Predictors and clinical complications associated with antiphospholipid antibodies in sickle cell disease

• Published in: EJHaem Vol. 4; no. 1; pp. 211 - 215
• Main Authors: Rivera, Claudia Rodriguez, Srisuwananukorn, Andrew, Bajwa, Rizma Jalees, Gordeuk, Victor R., Rauch, Joyce, Levine, Jerrold S., Saraf, Santosh L.
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.02.2023; John Wiley and Sons Inc; Wiley
• Subjects: Age; Anemia; Anticoagulants; Antiphospholipid antibodies; antiphospholipid antibody; antiphospholipid syndrome; Autoantibodies; Blood; Blood diseases; Blood levels; Blood platelets; Genotype & phenotype; Glycoproteins; Hemoglobin; Kruskal-Wallis test; Laboratories; Lupus; multiorgan failure; Pre-eclampsia; Pregnancy complications; Regression analysis; Risk factors; Short Report; Short Reports; Sickle cell disease; systemic lupus erythematosus; Trends; Vascular diseases; Womens health; United States > US; antiphospholipid antibody; antiphospholipid syndrome; systemic lupus erythematosus; multiorgan failure; sickle cell disease

Although a higher prevalence of antiphospholipid autoantibodies (aPL) has been observed in some cohorts of sickle cell disease (SCD) patients, the clinical risk factors for the development of aPL and its associated complications remain unclear. In a retrospective study of 63 SCD patients, a lower he...