In vivo oxidative degradation of polypropylene pelvic mesh

Abstract Commercial polypropylene pelvic mesh products were characterized in terms of their chemical compositions and molecular weight characteristics before and after implantation. These isotactic polypropylene mesh materials showed clear signs of oxidation by both Fourier-transform infrared spectr...

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Published inBiomaterials Vol. 73; pp. 131 - 141
Main Authors Imel, Adam, Malmgren, Thomas, Dadmun, Mark, Gido, Samuel, Mays, Jimmy
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ltd 01.12.2015
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Abstract Abstract Commercial polypropylene pelvic mesh products were characterized in terms of their chemical compositions and molecular weight characteristics before and after implantation. These isotactic polypropylene mesh materials showed clear signs of oxidation by both Fourier-transform infrared spectroscopy and scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM/EDS). The oxidation was accompanied by a decrease in both weight-average and z-average molecular weights and narrowing of the polydispersity index relative to that of the non-implanted material. SEM revealed the formation of transverse cracking of the fibers which generally, but with some exceptions, increased with implantation time. Collectively these results, as well as the loss of flexibility and embrittlement of polypropylene upon implantation as reported by other workers, may only be explained by in vivo oxidative degradation of polypropylene.
AbstractList Commercial polypropylene pelvic mesh products were characterized in terms of their chemical compositions and molecular weight characteristics before and after implantation. These isotactic polypropylene mesh materials showed clear signs of oxidation by both Fourier-transform infrared spectroscopy and scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM/EDS). The oxidation was accompanied by a decrease in both weight-average and z-average molecular weights and narrowing of the polydispersity index relative to that of the non-implanted material. SEM revealed the formation of transverse cracking of the fibers which generally, but with some exceptions, increased with implantation time. Collectively these results, as well as the loss of flexibility and embrittlement of polypropylene upon implantation as reported by other workers, may only be explained by in vivo oxidative degradation of polypropylene.
Commercial polypropylene pelvic mesh products were characterized in terms of their chemical compositions and molecular weight characteristics before and after implantation. These isotactic polypropylene mesh materials showed clear signs of oxidation by both Fourier-transform infrared spectroscopy and scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM/EDS). The oxidation was accompanied by a decrease in both weight-average and z-average molecular weights and narrowing of the polydispersity index relative to that of the non-implanted material. SEM revealed the formation of transverse cracking of the fibers which generally, but with some exceptions, increased with implantation time. Collectively these results, as well as the loss of flexibility and embrittlement of polypropylene upon implantation as reported by other workers, may only be explained by in vivo oxidative degradation of polypropylene.
Abstract Commercial polypropylene pelvic mesh products were characterized in terms of their chemical compositions and molecular weight characteristics before and after implantation. These isotactic polypropylene mesh materials showed clear signs of oxidation by both Fourier-transform infrared spectroscopy and scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM/EDS). The oxidation was accompanied by a decrease in both weight-average and z-average molecular weights and narrowing of the polydispersity index relative to that of the non-implanted material. SEM revealed the formation of transverse cracking of the fibers which generally, but with some exceptions, increased with implantation time. Collectively these results, as well as the loss of flexibility and embrittlement of polypropylene upon implantation as reported by other workers, may only be explained by in vivo oxidative degradation of polypropylene.
Author Gido, Samuel
Malmgren, Thomas
Imel, Adam
Mays, Jimmy
Dadmun, Mark
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Keywords Degradation
Oxidation
Polypropylene
SEM (scanning electron microscopy)
Molecular weight
Language English
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Snippet Abstract Commercial polypropylene pelvic mesh products were characterized in terms of their chemical compositions and molecular weight characteristics before...
Commercial polypropylene pelvic mesh products were characterized in terms of their chemical compositions and molecular weight characteristics before and after...
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SubjectTerms Advanced Basic Science
Antioxidants - chemistry
Biocompatible Materials
Biomedical materials
Degradation
Dentistry
Equipment Design
Humans
Implantation
In vivo tests
Materials Testing
Microscopy, Electron, Scanning
Molecular Weight
Oxidation
Oxygen - chemistry
Polymers - chemistry
Polypropylene
Polypropylenes
Polypropylenes - chemistry
Prostheses and Implants
Prosthesis Failure
Scanning electron microscopy
SEM (scanning electron microscopy)
Spectrometry, X-Ray Emission
Spectroscopy, Fourier Transform Infrared
Stress, Mechanical
Surgical implants
Surgical Mesh
Thermogravimetry
Title In vivo oxidative degradation of polypropylene pelvic mesh
URI https://www.clinicalkey.es/playcontent/1-s2.0-S0142961215007607
https://dx.doi.org/10.1016/j.biomaterials.2015.09.015
https://www.ncbi.nlm.nih.gov/pubmed/26408998
https://search.proquest.com/docview/1722188103
https://search.proquest.com/docview/1727698049
https://search.proquest.com/docview/1762109446
Volume 73
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