboembolism prophylaxis for COVID-19 infected patients [2], the patient developed a left ventricular thrombus which consequently embolized and occluded the left anterior descending and left circumflex coronary arteries requiring rheolytic thrombectomy. The incidence of left ventricular thrombus is relatively low. Ventricular thrombi typically manifest in patients with reduced ejection fraction and post myocardial infarction [1]. The impact of COVID-19's hypercoagulability state is presented here. A 44 year old male who contracted COVID-19, progressed to moderate disease requiring inpatient treatment with supplemental oxygen. During the course of the hospital stay, while receiving National Institutes of Health guideline directed thromboembolism prophylaxis for COVID-19 infected patients [2], the patient developed a left ventricular thrombus which consequently embolized and occluded the left anterior descending and left circumflex coronary arteries requiring rheolytic thrombectomy. The incidence of left ventricular thrombus is relatively low. Ventricular thrombi typically manifest in patients with reduced ejection fraction and post myocardial infarction [1]. The impact of COVID-19's hypercoagulability state is presented here. A 44 year old male who contracted COVID-19, progressed to moderate disease requiring inpatient treatment with supplemental oxygen. During the course of the hospital stay, while receiving National Institutes of Health guideline directed thromboembolism prophylaxis for COVID-19 infected patients [2], the patient developed a left ventricular thrombus which consequently embolized and occluded the left anterior descending and left circumflex coronary arteries requiring rheolytic thrombectomy. •Seemingly healthymale adult contracts COVID-19 becomes hospitalized for respiratory failure due to moderate-severe COVID disease•While on guideline directed venous thromboembolism prophylaxis, patient develops left ventricular thrombus•Emboli from thrombous occlude left anterior descending coronary artery and near-occlude left circumflex coronary artery•Patient requires mechanical thrombectomy•Patient discharged with no known impact on cardiac function The incidence of left ventricular thrombus is relatively low. Ventricular thrombi typically manifest in patients with reduced ejection fraction and post myocardial infarction [1]. The impact of COVID-19's hypercoagulability state is presented here. A 44 year old male who contracted COVID-19, progressed to moderate disease requiring inpatient treatment with supplemental oxygen. During the course of the hospital stay, while receiving National Institutes of Health guideline directed thromboembolism prophylaxis for COVID-19 infected patients [2], the patient developed a left ventricular thrombus which consequently embolized and occluded the left anterior descending and left circumflex coronary arteries requiring rheolytic thrombectomy. The incidence of left ventricular thrombus is relatively low. Ventricular thrombi typically manifest in patients with reduced ejection fraction and post myocardial infarction [1]. The impact of COVID-19's hypercoagulability state is presented here. A 44 year old male who contracted COVID-19, progressed to moderate disease requiring inpatient treatment with supplemental oxygen. During the course of the hospital stay, while receiving National Institutes of Health guideline directed thromboembolism prophylaxis for COVID-19 infected patients [2], the patient developed a left ventricular thrombus which consequently embolized and occluded the left anterior descending and left circumflex coronary arteries requiring rheolytic thrombectomy.The incidence of left ventricular thrombus is relatively low. Ventricular thrombi typically manifest in patients with reduced ejection fraction and post myocardial infarction [1]. The impact of COVID-19's hypercoagulability state is presented here. A 44 year old male who contracted COVID-19, progressed to moderate disease requiring inpatient treatment with supplemental oxygen. During the course of the hospital stay, while receiving National Institutes of Health guideline directed thromboembolism prophylaxis for COVID-19 infected patients [2], the patient developed a left ventricular thrombus which consequently embolized and occluded the left anterior descending and left circumflex coronary arteries requiring rheolytic thrombectomy. |
| Author | Thotakura, Sudhir Muthu, Krishnakumar Myers, Douglas Russell, Joseph Wagoner, Michael DuPont, James |
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| Cites_doi | 10.1001/jama.2020.13372 10.1056/NEJMoa2105911 10.1016/j.jacc.2019.01.031 10.1016/j.amjcard.2010.06.043 10.1182/blood.2020006000 10.1111/jth.14888 10.1016/S2665-9913(20)30121-1 10.1038/s41598-021-83466-9 |
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| Keywords | COVID-19 Left ventricular thrombosis Arterial thromboembolism |
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| License | Copyright © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
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| References | Solheim, Seljeflot, Lunde, Bjørnerheim, Aakhus, Forfang, Arnesen (bb0015) 2010; 106 Connors, Levy (bb0025) 2020; 135 Middeldorp, Coppens, van Haaps, Foppen, Vlaar, Müller (bb0035) 2020; 18 McGonagle, O’Donnell, Sharif, Emery, Bridgewood (bb0030) 2020; 2 (bb0040) 2021; 385 bb0045 bb0010 Bilaloglu, Aphinyanaphongs, Jones, Iturrate, Hochman, Berger (bb0020) 2020; 324 Smilowitz, Subashchandran, Newman, Barfield, Maldonado, Brosnahan (bb0050) 2021; 11 McCarthy, Murphy, Venkateswaran, Singh, Chang, Joice (bb0005) 2019; 73 Connors (10.1016/j.carrev.2022.03.010_bb0025) 2020; 135 Solheim (10.1016/j.carrev.2022.03.010_bb0015) 2010; 106 McCarthy (10.1016/j.carrev.2022.03.010_bb0005) 2019; 73 McGonagle (10.1016/j.carrev.2022.03.010_bb0030) 2020; 2 Bilaloglu (10.1016/j.carrev.2022.03.010_bb0020) 2020; 324 (10.1016/j.carrev.2022.03.010_bb0040) 2021; 385 Middeldorp (10.1016/j.carrev.2022.03.010_bb0035) 2020; 18 Smilowitz (10.1016/j.carrev.2022.03.010_bb0050) 2021; 11 |
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| Snippet | The incidence of left ventricular thrombus is relatively low. Ventricular thrombi typically manifest in patients with reduced ejection fraction and post... AbstractThe incidence of left ventricular thrombus is relatively low. Ventricular thrombi typically manifest in patients with reduced ejection fraction and... |
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| SubjectTerms | Arterial thromboembolism Cardiovascular Case Report COVID-19 Left ventricular thrombosis |
| Title | Left Ventricular Thrombus of Unknown Etiology in a Patient With COVID-19 Disease With No Significant Medical History |
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