In vivo oxidative degradation of polypropylene pelvic mesh
Abstract Commercial polypropylene pelvic mesh products were characterized in terms of their chemical compositions and molecular weight characteristics before and after implantation. These isotactic polypropylene mesh materials showed clear signs of oxidation by both Fourier-transform infrared spectr...
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Published in | Biomaterials Vol. 73; pp. 131 - 141 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
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01.12.2015
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Abstract | Abstract Commercial polypropylene pelvic mesh products were characterized in terms of their chemical compositions and molecular weight characteristics before and after implantation. These isotactic polypropylene mesh materials showed clear signs of oxidation by both Fourier-transform infrared spectroscopy and scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM/EDS). The oxidation was accompanied by a decrease in both weight-average and z-average molecular weights and narrowing of the polydispersity index relative to that of the non-implanted material. SEM revealed the formation of transverse cracking of the fibers which generally, but with some exceptions, increased with implantation time. Collectively these results, as well as the loss of flexibility and embrittlement of polypropylene upon implantation as reported by other workers, may only be explained by in vivo oxidative degradation of polypropylene. |
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AbstractList | Commercial polypropylene pelvic mesh products were characterized in terms of their chemical compositions and molecular weight characteristics before and after implantation. These isotactic polypropylene mesh materials showed clear signs of oxidation by both Fourier-transform infrared spectroscopy and scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM/EDS). The oxidation was accompanied by a decrease in both weight-average and z-average molecular weights and narrowing of the polydispersity index relative to that of the non-implanted material. SEM revealed the formation of transverse cracking of the fibers which generally, but with some exceptions, increased with implantation time. Collectively these results, as well as the loss of flexibility and embrittlement of polypropylene upon implantation as reported by other workers, may only be explained by in vivo oxidative degradation of polypropylene. Commercial polypropylene pelvic mesh products were characterized in terms of their chemical compositions and molecular weight characteristics before and after implantation. These isotactic polypropylene mesh materials showed clear signs of oxidation by both Fourier-transform infrared spectroscopy and scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM/EDS). The oxidation was accompanied by a decrease in both weight-average and z-average molecular weights and narrowing of the polydispersity index relative to that of the non-implanted material. SEM revealed the formation of transverse cracking of the fibers which generally, but with some exceptions, increased with implantation time. Collectively these results, as well as the loss of flexibility and embrittlement of polypropylene upon implantation as reported by other workers, may only be explained by in vivo oxidative degradation of polypropylene. Abstract Commercial polypropylene pelvic mesh products were characterized in terms of their chemical compositions and molecular weight characteristics before and after implantation. These isotactic polypropylene mesh materials showed clear signs of oxidation by both Fourier-transform infrared spectroscopy and scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM/EDS). The oxidation was accompanied by a decrease in both weight-average and z-average molecular weights and narrowing of the polydispersity index relative to that of the non-implanted material. SEM revealed the formation of transverse cracking of the fibers which generally, but with some exceptions, increased with implantation time. Collectively these results, as well as the loss of flexibility and embrittlement of polypropylene upon implantation as reported by other workers, may only be explained by in vivo oxidative degradation of polypropylene. |
Author | Gido, Samuel Malmgren, Thomas Imel, Adam Mays, Jimmy Dadmun, Mark |
Author_xml | – sequence: 1 fullname: Imel, Adam – sequence: 2 fullname: Malmgren, Thomas – sequence: 3 fullname: Dadmun, Mark – sequence: 4 fullname: Gido, Samuel – sequence: 5 fullname: Mays, Jimmy |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/26408998$$D View this record in MEDLINE/PubMed |
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Keywords | Degradation Oxidation Polypropylene SEM (scanning electron microscopy) Molecular weight |
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Snippet | Abstract Commercial polypropylene pelvic mesh products were characterized in terms of their chemical compositions and molecular weight characteristics before... Commercial polypropylene pelvic mesh products were characterized in terms of their chemical compositions and molecular weight characteristics before and after... |
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SubjectTerms | Advanced Basic Science Antioxidants - chemistry Biocompatible Materials Biomedical materials Degradation Dentistry Equipment Design Humans Implantation In vivo tests Materials Testing Microscopy, Electron, Scanning Molecular Weight Oxidation Oxygen - chemistry Polymers - chemistry Polypropylene Polypropylenes Polypropylenes - chemistry Prostheses and Implants Prosthesis Failure Scanning electron microscopy SEM (scanning electron microscopy) Spectrometry, X-Ray Emission Spectroscopy, Fourier Transform Infrared Stress, Mechanical Surgical implants Surgical Mesh Thermogravimetry |
Title | In vivo oxidative degradation of polypropylene pelvic mesh |
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