Modification to the Capsid of the Adenovirus Vector That Enhances Dendritic Cell Infection and Transgene-Specific Cellular Immune Responses

• Published in: Journal of Virology Vol. 78; no. 5; pp. 2572 - 2580
• Main Authors: WORGALL, Stefan, BUSCH, Annette, KOVESDI, Imi, CRYSTAL, Ronald G, RIVARA, Michael, BONNYAY, David, LEOPOLD, Philip L, MERRITT, Robert, HACKETT, Neil R, ROVELINK, Peter W, BRUDER, Joseph T, WICKHAM, Thomas J
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.03.2004
• Subjects: Adenoviridae - genetics; Adenoviridae - physiology; Adenovirus; Animals; Antibody Formation; beta-Galactosidase - genetics; beta-Galactosidase - immunology; Biological and medical sciences; Cancer Vaccines - genetics; Cancer Vaccines - immunology; Capsid Proteins - genetics; Capsid Proteins - metabolism; CD4-Positive T-Lymphocytes - immunology; CD8-Positive T-Lymphocytes - immunology; Dendritic Cells - immunology; Dendritic Cells - virology; Fundamental and applied biological sciences. Psychology; Gene Therapy; Genes, Reporter - genetics; Genetic Therapy - methods; Genetic Vectors - genetics; Immunity, Cellular; Immunization; Mice; Mice, Inbred C57BL; Microbiology; Miscellaneous; Neoplasms - genetics; Neoplasms - immunology; Neoplasms - pathology; Neoplasms - therapy; Survival Rate; Transgenes - genetics; Virology; Virus; Dendritic cell; Modification; Adenoviridae; Microbiology; Cellular immunity; Capsid; Vector; Virology

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