Rhodococcus rhodochrous IEGM 1362 Immobilized in Macroporous PVA Cryogel as an Effective Biocatalyst for the Production of Bioactive (–)-Isopulegol Compounds

• Published in: Pharmaceuticals (Basel, Switzerland) Vol. 18; no. 6; p. 839
• Main Authors: Maltseva, Polina Y., Plotnitskaya, Natalia A., Chudinova, Alexandra A., Ilyina, Irina V., Volcho, Konstantin P., Salakhutdinov, Nariman F., Ivshina, Irina B.
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 03.06.2025; MDPI
• Subjects: (–)-isopulegol; Acids; Actinomycetes; Adaptation; Antimicrobial agents; Biocatalysts; Biotransformation; By products; Chemical properties; Enzymes; Genetic aspects; Health aspects; immobilization; Metabolites; Monoterpenes; Oxidation; Physiological aspects; Polyvinyl alcohol; Rhodococcus; Scanning electron microscopy; Russia; Rhodococcus; biotransformation; (–)-isopulegol; immobilization; polyvinyl alcohol

Background: This study explored the biotransformation of (–)-isopulegol using immobilized cells of Rhodococcus rhodochrous IEGM 1362 to optimize the production of new bioactive compounds. Methods: An efficient biocatalyst based on R. rhodochrous IEGM 1362 cells immobilized in a macroporous polyvinyl...