Blood flow-restricted strength training displays high functional and biological efficacy in women: a within-subject comparison with high-load strength training

• Published in: American journal of physiology. Regulatory, integrative and comparative physiology Vol. 309; no. 7; pp. R767 - R779
• Main Authors: Ellefsen, Stian, Hammarström, Daniel, Strand, Tor A., Zacharoff, Erika, Whist, Jon E., Rauk, Irene, Nygaard, Håvard, Vegge, Geir, Hanestadhaugen, Marita, Wernbom, Mathias, Cumming, Kristoffer T., Rønning, Roar, Raastad, Truls, Rønnestad, Bent R.
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.10.2015
• Subjects: Anatomy, Cross-Sectional; Biopsy; Blood pressure; Cell Count; composition; Exercise; Female; Fysiologi och anatomi; Gene Expression; Genes; Growth hormones; heavy-chain; heavy-load strength training; hormone; Hormones - blood; human skeletal-muscle; Humans; Immunohistochemistry; Leg - physiology; low-load blood flow-restricted training; Magnetic Resonance Imaging; messenger-rna expression; Muscle Fibers, Skeletal - physiology; Muscle Strength - genetics; Muscle Strength - physiology; muscle strength and mass; Muscle, Skeletal - anatomy & histology; Muscle, Skeletal - cytology; Muscle, Skeletal - physiology; older men; Orthopaedics; Ortopedi; Physical Activity and Inactivity; Physiology; Physiology and Anatomy; protein-synthesis; Regional Blood Flow - physiology; resistance exercise; Resistance Training - methods; responses; RNA, Messenger - analysis; RNA, Messenger - biosynthesis; satellite cells; Tourniquets; Training; vascular occlusion; Young Adult; low-load blood flow-restricted training; muscle strength and mass; heavy-load strength training; muscle fiber; gene expression

Limited data exist on the efficacy of low-load blood flow-restricted strength training (BFR), as compared directly to heavy-load strength training (HST). Here, we show that 12 wk of twice-a-week unilateral BFR [30% of one repetition maximum (1RM) to exhaustion] and HST (6-10RM) of knee extensors pro...