Detecting neurobehavioral changes in amyotrophic lateral sclerosis

• Published in: Amyotrophic lateral sclerosis Vol. 8; no. 1; pp. 56 - 61
• Main Authors: Grossman, Alison B., Woolley-Levine, Susan, Bradley, Walter G., Miller, Robert G.
• Format: Journal Article
• Language: English
• Published: England Informa UK Ltd 2007; Taylor & Francis
• Subjects: Aged; ALS; Amyotrophic Lateral Sclerosis - complications; Amyotrophic Lateral Sclerosis - epidemiology; Amyotrophic Lateral Sclerosis - psychology; Analysis of Variance; behavioral assessment; Behavioral Symptoms - epidemiology; Behavioral Symptoms - etiology; caregiver reports; Cognition Disorders - epidemiology; Cognition Disorders - etiology; Female; Frontal Systems Behavior Scale; Humans; Incidence; Male; Middle Aged; Neuropsychological Tests

Cognitive impairment in patients with amyotrophic lateral sclerosis (ALS) is well documented, but behavioral abnormalities are not well defined. The Frontal Systems Behavior Scale (FrSBe) was used to assess changes in apathy, disinhibition, and executive dysfunction in 45 patients with ALS. Results...