Detecting neurobehavioral changes in amyotrophic lateral sclerosis
Cognitive impairment in patients with amyotrophic lateral sclerosis (ALS) is well documented, but behavioral abnormalities are not well defined. The Frontal Systems Behavior Scale (FrSBe) was used to assess changes in apathy, disinhibition, and executive dysfunction in 45 patients with ALS. Results...
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| Published in | Amyotrophic lateral sclerosis Vol. 8; no. 1; pp. 56 - 61 |
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| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
Informa UK Ltd
2007
Taylor & Francis |
| Subjects | |
| Online Access | Get full text |
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| Abstract | Cognitive impairment in patients with amyotrophic lateral sclerosis (ALS) is well documented, but behavioral abnormalities are not well defined. The Frontal Systems Behavior Scale (FrSBe) was used to assess changes in apathy, disinhibition, and executive dysfunction in 45 patients with ALS. Results suggest a high incidence of behavioral change, most notably in apathy associated with the onset of the disease and independent of mood. Apathy and verbal fluency were correlated, lending further support to the hypothesis that an underlying continuum exists between ALS and frontotemporal dementia (FTD), which is characterized predominantly by behavioral disturbance. The FrsBe is useful for detecting behavioral change and abnormalities in patients with ALS. |
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| AbstractList | Cognitive impairment in patients with amyotrophic lateral sclerosis (ALS) is well documented, but behavioral abnormalities are not well defined. The Frontal Systems Behavior Scale (FrSBe) was used to assess changes in apathy, disinhibition, and executive dysfunction in 45 patients with ALS. Results suggest a high incidence of behavioral change, most notably in apathy associated with the onset of the disease and independent of mood. Apathy and verbal fluency were correlated, lending further support to the hypothesis that an underlying continuum exists between ALS and frontotemporal dementia (FTD), which is characterized predominantly by behavioral disturbance. The FrsBe is useful for detecting behavioral change and abnormalities in patients with ALS. |
| Author | Woolley-Levine, Susan Grossman, Alison B. Bradley, Walter G. Miller, Robert G. |
| Author_xml | – sequence: 1 givenname: Alison B. surname: Grossman fullname: Grossman, Alison B. email: agrossman@med.miami.edu organization: 1Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida – sequence: 2 givenname: Susan surname: Woolley-Levine fullname: Woolley-Levine, Susan email: agrossman@med.miami.edu organization: 1Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida – sequence: 3 givenname: Walter G. surname: Bradley fullname: Bradley, Walter G. email: agrossman@med.miami.edu organization: 1Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida – sequence: 4 givenname: Robert G. surname: Miller fullname: Miller, Robert G. email: agrossman@med.miami.edu organization: 1Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/17364437$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1080/146608200300079536 10.1017/S0317167100021053 10.1016/S0926-6410(02)00110-6 10.1136/jnnp.62.5.464 10.1159/000077167 10.1016/S0028-3932(99)00146-3 10.1136/jnnp.53.1.23 10.1212/01.WNL.0000055861.95202.8D 10.1212/WNL.53.8.1665 10.1016/S0022-510X(00)00425-1 10.1093/brain/awh170 10.1097/00006842-197003000-00002 10.1212/01.wnl.0000172911.39167.b6 10.1007/s00401-004-0900-9 10.1093/neucas/7.2.123 10.1001/archneur.1996.00550020045014 |
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| SubjectTerms | Aged ALS Amyotrophic Lateral Sclerosis - complications Amyotrophic Lateral Sclerosis - epidemiology Amyotrophic Lateral Sclerosis - psychology Analysis of Variance behavioral assessment Behavioral Symptoms - epidemiology Behavioral Symptoms - etiology caregiver reports Cognition Disorders - epidemiology Cognition Disorders - etiology Female Frontal Systems Behavior Scale Humans Incidence Male Middle Aged Neuropsychological Tests |
| Title | Detecting neurobehavioral changes in amyotrophic lateral sclerosis |
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