Flow Mediated Dilation in Systemic Sclerosis: Association with clinical findings, capillaroscopic patterns and endothelial circulating markers

• Published in: Vascular pharmacology Vol. 154; p. 107252
• Main Authors: Corrado, Addolorata, Mansueto, Natalia, Correale, Michele, Rella, Valeria, Tricarico, Lucia, Altomare, Alberto, Brunetti, Natale Daniele, Cantatore, Francesco Paolo, Rotondo, Cinzia
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.03.2024
• Subjects: Angiopoietin-2; Cardiovascular; Dilatation; Endothelial activation markers; Endothelial dysfunction; Flow mediated dilation; Humans; Microscopic Angioscopy; Nailfold video-capillaroscopy; Pulmonary Arterial Hypertension; Scleroderma, Systemic - complications; Scleroderma, Systemic - diagnosis; Scleroderma, Systemic - pathology; Skin Ulcer; Systemic sclerosis; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor A; Endothelial dysfunction; Endothelial activation markers; Systemic sclerosis; Flow mediated dilation; Nailfold video-capillaroscopy

Endothelial dysfunction represents a key feature of the pathological process underlying micro and macro-vascular damage in Systemic Sclerosis (SSc). This study aims to improve knowledge of the physiopathology of vascular damage in SSc through the assessment of the endothelial dysfunction by Flow Med...