Human autoimmune diseases: a comprehensive update

• Published in: Journal of internal medicine Vol. 278; no. 4; pp. 369 - 395
• Main Authors: Wang, Lifeng, Wang, Fu‐Sheng, Gershwin, M. Eric
• Format: Journal Article
• Language: English
• Published: England 01.10.2015
• Subjects: autoantibodies; Autoimmune Diseases - epidemiology; Autoimmune Diseases - etiology; Autoimmune Diseases - genetics; Autoimmune Diseases - therapy; Environmental Exposure; Female; Genetic Predisposition to Disease; genetics and autoimmunity; Humans; Immune Tolerance; Immunopathology; Male; Models, Biological; Twin Studies as Topic; Immunopathology; autoantibodies; genetics and autoimmunity; Immune tolerance

There have been significant advances in our understanding of human autoimmunity that have led to improvements in classification and diagnosis and, most importantly, research advances in new therapies. The importance of autoimmunity and the mechanisms that lead to clinical disease were first recogniz...