Human brain cancer studied by resonance Raman spectroscopy

• Published in: Journal of biomedical optics Vol. 17; no. 11; pp. 116021 - 2/3
• Main Authors: Zhou, Yan, Liu, Cheng-Hui, Sun, Yi, Pu, Yang, Boydston-White, Susie, Liu, Yulong, Alfano, Robert R.
• Format: Journal Article
• Language: English
• Published: United States Society of Photo-Optical Instrumentation Engineers 01.11.2012
• Subjects: Adult; Brain; Brain Neoplasms - diagnosis; Cancer; Confocal; Cranial Nerve Neoplasms - diagnosis; Diagnostic systems; Excitation; Female; Glioblastoma - diagnosis; Human; Humans; Male; Meningeal Neoplasms - diagnosis; Meningioma - diagnosis; Middle Aged; Neuroma, Acoustic - diagnosis; Optical Phenomena; Pituitary Neoplasms - diagnosis; Principal Component Analysis; Research Papers: Imaging; Spectra; Spectrum Analysis, Raman - methods; Support Vector Machine; Support vector machines

The resonance Raman (RR) spectra of six types of human brain tissues are examined using a confocal micro-Raman system with 532-nm excitation in vitro. Forty-three RR spectra from seven subjects are investigated. The spectral peaks from malignant meningioma, stage III (cancer), benign meningioma (ben...