Dietary Plant Sterols Supplementation Increases In Vivo Nitrite and Nitrate Production in Healthy Adults: A Randomized, Controlled Study

• Published in: Journal of food science Vol. 82; no. 7; pp. 1750 - 1756
• Main Authors: Ho, Xing Lin, Loke, Wai Mun
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.07.2017; John Wiley and Sons Inc
• Subjects: Adult; Adults; Arginine; Arginine - analogs & derivatives; Arginine - metabolism; beta-sitosterol; Beverages; Blood; Blood circulation; Blood plasma; blood serum; Body mass; Body mass index; campesterol; Cholesterol - analogs & derivatives; Cross-Over Studies; Dietary supplements; Dietary Supplements - analysis; Enriched foods; enzyme immunoassays; Esters; Female; females; Food matrix; Food plants; Gas chromatography; Gas Chromatography-Mass Spectrometry; Health, Nutrition, & Food; Health, Nutrition, and Food; Humans; Immunoassays; In vivo methods and tests; Low density lipoprotein; L‐arginine; Male; Mass spectrometry; Mass spectroscopy; Middle Aged; nitrate; Nitrates; Nitrates - blood; Nitrates - metabolism; Nitrates - urine; Nitric oxide; nitrite; Nitrites; Nitrites - blood; Nitrites - metabolism; Nitrites - urine; Phytosterols - metabolism; placebos; plant sterols; Plant-based beverages; Plasmas (physics); Randomization; Soybean milk; soymilk; Stable isotopes; Sterols; stigmasterol; Studies; Urine; Young Adult; nitric oxide; nitrite; nitrate; plant sterols; L-arginine

A randomized, double‐blinded, placebo‐controlled and crossover study was conducted to simultaneously measure the effects, 3 h after consumption and after 4‐wk daily exposure to plant sterols‐enriched food product, on in vivo nitrite and nitrate production in healthy adults. Eighteen healthy particip...