Bifunctional Magnetite–Gold Nanoparticles for Magneto-Mechanical Actuation and Cancer Cell Destruction

• Published in: Magnetochemistry Vol. 8; no. 12; p. 185
• Main Authors: Garanina, Anastasiia S., Efremova, Maria V., Machulkin, Alexey E., Lyubin, Evgeny V., Vorobyeva, Natalia S., Zhironkina, Oxana A., Strelkova, Olga S., Kireev, Igor I., Alieva, Irina B., Uzbekov, Rustem E., Agafonov, Viatcheslav N., Shchetinin, Igor V., Fedyanin, Andrey A., Erofeev, Alexander S., Gorelkin, Peter V., Korchev, Yuri E., Savchenko, Alexander G., Abakumov, Maxim A.
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.12.2022; MDPI
• Subjects: Acids; Actuation; Analysis; Apoptosis; Aqueous solutions; Atomic Physics; Biocompatibility; biomedical application; Biomedical materials; Cancer; cancer cell destruction; Chains; Chemical Sciences; Chemical synthesis; Cytoplasm; Destruction; Diffraction; Endosomes; Gene expression; Gold; Gold compounds; High temperature; Hyperthermia; Iron oxides; Life Sciences; low-frequency magnetic field; Magnetic fields; Magnetic properties; Magnetic resonance imaging; Magnetic saturation; Magnetite; magnetite–gold dumbbell nanoparticles; Material chemistry; Mechanical properties; Methods; Nanoparticles; Physics; prostate cancer cells; Rotation; SICM; Software; Structure; Transmission electron microscopes; Transmission electron microscopy; X-rays; United Kingdom; Russia; United States > US; Prostate cancer cells; magnetite–gold dumbbell nanoparticles; low-frequency magnetic field; Biomedical application; Cancer cell destruction

Magnetite–gold dumbbell nanoparticles are essential for biomedical applications due to the presence of two surfaces with different chemical natures and the potential combination of magnetic and plasmonic properties. Here, the remote actuation of Fe3O4-Au hybrid particles in a rotating (1 Hz, 7 mT),...