Impact of subthalamic nucleus stimulation on the initiation of gait in Parkinson's disease

• Published in: Experimental brain research Vol. 172; no. 4; pp. 519 - 532
• Main Authors: CRENNA, P, CARPINELLA, I, RABUFFETTI, M, RIZZONE, M, LOPIANO, L, LANOTTE, M, FERRARIN, M
• Format: Journal Article
• Language: English
• Published: Berlin Springer 01.07.2006; Springer Nature B.V
• Subjects: Aged; Analysis of Variance; Biological and medical sciences; Biomechanical Phenomena; Deep Brain Stimulation - methods; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Electromyography - methods; Female; Fundamental and applied biological sciences. Psychology; Gait - radiation effects; Humans; Male; Medical sciences; Middle Aged; Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration; Neurology; Parkinson Disease - physiopathology; Parkinson Disease - therapy; Postural Balance - physiology; Postural Balance - radiation effects; Posture - physiology; Subthalamic Nucleus - physiopathology; Subthalamic Nucleus - radiation effects; Vertebrates: nervous system and sense organs; Parkinson's disease; Gait; Deep brain stimulation; Central nervous system; Lower limb; Parkinson disease; Anticipation; Synergism; Posture; Osteoarticular system; Initiation of gait; Kinematics; Degenerative disease; Muscle; Subthalamic nucleus; Human; Nervous system diseases; Idiopathic; Anticipatory postural adjustments; Joint; Motor control; Hip; Cerebral disorder; Central nervous system disease; Extrapyramidal syndrome

The effects of subthalamic nucleus (STN) stimulation on the anticipatory postural actions associated with the initiation of gait were studied in ten patients with idiopathic Parkinson's disease undergoing therapeutic deep brain stimulation. Kinematic, dynamic and electromyographic analysis was...