Quaternary ammonium-based biomedical materials: State-of-the-art, toxicological aspects and antimicrobial resistance

• Published in: Progress in polymer science Vol. 71; pp. 53 - 90
• Main Authors: Jiao, Yang, Niu, Li-na, Ma, Sai, Li, Jing, Tay, Franklin R., Chen, Ji-hua
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 01.08.2017; Elsevier
• Subjects: Antimicrobial resistance; Antimicrobial surfaces; Quaternary ammonium compounds; Toxicological aspects; Toxicological aspects; Quaternary ammonium compounds; Antimicrobial surfaces; Antimicrobial resistance

Microbial infections affect humans worldwide. Many quaternary ammonium compounds have been synthesized that are not only antibacterial, but also possess antifungal, antiviral and anti-matrix metalloproteinase capabilities. Incorporation of quaternary ammonium moieties into polymers represents one of...