The clock gene Per1 is necessary in the retrosplenial cortex—but not in the suprachiasmatic nucleus—for incidental learning in young and aging male mice - Brunswick, Chad A.; Baldwin, Derek J.; Bodinayake, Kasuni K.; McKenna, Alexandria R.; Lo, Chen-Yu; Bellfy, Lauren; Urban, Mark W.; Stuart, Emily M.; Murakami, Shoko; Smies, Chad W.; Kwapis, Janine L. (Neurobiology of aging, 2023)
Keywords: Aging; Aging - genetics; Animals; Brain - metabolism; Circadian Clocks - genetics; Circadian Rhythm - genetics; Cognitive decline; Gyrus Cinguli - metabolism; Incidental learning; Male; Mice; Per1; Period Circadian Proteins - genetics; Period Circadian Proteins - metabolism; Retrosplenial cortex; Suprachiasmatic nucleus; Suprachiasmatic Nucleus - metabolism; Transcription Factors - metabolism; Suprachiasmatic nucleus; TTFL; RSC; DH; BMAL; HSV; IEG; Cry; Incidental learning; Cognitive decline; Per1; OLM; CREB; sgRNA; Aging; Retrosplenial cortex; ZT; CLOCK; SCN