GDF‐15 is associated with atherosclerosis in adults with transfusion‐dependent beta‐thalassemia

• Published in: EJHaem Vol. 3; no. 2; pp. 353 - 361
• Main Authors: Efat, Alaa, Wahb, Rana, Shoeib, Sabry Abd Allah, Dawod, Ashraf Abd ElRaof, Abd ElHafez, Mohamad Ahmed, Abd ElMohsen, Essam Ali, Elkholy, Aly
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.05.2022; John Wiley and Sons Inc; Wiley
• Subjects: Arteriosclerosis; Atherosclerosis; Blood diseases; Blood tests; Blood transfusions; Cardiovascular disease; Carotid arteries; CIMT; Doppler effect; Ethics; Family medical history; GDF‐15; Genetic disorders; Heart failure; Hematology; Hemoglobin; Hypertension; Insulin resistance; Iron; Ischemia; Patients; Sickle Cell, Thrombosis, and Benign Haematology; Statistical analysis; Thalassemia; transfusion‐dependent beta‐thalassemic adults; Ultrasonic imaging; GDF‐15; transfusion‐dependent beta‐thalassemic adults; CIMT

Objectives: To study serum growth differentiation factor‐15 (GDF‐15) serum level in β‐thalassemia patients and its relation to carotid intima‐media thickness. Background: Thalassemia is a common genetic disease resulting in decreased beta‐chains, leading to manifested anemia. It may be subsequently...