Metabolic Predictors of Incident Coronary Heart Disease in Women

• Published in: Circulation (New York, N.Y.) Vol. 137; no. 8; pp. 841 - 853
• Main Authors: Paynter, Nina P, Balasubramanian, Raji, Giulianini, Franco, Wang, Dong D, Tinker, Lesley F, Gopal, Shuba, Deik, Amy A, Bullock, Kevin, Pierce, Kerry A, Scott, Justin, Martínez-González, Miguel A, Estruch, Ramon, Manson, JoAnn E, Cook, Nancy R, Albert, Christine M, Clish, Clary B, Rexrode, Kathryn M
• Format: Journal Article
• Language: English
• Published: United States by the American College of Cardiology Foundation and the American Heart Association, Inc 20.02.2018
• Subjects: Aged; Chromatography, Liquid; Coronary Disease - blood; Coronary Disease - epidemiology; Female; Humans; Incidence; Metabolomics; Middle Aged; Phosphatidylcholines - blood; Predictive Value of Tests; Risk Factors; Tandem Mass Spectrometry; coronary disease; lipids; risk; metabolomics; women

BACKGROUND:Although metabolomic profiling offers promise for the prediction of coronary heart disease (CHD), and metabolic risk factors are more strongly associated with CHD in women than men, limited data are available for women. METHODS:We applied a liquid chromatography–tandem mass spectrometry m...