Anesthetic management of HELLP syndrome complicating primary antiphospholipid syndrome -A case report

• Published in: Korean journal of anesthesiology Vol. 62; no. 6; pp. 575 - 578
• Main Authors: Jo, Youn Yi, Lee, Kyung Cheon, Kim, Hong Soon, Bae, Hyun Kyung, Chang, Young Jin
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Society of Anesthesiologists 01.06.2012; Korean Society of Anesthesiologists; 대한마취통증의학회
• Subjects: antiphospholipid syndrome; Case Report; eclampsia; hellp; 마취과학; HELLP; Eclampsia; Antiphospholipid syndrome
• ISSN: 2005-6419; 2005-7563; 2005-7563
• DOI: 10.4097/kjae.2012.62.6.575

Antiphospholipid syndrome (APS) is defined as an autoimmune disorder characterized by recurrent thrombosis or obstetrical morbidity. A 29-year-old woman who was diagnosed with APS underwent emergency cesarean delivery at 23 weeks' gestation. She had a seizure attack and her laboratory findings were: AST/ALT 1459/1108 IU/L, LDH 1424 IU/L, 30% hematocrit, a platelet count of 43 × 10(3)/ml and urine protein (4+). We describe the anesthetic experience of catastrophic HELLP syndrome with antiphospholipid syndrome and we review the relevant literature.