Sublethal cytochrome c release generates drug-tolerant persister cells - Kalkavan, Halime; Chen, Mark J.; Crawford, Jeremy C.; Quarato, Giovanni; Fitzgerald, Patrick; Tait, Stephen W.G.; Goding, Colin R.; Green, Douglas R. (Cell, 2022)
Keywords: Animals; Apoptosis; cancer therapy; Carrier Proteins; caspases; Caspases - metabolism; cytochrome c; Cytochromes c - metabolism; Drug Resistance, Neoplasm; ferroptosis; Humans; membrane permeability; metastasis; Mice; mitochondria; Mitochondria - metabolism; Neoplasms - drug therapy; phenotype; stress response; ferroptosis; GPX4; HRI; ATF4; Bcl-2 family; persister integrated stress response