Biomarkers for the diagnosis and risk stratification of acute kidney injury: A systematic review

• Published in: Kidney international Vol. 73; no. 9; pp. 1008 - 1016
• Main Authors: Coca, S.G., Yalavarthy, R., Concato, J., Parikh, C.R.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.05.2008; Nature Publishing; Elsevier Limited
• Subjects: Acute Kidney Injury - blood; Acute Kidney Injury - diagnosis; Acute Kidney Injury - urine; acute renal failure; Biological and medical sciences; Biomarkers - blood; Biomarkers - urine; clinical epidemiology; creatinine; diagnosis; Humans; Kidneys; Medical sciences; mortality; Nephrology. Urinary tract diseases; Nephropathies. Renovascular diseases. Renal failure; Renal failure; renal injury; Risk Assessment; Urinary system involvement in other diseases. Miscellaneous; mortality; diagnosis; creatinine; acute renal failure; clinical epidemiology; renal injury; Kidney disease; Creatinine; Nephrology; Urinary system disease; Acute kidney injury; Mortality; Biological marker; Biological indicator; Review; Kidney traumatism; Epidemiology; Urology; Acute renal failure; Risk factor; Diagnosis; Bibliographic review

The diagnosis of acute kidney injury (AKI) is usually based on changes in serum creatinine, but such measurements are a poor marker of acute deterioration in kidney function. We performed a systematic review of publications that evaluated the accuracy and reliability of serum and urinary biomarkers...