Pancreatic cancer stem cell proliferation is strongly inhibited by diethyldithiocarbamate-copper complex loaded into hyaluronic acid decorated liposomes - Marengo, Alessandro; Forciniti, Stefania; Dando, Ilaria; Dalla Pozza, Elisa; Stella, Barbara; Tsapis, Nicolas; Yagoubi, Najet; Fanelli, Giuseppina; Fattal, Elias; Heeschen, Christopher; Palmieri, Marta; Arpicco, Silvia (Biochimica et biophysica acta. General subjects, 2019)
Keywords: acetylcysteine; adenocarcinoma; antineoplastic activity; CD44; cell lines; cell proliferation; copper nanoparticles; cryo-electron microscopy; crystals; Diethyldithiocarbamate/copper complex; encapsulation; Galenic pharmacology; Hyaluronic acid; in vitro studies; Life Sciences; Liposomes; mechanism of action; metastasis; nanomedicine; neoplasm cells; neutralization tests; Pancreatic cancer stem cells; pancreatic neoplasms; patients; PDAC patient-derived cells; Pharmaceutical sciences; relapse; stem cells; therapeutics; transmission electron microscopy; Pancreatic cancer stem cells; Liposomes; Diethyldithiocarbamate/copper complex; Hyaluronic acid; CD44; PDAC patient-derived cells